(Press-News.org) PITTSBURGH, Feb. 20, 2024 — Buprenorphine, a life-saving medication for opioid use disorder, is far less accessible in geographic areas of the United States with racially and ethnically diverse populations than in predominantly white areas, according to a new study of pre-pandemic data led by health policy scientists at the University of Pittsburgh School of Public Health published today in Journal of Addiction Medicine.
The study is among the first to examine buprenorphine access at the local, sub-county level, and the findings point to lack of access to medications for opioid use disorder as a potential contributing reason why overdose deaths are rising most rapidly among Black Americans and Native Americans.
“The degree is rather striking,” said lead author Coleman Drake, Ph.D., assistant professor in the Department of Health Policy and Management at Pitt Public Health. “Access is substantially better in areas that are very white. When you move to areas with even some racial or ethnic diversity, there is a large decline in the geographic availability of buprenorphine prescribers and prescription fills. In areas that are less than 95 % white, for example, there’s a 45 to 50 % drop.”
The team examined the numbers of buprenorphine prescribers and dispensed buprenorphine prescriptions within geographic regions—ZIP codes and surrounding areas within a 30-minute drive—in 2018.
The more ethnically and racially diverse ZIP codes had 45% to 55% fewer buprenorphine prescribers in urban areas and 62% to 79% fewer prescribers in rural areas. Dispensed prescriptions reflected these inequities, as well, with 51% to 76% fewer dispensed in diverse urban areas and 68% to 87% fewer in diverse rural areas.
Unfortunately, said Drake, efforts leading up to 2018 to increase the number of buprenorphine prescribers have not resulted in equitable access to this treatment. Addressing these disparities will require a two-fold strategy: increasing the number of buprenorphine prescribers in diverse communities and, particularly in urban areas, promoting increased prescribing among those already prescribing the treatment, he said. Additional studies are also needed to determine how more recent changes in provider requirements for prescribing buprenorphine, as well as an increase in telehealth flexibilities, have impacted these health disparities.
Other authors on the study were Dylan Nagy, M.S., of Pitt; Mark K. Meiselbach, Ph.D., Brendan Saloner, Ph.D., and Daniel Polsky, Ph.D., of Johns Hopkins University; Jane M. Zhu, M.D., M.P.P., of Oregon Health & Science University, and Bradley D. Stein, M.D., Ph.D., of RAND Corporation.
This research was supported by the National Institute on Drug Abuse of the National Institutes of Health under the award numbers K01DA051761 and R01DA045800. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
# # #
About the University of Pittsburgh School of Public Health
Founded in 1948, the University of Pittsburgh School of Public Health is a top-ranked institution of seven academic departments partnering with stakeholders locally and globally to create, implement and disseminate innovative public health research and practice. With hands-on and high-tech instruction, Pitt Public Health trains a diverse community of students to become public health leaders who counter persistent population health problems and inequities.
www.upmc.com/media
END
In an editorial, Sethuraman Panchanathan, director of the U.S. National Science Foundation (NSF), calls for the responsible and equitable development of artificial intelligence (AI) and promises to use the agency’s resources to work toward democratizing AI research. NSF spends $800 million on AI research in the public interest each year. Panchanathan summarizes some of the benefits AI can offer to scientific research—from accelerating discovery to automating routine tasks—but emphasizes that AI must be safe and accessible. Toward that end, NSF and its partners launched the National Artificial Intelligence Research Resource ...
Many animals, including apex predators, move in groups. We know this collective behavior is fundamental to the animal’s ability to move in complex environments, but less is known about what drives the behavior because many factors underlie its evolution. Scientists wonder, though, if all these animals share a fundamental drive such as for mating, safety, or perhaps even to save energy.
“The keyword is perhaps,” said Yangfan Zhang, postdoctoral researcher in the Department of Organismic and Evolutionary Biology (OEB) at Harvard, “because no one has actually measured this and compared it directly across all animal groups, mainly ...
One in three police homicides could have been avoided without endangering police or the public, according to a study. Eight percent of all homicides of adult men in the United States are committed by police. Using data from 2008–2017 from the National Officer-Involved Homicide Database, Josh Leung-Gagné compared police homicide rates across the 711 local police departments serving 50,000 or more residents in the United States. One explanation for differing rates of police killings is that some jurisdictions are riskier than others, which necessitates ...
Research participants who read propaganda generated by the AI large language model GPT-3 davinci were nearly as persuaded as those who read real propaganda from Iran or Russia, according to a study. Josh Goldstein and colleagues identified six articles, likely originating from Iranian or Russian state-aligned covert propaganda campaigns, according to investigative journalists or researchers. These articles made claims about US foreign relations, such as the false claim that Saudi Arabia committed to help fund the US-Mexico border wall or the false claim that the US fabricated reports showing that the Syrian government had used chemical weapons. For each ...
The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job knocking out genes to cure hereditary disease. But it's still not possible to insert whole genes into the human genome to substitute for defective or deleterious genes.
A new technique that employs a retrotransposon from birds to insert genes into the genome holds more promise for gene therapy, since it inserts genes into a "safe harbor" in the human genome where the insertion won't disrupt essential genes or lead to cancer.
Retrotransposons, or retroelements, are pieces of DNA that, when transcribed ...
Cycles of a diet that mimics fasting can reduce signs of immune system aging, as well as insulin resistance and liver fat in humans, resulting in a lower biological age, according to a new USC Leonard Davis School of Gerontology-led study.
The study, which appears in Nature Communications on Feb. 20, adds to the body of evidence supporting the beneficial effects of the fasting-mimicking diet (FMD).
The FMD is a five-day diet high in unsaturated fats and low in overall calories, protein, and carbohydrates and is designed to mimic the effects ...
CAMBRIDGE, MA -- Any drug that is taken orally must pass through the lining of the digestive tract. Transporter proteins found on cells that line the GI tract help with this process, but for many drugs, it’s unknown which of those transporters they use to exit the digestive tract.
Identifying the transporters used by specific drugs could help to improve patient treatment because if two drugs rely on the same transporter, they can interfere with each other and should not be prescribed together.
Researchers at MIT, Brigham and Women’s Hospital, and Duke University ...
Published today in Nature Climate Change, the study found that exported used vehicles generate at least 13-53% more emissions per mile than those that are scrapped or on the road in Great Britain. The researchers used mandatory annual vehicle inspections – known as MOT tests – of all 65 million used vehicles on British roads between 2005 and 2021 to compare the pollution and emissions intensity of vehicles exported to those scrapped, destroyed, or driven in Great Britain.
The data revealed substantially higher rates of carbon dioxide and pollution generation in exported vehicles. ...
ROCKVILLE, Md.— Whether you engage in physical activity on a regular basis or one-to-two days a week, both options produce weight loss suggests a new study published in the journal Obesity, The Obesity Society’s (TOS) flagship journal. The study is the first of its kind to examine the association between physical activity patterns and objectively-measured fat tissue mass.
Guidelines from the World Health Organization recommend that adults perform at least 150 minutes per week of moderate physical activity, 75 minutes per week of vigorous physical activity or an equivalent combination of both intensities. ...
People living in the Inuit region of Nunavik in northern Quebec die earlier after a diagnosis of lung cancer than Montreal residents receiving treatment at the same cancer centre, according to new research published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.230682.
All inhabitants of Nunavik are investigated and treated for cancer at the McGill University Health Centre (MUHC) in Montreal, more than 1400 km away from Nunavik hospitals, due to limited resources in the region.
Researchers compared lung cancer survival ...