PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Risks associated with secondhand smoke in cars carrying children

2011-01-11
(Press-News.org) While the evidence is incomplete there is enough available to support legislation against letting people smoke in cars with children, states an article in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj100903.pdf.

This analysis was conducted to settle the matter of risk to children when in a car with second-hand smoke. The authors also wanted to show that although smoking in cars is not 23 times more toxic in a car than in a home it can still be very harmful to children.

"We hope to show that, though the relevant data are rich and complex, a simple conclusion is possible," writes Dr. Ray Pawson, School of Sociology and Social Policy, University of Leeds, United Kingdom with coauthors. "The evidence does not show an absolute risk threshold because a range of environmental, biological and social factors contribute to the risk equation. The evidence does, however, show conditional truths, and the careful enunciation of each contributory condition is the task of public health science."

While trying to determine the risks involved, the authors first looked at the mixture of chemicals that make up second-hand smoke and its concentration in cars under different conditions such as volume, speed and ventilation. Second, they looked at how long a person would be in the car. Third, they observed how long a person would be exposed to the second-hand smoke. Fourth, the extent of difference between how second-hand smoke affects children compared to adults was added to the risk equation and finally, the authors looked at the health impact, which is hard to determine because of all the different chemicals and toxins a person is exposed to in their lifetime.

"Policy based on science and evidence has to exist amid uncertainty and this is managed by acknowledging the contingencies," write the authors. "Thus, i) because of the confirmed cabin space, and ii) under the worst ventilation conditions, and iii) in terms of peak contamination, the evidence permits us to say that smoking in cars generates fine particulate concentrations that are, iv) very rarely experienced in the realm of air-quality studies, and that will thus constitute a significant health risk because, v) exposure to smoking in cars is still commonplace , and vi) children are particularly susceptible and vii) are open to further contamination if their parents are smokers."

The authors conclude that there is enough evidence to make a valid decision to legislate against smoking in cars with children.

INFORMATION:

END



ELSE PRESS RELEASES FROM THIS DATE:

Why we need better drug monitoring

2011-01-11
The use of recombinant activated factor 7 (rFVIIa) despite its potential for adverse events displays the serious shortcomings of Canada's current drug surveillance system, according to a commentary published in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj101842.pdf. Off-label use of this therapy — a blood product — was driven by key physician opinion leaders who thought recombinant factor VIIa could be used to treat or prevent bleeding in patients without hemophilia at risk of death. This shows how promising case ...

Immune cells help heal eye injury in mice

2011-01-11
A paper published online on January 10 in the Journal of Experimental Medicine reports that retinal ganglion cells—neurons in the eye—are rescued by immune cells that infiltrate the mouse retina after eye injury. A group led by Michal Schwartz at the Weizmann Institute detected immune cells called macrophages in the retinas of mice that sustained eye injuries a few days prior. Thanks to their expression of an anti-inflammatory protein, these macrophages dampened injury-induced inflammation and protected the retinal ganglion cells from death. Macrophage arrival also awakened ...

Couch potatoes beware: Too much time spent watching TV is harmful to heart health

2011-01-11
Spending too much leisure time in front of a TV or computer screen appears to dramatically increase the risk for heart disease and premature death from any cause, perhaps regardless of how much exercise one gets, according to a new study published in the January 18, 2011, issue of the Journal of the American College of Cardiology. Data show that compared to people who spend less than two hours each day on screen-based entertainment like watching TV, using the computer or playing video games, those who devote more than four hours to these activities are more than twice as ...

UNC researchers inch closer to unlocking potential of synthetic blood

2011-01-11
A team of scientists has created particles that closely mirror some of the key properties of red blood cells, potentially helping pave the way for the development of synthetic blood. The new discovery – outlined in a study appearing in the online Early Edition of the Proceedings of the National Academy of Sciences during the week of Jan. 10, 2011 – also could lead to more effective treatments for life threatening medical conditions such as cancer. University of North Carolina at Chapel Hill researchers used technology known as PRINT (Particle Replication in Non-wetting ...

Cancer cell survival is not 'miR-ly' dependent on p53

2011-01-11
TITLE: A microRNA-dependent program controls p53-independent survival and chemosensitivity in human and murine squamous cell carcinoma AUTHOR CONTACT: Leif Ellisen Massachusetts General Hospital Cancer Center, Boston, MA, USA Phone: (617)726-4315; Fax: (617)726-8623; E-mail: ellisen@helix.mgh.harvard.edu View this article at: http://www.jci.org/articles/view/43897?key=34ca4a64f929de6d5fea END ...

Transforming skin cells into cartilage

2011-01-11
TITLE: Generation of hyaline cartilaginous tissue from mouse adult dermal fibroblast culture by defined factors AUTHOR CONTACT: Noriyuki Tsumaki Osaka University Graduate School of Medicine, Suita, UNK, JPN Phone: +81-6-6879-3552; Fax: +81-6-6879-3559; E-mail: ntsumaki@dbcb.med.osaka-u.ac.jp View this article at: http://www.jci.org/articles/view/44605?key=631d5aff983c237cf1dc END ...

JCI online early table of contents: Jan. 10, 2011

2011-01-11
EDITOR'S PICK Cancer cell survival is not miR-ly dependent on p53 Squamous cell carcinoma (SCC) is a common type of skin cancer and remains one of the most resistant to available chemotherapies. Many cancer therapeutic strategies are directed at restoring the function of the tumor suppressor gene p53, because when active, cells are more sensitive to the DNA damage induced by chemotherapy. Other proteins related to p53, including p63 and p73, have also been implicated in cancer and cell sensitivity to chemotherapy. Both p63 and p73 are overexpressed in SCC, and are thought ...

Nursing home closures concentrated in poorest areas

2011-01-11
While wealthier people have chosen alternatives to urban nursing homes, the urban poor still depend on them for long-term care. A new study led by researchers at Brown University finds that option is nevertheless slipping away. Between 1999 and 2008, nursing home closures in the United States were concentrated disproportionately in poor, urban and predominantly minority neighborhoods. Overall, the United States lost 5 percent, or 96,902, of its total nursing home beds during the decade, as patients with means sought assisted living or other forms of home and community-based ...

Aggressive care raises Medicare costs in end-stage dementia

2011-01-11
BOSTON—A large proportion of Medicare expenditures for nursing home residents with advanced dementia, a terminal illness, is spent on aggressive treatments that may be avoidable and of limited clinical benefit, according to a new study by the Institute for Aging Research, an affiliate of Harvard Medical School, published in the online version of the Archives of Internal Medicine on Jan. 10, 2011. The study examined Medicare expenditures for 323 nursing home residents with advanced dementia in 22 facilities in the Greater Boston area as part of the Choices, Attitudes, and ...

Hard-to-find fish reveals shared developmental toolbox of evolution

2011-01-11
A SCUBA expedition in Australia and New Zealand to find the rare embryos of an unusual shark cousin enabled American and British researchers to confirm new developmental similarities between fish and mammals. Elephant fish, a relative of sharks, utilize the same genetic process for forming skeletal gill covers that lizards and mammals use to form fingers and toes, researchers at the University of Chicago and the University of Cambridge found. The precise timing of when and where that gene is expressed during embryonic development produces dramatic anatomical differences ...

LAST 30 PRESS RELEASES:

SKKU research team unravels the origin of stochasticity, a key to next-generation data security and computing

Flexible polymer‑based electronics for human health monitoring: A safety‑level‑oriented review of materials and applications

Could ultrasound help save hedgehogs?

attexis RCT shows clinically relevant reduction in adult ADHD symptoms and is published in Psychological Medicine

Cellular changes linked to depression related fatigue

First degree female relatives’ suicidal intentions may influence women’s suicide risk

Specific gut bacteria species (R inulinivorans) linked to muscle strength

Wegovy may have highest ‘eye stroke’ and sight loss risk of semaglutide GLP-1 agonists

New African species confirms evolutionary origin of magic mushrooms

Mining the dark transcriptome: University of Toronto Engineering researchers create the first potential drug molecules from long noncoding RNA

IU researchers identify clotting protein as potential target in pancreatic cancer

Human moral agency irreplaceable in the era of artificial intelligence

Racial, political cues on social media shape TV audiences’ choices

New model offers ‘clear path’ to keeping clean water flowing in rural Africa

Ochsner MD Anderson to be first in the southern U.S. to offer precision cancer radiation treatment

Newly transferred jumping genes drive lethal mutations

Where wells run deep, biodiversity runs thin

Q&A: Gassing up bioengineered materials for wound healing

From genetics to AI: Integrated approaches to decoding human language in the brain

Leora Westbrook appointed executive director of NR2F1 Foundation

Massive-scale spatial multiplexing with 3D-printed photonic lanterns achieved by researchers

Younger stroke survivors face greater concentration, mental health challenges — especially those not employed

From chatbots to assembly lines: the impact of AI on workplace safety

Low testosterone levels may be associated with increased risk of prostate cancer progression during surveillance

Analysis of ancient parrot DNA reveals sophisticated, long-distance animal trade network that pre-dates the Inca Empire

How does snow gather on a roof?

Modeling how pollen flows through urban areas

Blood test predicts dementia in women as many as 25 years before symptoms begin

Female reproductive cancers and the sex gap in survival

GLP-1RA switching and treatment persistence in adults without diabetes

[Press-News.org] Risks associated with secondhand smoke in cars carrying children