Adolescent body mass index and early chronic kidney disease in young adulthood

JAMA Pediatrics

2023-12-11

(Press-News.org) About The Study: High body mass index (BMI) in late adolescence was associated with early chronic kidney disease in young adulthood in this study that included 593,000 adolescents. The risk was also present in seemingly healthy individuals with high-normal BMI and before 30 years of age, and a greater risk was seen among those with severe obesity. These findings underscore the importance of mitigating adolescent obesity rates and managing risk factors for kidney disease in adolescents with high BMI.

Authors: Gilad Twig, M.D., Ph.D., of the Israel Defense Forces, Medical Corps, Tel Hashomer, Ramat Gan, Israel, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamapediatrics.2023.5420)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2023.5420?guestAccessKey=e46a96db-05e9-4331-b54a-612049629585&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=121123

END

ELSE PRESS RELEASES FROM THIS DATE:

Prenatal exposure to GLP-1 receptor agonists and other second-line antidiabetics may not pose greater risk to infants than insulin

2023-12-11

Embargoed for release: Monday, December 11, 11:00 AM ET Key points: In a study of 3.5 million pregnancies across four countries between 2009 and 2021, researchers observed no elevated risk of major congenital malformations, including major cardiac malformations, among infants born to pregnant women with pre-gestational type 2 diabetes who took second-line non-insulin antidiabetic medications compared with those who took insulin. The researchers observed an increase in use of second-line non-insulin antidiabetic ...

Potential new treatment for pulmonary neuroendocrine tumors

2023-12-11

The Organoid Group (Hubrecht Institute) and the Rare Cancers Genomics Team (IARC/WHO) found a way to grow samples of different types of neuroendocrine tumors (NETs) in the lab. While generating their new model, the researchers discovered that some pulmonary NETs need the protein EGF to be able to grow. These types of tumors may therefore be treatable using inhibitors of the EGF receptor. The results were published in Cancer Cell on 11 December 2023. Neuroendocrine tumors Neuroendocrine tumors (NETs) are relatively ...

AI chatbot shows potential as diagnostic partner, researchers find

2023-12-11

BOSTON – Physician-investigators at Beth Israel Deaconess Medical Center (BIDMC) compared a chatbot’s probabilistic reasoning to that of human clinicians. The findings, published in JAMA Network Open, suggest that artificial intelligence could serve as useful clinical decision support tools for physicians. “Humans struggle with probabilistic reasoning, the practice of making decisions based on calculating odds,” said the study’s corresponding author Adam Rodman, MD, an internal medicine physician and investigator in ...

Health impacts of abuse more extensive than previously thought, research says

2023-12-11

People who have been subject to abuse are more likely to experience physical and mental health effects than previously thought, according to a new study. In a global review and meta-analysis of evidence published in Nature Medicine today, researchers have found that there are elevated risks between intimate partner violence or childhood sexual abuse, and some health conditions including major depressive disorder, maternal miscarriage for partners, and alcohol misuse and self-harm among children. Globally, one in three ever-partnered women have experienced ...

Made-to-order diagnostic tests may be on the horizon

2023-12-11

McGill University researchers have made a breakthrough in diagnostic technology, inventing a ‘lab on a chip’ that can be 3D-printed in just 30 minutes. The chip has the potential to make on-the-spot testing widely accessible. As part of a recent study, the results of which were published in the journal Advanced Materials, the McGill team developed capillaric chips that act as miniature laboratories. Unlike other computer microprocessors, these chips are single-use and require no external power source—a simple paper strip suffices. They function through capillary action – ...

Have researchers found the missing link that explains the mysterious phenomenon known as fairy circles?

2023-12-11

BEER-SHEVA, Israel, December 11, 2023 – Fairy circles, a nearly hexagonal pattern of bare-soil circular gaps in grasslands, initially observed in Namibia and later in other parts of the world, have fascinated and baffled scientists for years. Theories for their appearance range from spatial self-organization induced by scale-dependent water-vegetation feedback to pre-existing patterns of termite nests. Prof. Ehud Meron of Ben-Gurion University of the Negev has been studying the Namibian fairy circles as a case study for understanding how ecosystems respond to water stress. He believes that all theories ...

Study reveals a protein called snail may play a role in healing brain injury

2023-12-11

WASHINGTON (Dec. 11, 2023)--A new study published in Proceedings of the National Academy of Sciences Nexus provides a better understanding of how the brain responds to injuries. Researchers at the George Washington University discovered that a protein called Snail plays a key role in coordinating the response of brain cells after an injury. The study shows that after an injury to the central nervous system (CNS) a group of localized cells start to produce Snail, a transcription factor or protein that has been implicated in the repair process.The GW researchers show that changing how much Snail is produced can significantly affect whether the injury starts ...

Continued treatment with tirzepatide for maintenance of weight reduction in adults with obesity

2023-12-11

About The Study: In participants with obesity or overweight, withdrawing tirzepatide led to substantial regain of lost weight, whereas continued treatment maintained and augmented initial weight reduction in this randomized clinical trial that included 670 adults. Authors: Louis J. Aronne, M.D., of Weill Cornell Medicine in New York, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2023.24945) Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict ...

Novel liquid biopsy of lymph fluid could guide precision treatment for head and neck cancer

2023-12-11

Lymphatic fluid from surgical drains, which is usually tossed in the trash, is a treasure in the hands of University of Pittsburgh and Washington University School of Medicine in St. Louis researchers who found that this liquid could inform more precise treatments for patients with head and neck cancer caused by human papillomavirus (HPV). The new study, published in Clinical Cancer Research, a journal of the American Association for Cancer Research, shows for the first time that HPV DNA in lymphatic fluid collected ...

LOINC® and Health Data Standards receives $4.4 million grant to expand efforts to address health inequities in EHRs

2023-12-11

INDIANAPOLIS -- LOINC® and Health Data Standards at Regenstrief Institute has received a $4.4 million grant from the Regenstrief Foundation to support expansion of work on a global initiative to categorize and standardize social determinants of health (SDOH) information into electronic health records (EHRs), an ambitious project to integrate social needs data into clinical care to more effectively address health inequities. The unequal distribution of income, food, safety and access to healthcare are recognized as root causes of health disparities. But, currently, data on these factors are rarely well documented within a patient’s ...

TF-rs1049296 C>T variant modifies the association between hepatic iron stores and liver fibrosis in metabolic dysfunction-associated steatotic liver disease

ASH publishes clinical practice guidelines on diagnosis of light chain amyloidosis

SLAS receives grant from Alfred P. Sloan Foundation to develop lab automation educational guidelines

Serum interleukin-8 for differentiating invasive pulmonary aspergillosis from bacterial pneumonia in patients with HBV-associated acute-on-chronic liver failure

Adolescent body mass index and early chronic kidney disease in young adulthood

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: