(Press-News.org) Environmental epidemiologists at Columbia University Mailman School of Public Health, in collaboration with an interdisciplinary team of researchers at Oregon State University, Pacific Northwest National Labs, and Mt. Sinai School of Medicine, report on the findings of a new study of air pollution exposures collected using personal wristband monitors worn by pregnant individuals in New York City matched with data from a questionnaire. Factors predictive of exposures to air pollution include income, time spent outdoors, maternal age, country of birth, transportation type, and season.
The researchers examined an unprecedented number of 61 air pollution compounds known as polycyclic aromatic hydrocarbons (PAHs) and compared them to 75 questionnaire variables, making the study the most comprehensive analysis of its kind. PAHs are created by combustion and can be found in sources like automotive exhaust and tobacco smoke; exposure to these compounds has been linked to various adverse health effects, including those related to fetal growth and neurodevelopment. The study’s findings appear online in the Journal of Exposure Science And Environmental Epidemiology(link is external and opens in a new window).
Participants, 177 of whom were included in the final analysis, wore silicone wristbands for 48 hours during the third trimester of pregnancy to measure exposure to PAHs. They completed a questionnaire during the third trimester of their pregnancy, answering questions related to demographic and employment information, as well as their potential exposure sources, such as cooking, smoking, and transportation.
Julie Herbstman, PhD, director of the Columbia Center for Children’s Environmental Health and senior author of the study, commented, “This study represents a significant advancement in our understanding of personal PAH exposure. By uncovering the variables that play a crucial role in exposure levels, we are better equipped to develop interventions aimed at reducing health risks.”
Previous studies have been restricted to a limited number of compounds or specific exposure scenarios (e.g. toll station workers or cooks). Compared to these studies, the new study demonstrated substantially improved predictability due to the use of a larger dataset, as well as the use of a regression tree analysis, which accounted for each PAH compound as well as combined exposure to all PAHs. This approach helps researchers to identify those variables that are most important and/or predictive of exposure to a compound in the context of all other variables.
Sarah McLarnan, MPH, a PhD candidate at Columbia Mailman and the study’s first author, adds, “This study underscored the utility of silicone wristbands in evaluating PAH exposures and associated health outcomes. By combining questionnaire data with a 48-hour wristband deployment, we were able to refine measurements of exposure sources in terms of time and space, enabling more accurate source characterization.”
The study uncovered complex interactions between demographics and behaviors that shape exposure to individual compounds in different ways. Insights it gleaned require further study to understand the pathways by which various factors are linked to PAH exposures. As one example, the researchers are interested to know how maternal age and income are associated with behaviors or residential characteristics that are protective from some exposure sources but were shown to have opposite effect for some of the individual compounds.
The authors note that the wristbands are unable to detect all exposures to PAHs, particularly exposures via food. And because the wristbands were worn only for 48 hours, the exposures might not fully reflect an individual’s average exposure over the course of pregnancy.
We all can reduce our exposure to PAHs by avoiding tobacco smoke and ensuring we have good indoor ventilation, especially when cooking; reduce our intake of smoked, grilled, and charbroiled foods; limit exposure to diesel fumes and wood smoke; use cedar shavings or blocks in place of mothballs for pest control; and wear gloves to avoid skin contact with soot or creosote-treated lumber, and wear a mask if cutting treated lumber.
Previous research by the Columbia Center for Children’s Environmental Health has linked prenatal exposure to PAHs with numerous adverse outcomes in the child, including asthma, obesity, and developmental delays.
Additional co-authors include Lehyla Calero, Darrell Holmes, Elizabeth A. Gibson, and Haleigh M. Cavalier from Columbia University Mailman School of Public Health; Lisa M. Bramer and Katrina M. Waters from Pacific Northwest National Laboratory; Holly M. Dixon and Kim A. Anderson from Oregon State University; Diana Rohlman and Laurel Kincl from Oregon State University; and Rachel L. Miller from Icahn School of Medicine at Mount Sinai.
This research was supported by National Institute of Health grants UH3OD023290, 1R21ES024718, 4R33ES024718, P30ES030287, P42ES016465, T32 ES007322; TRANSFORM TL-1 Fellowship 5TL1TR001875-07. Anderson and Rohlman disclose a financial interest in MyExposome, Inc., which is marketing products related to the research being reported. The authors have no other relevant financial or non-financial interests to disclose.
END
Wristband monitors provide detailed account of air pollution exposure
2024-01-10
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