During failure of core protein quality control in the nematode C. elegans, a specialized anti-aggregation mechanism relying on pathogen response factors and lysosomal mediated degradation is triggered
Promoting tissue-specific resilience to age-dependent protein aggregation and its proteotoxicity
Published 2023-09-14 · Original archive entry · Explore research explainers
During failure of core protein quality control in the nematode C. elegans, a specialized anti-aggregation mechanism relying on pathogen response factors and lysosomal mediated degradation is triggered, promoting tissue-specific resilience to age-dependent protein aggregation and its proteotoxicity.
#####
In your coverage, please use this URL to provide access to the freely available paper in PLOS Biology: http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002284
Article Title: A safety mechanism enables tissue-specific resistance to protein aggregation during aging in C. elegans
Author Countries: Germany, United Kingdom
Funding: see manuscript
END
Attachments
