(Press-News.org) About The Study: In this randomized clinical trial, early treatment with metformin was not superior to placebo for the composite primary outcome of insulin initiation or a fasting glucose level of 5.1 mmol/L or greater at gestation weeks 32 or 38. Prespecified secondary outcome data support further investigation of metformin in larger clinical trials.
Authors: Fidelma Dunne, Ph.D., of the University of Galway in Galway, Ireland, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2023.19869)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
Media advisory: This study is being released to coincide with presentation at the European Association for the Study of Diabetes Annual Meeting 2023.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2023.19869?guestAccessKey=8568ea62-6457-41dc-8a4d-c197f621be42&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=100323
END
Early metformin in gestational diabetes
JAMA
2023-10-03
ELSE PRESS RELEASES FROM THIS DATE:
Tirzepatide vs insulin lispro added to basal insulin in type 2 diabetes
2023-10-03
About The Study: In people with inadequately controlled type 2 diabetes treated with basal insulin in this randomized clinical trial with 1,428 participants, weekly tirzepatide compared with prandial insulin as an additional treatment with insulin glargine demonstrated reductions in HbA1c and body weight with less hypoglycemia.
Authors: Julio Rosenstock, M.D., of Velocity Clinical Research at Medical City in Dallas, is the corresponding author.
To access the embargoed study: Visit our For The Media ...
New biobanking partnership safeguards the genetic diversity of America’s endangered species
2023-10-03
San Francisco, CA - The nonprofit Revive & Restore announces a groundbreaking new initiative to biobank U.S. endangered species, in partnership with the U.S. Fish & Wildlife Service. This multi-institution collaboration is the first systematic biobanking pipeline for U.S. threatened and endangered species. The initiative will protect genetic diversity for current and future recovery efforts.
"This is about creating a legacy of America’s natural history before it is lost and provides an important resource to enhance species recovery efforts now and in the future,” said Ryan Phelan, Executive Director of Revive & ...
Eating disorders increased during pandemic in female adolescents and adults
2023-10-03
Emergency department (ED) visits and hospital admissions for eating disorders increased during the COVID-19 pandemic in adolescents aged 10–17 years, as did ED visits among young adults and older adults, according to new research published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.221318.
Using ICES data, researchers compared observed and expected rates of ED visits and hospitalizations for eating disorders before (Jan. 1, 2017, to Feb. 29, 2020) and during the pandemic (Mar. 1, 2020, to Aug. 31, 2022) in adolescents (10–17 years), young adults (18–26 years), adults (27–40 years) ...
Improved mangrove conservation could yield cash, carbon, coastal benefits
2023-10-03
A shift in the way we think about the benefits mangroves provide to coastal regions could yield significant economic and biodiversity gains and protect millions from flooding, research has revealed.
The University of Queensland-led study shows current conservation efforts typically target biodiversity protection whilst minimising conflict with economic interests, while failing to consider the huge benefits provided by ecosystems.
Alvise Dabalà, now at the University of the Azores and whose Masters project at UQ formed the basis of this study, said human activities, such as deforestation and coastal development have led to extensive ...
Brain biometrics help identify sports concussions
2023-10-03
Novel brain biometrics could help inform whether an athlete is ready to return to play following a concussion, according to new research from the University of South Australia.
Conducted in partnership with the University of California San Francisco (UCFC), researchers found that changes in micromovements of the brain – termed ‘headpulses’ – could detect the lasting impacts of a concussion.
Using a custom-designed headset* to evaluate headpulse biometrics among 101 amateur male and female Australian ...
Study uncovers reasons Americans did not get booster vaccines
2023-10-03
The paper, “Understanding low bivalent COVID-19 booster uptake among US adults,” was published in the journal Vaccine.
“Our results indicate that we have a lot more work to do in terms of educating the public and health care providers about the importance of staying up to date on COVID-19 boosters,” said first author Elizabeth Jacobs, PhD, professor of epidemiology at the Zuckerman College of Public Health, who led the research with associate professor of epidemiology Kristen Pogreba-Brown, PhD, MPH.
Nearly 40% of survey participants reported they did not get a booster shot because ...
Texas engineers land semiconductor grants through CHIPS Act-backed NSF program
2023-10-03
A pair of Cockrell School research teams are part of a massive semiconductor grant program from the National Science Foundation that includes funds from industry leaders and the federal CHIPS Act.
The projects are part of the NSF Future of Semiconductors (FuSe) program through a public-private partnership between NSF and four major tech companies: Ericsson, IBM, Intel and Samsung. FuSe aims to enable rapid progress in new semiconductor technologies and manufacturing as well as workforce development.
Altogether, the program will support 24 research and ...
Gut bacteria found in wild wolves may be key to improving domestic dogs’ health
2023-10-03
BEND, Ore. – Gut microbes found in wild wolves may be the key to alleviating a debilitating gastrointestinal condition common to domestic dogs, according to a study led by researchers at Oregon State University – Cascades.
In a paper published in Applied Microbiology, the authors report a novel strain of Paenibacillus bacteria with characteristics of a probiotic – an organism that conveys a health benefit to the host.
In this case, the benefit would be to head off canine inflammatory ...
Host genetics helps explain childhood cancer survivors’ mortality risk from second cancers
2023-10-03
(MEMPHIS, Tenn. – October 02, 2023) The population of childhood cancer survivors in the U.S. is increasing, with an overall childhood cancer survival rate greater than 85% five years after diagnosis. However, survivors can still be at increased risk of various health conditions, including second cancers. Using data from the Childhood Cancer Survivor Study (CCSS) and the St. Jude Lifetime Cohort Study (St. Jude Life), scientists at St. Jude Children’s Research Hospital have identified a genetic ...
How floods kill, long after the water has gone – global decade-long study
2023-10-03
With New York declared a state of emergency following flash flooding, there is increasing concern such events will become more common globally.
Now a study led by Monash University scientists in Australia has found that people impacted by a flooding event are at significantly increased risk of dying – including heart and lung problems – in a crucial window between three and six weeks after the event, even after the flooding has dissipated.
The study, published today in the BMJ, found that the risk of dying increased and persisted for up to 60 days (50 days for cardiovascular mortality) after a flooded day - increasing by for 2.1% for all-cause deaths, 2.6% for cardiovascular ...
LAST 30 PRESS RELEASES:
New, embodied AI reveals how robots and toddlers learn to understand
Game, set, match: Exploring the experiences of women coaches in tennis
Significant rise in mental health admissions for young people in last decade
Prehab shows promise in improving health, reducing complications after surgery
Exercise and improved diet before surgery linked to fewer complications and enhanced recovery
SGLT-2 drug plus moderate calorie restriction achieves higher diabetes remission
Could the Summerville ghost lantern be an earthquake light?
Will the U.S. have enough pain specialists?
Stronger stress response in monkeys helps them survive
Using infrared heat transfer to modify chemical reactions
Being a ladies' man comes at a price for alpha male baboons
Study shows anti-clotting drug reduced bleeding events in patients with atrial fibrillation
UMaine-led team develops more holistic way to monitor lobster industry
Antiviral protein causes genetic changes implicated in Huntington’s disease progression
SwRI-led PUNCH spacecraft make final pit stop before launch
Claims for the world’s deepest earthquake challenged by new analysis
MSU study finds children of color experience more variability in sleep times
Pregnancy may increase risk of mental illness in people with MS
Multiple sclerosis linked to higher risk of mental illness during and after pregnancy
Beyond ChatGPT: WVU researchers to study use and ethics of artificial intelligence across disciplines
Ultrasensitive test detects, serially monitors intact virus levels in patients with COVID-19
mRNA-activated blood clots could cushion the blow of osteoarthritis
Three rockets will ignite Poker Flat’s 2025 launch season
Jared M. Kutzin, DNP, MS, MPH, RN, named President of the Society for Simulation in Healthcare
PET probe images inflammation with high sensitivity and selectivity
Epilepsy patient samples offer unprecedented insights on brain ‘brakes’ linked to disorders
Your stroke risk might be higher if your parents divorced during your childhood
Life satisfaction measurement tool provides robust information across nations, genders, ages, languages
Adult children of divorced parents at higher risk of stroke
Anti-climate action groups tend to arise in countries with stronger climate change efforts
[Press-News.org] Early metformin in gestational diabetesJAMA