(Press-News.org) Suicidality hit new record high in U.S. in 2022
New tool was 92% effective at predicting four variables related to self-harm
AI uses a small set of judgment and contextual variables as opposed to big data, and strongly supports the hypothesis of a standard model of mind
EVANSTON, Ill. --- A new assessment tool that leverages powerful artificial intelligence was able to predict whether participants exhibited suicidal thoughts and behaviors using a quick and simple combination of variables.
Developed by researchers at Northwestern University, the University of Cincinnati (UC), Aristotle University of Thessaloniki and Massachusetts General Hospital/Harvard School of Medicine, the system focuses on a simple picture-ranking task along with a small set of contextual/demographic variables rather than extensive psychological data.
The tool was on average 92% effective at predicting four variables related to suicidal thoughts and behaviors.
“A system that quantifies the judgment of reward and aversion provides a lens through which we may understand preference behavior,” said first author Shamal Shashi Lalvani, a doctoral student at Northwestern University. “By using interpretable variables describing human behavior to predict suicidality, we open an avenue toward a more quantitative understanding of mental health and make connections to other disciplines such as behavioral economics.”
The study, which will be published in the journal Nature Mental Health on Thursday, May 9, concludes that a small set of behavioral and social measures play a key role in predicting suicidal thoughts and behaviors. The current work details the components of a tool that could be an app for medical professionals, hospitals or the military to provide assessment of who is most at risk of self-harm.
“It’s reported we have about 20 suicides daily among veterans in the U.S., and a salient number of students. We all can cite statistics to how the American medical system is at a breaking point. I wish we’d had this technology sooner. The data strongly argues it would change outcomes,” said Hans Breiter, contact PI for the study, and a professor in computer science and biomedical engineering at UC.
“People have developed good techniques with big data,” Breiter said, “but we have problems interpreting the meaning of many predictions based on big data. Having a small number of variables grounded in mathematical psychology appears to get around this issue and is needed if current machine learning is ever going to approach the issue of artificial general intelligence.”
Data was collected from surveys completed in 2021 by 4,019 participants ages 18 to 70 across the United States. Identities of participants were protected and not shared with researchers and participants gave informed consent.
Participants were asked to rank a random sequence of 48 pictures on a seven-point like-to-dislike scale of 3 to -3 in six categories: sports, disasters, cute animals, aggressive animals, nature and adults in bathing suits. Researchers also collected a limited set of demographics about age, sex assigned at birth, race or ethnicity, highest education level achieved and handedness.
“The usage of a picture-rating task may seem simple but understanding individual preferences and how one evaluates reward and aversion plays a large role in shaping personality and behavior,” said co-PI for the study and co-senior author Aggelos Katsaggelos, the Joseph Cummings Professor of Electrical and Computer Engineering at McCormick and director of the AI in Multimedia-Image and Video Processing Lab at Northwestern.
“We find that our results in predicting suicidality exceed typical methods of measurement without using extensive electronic health records or other forms of big data,” Katsaggelos said.
Along with the picture ratings, participants completed a limited set of mental health questions and were asked to rank perceived loneliness on a five-point scale.
When the data was plugged into an artificial intelligence system developed by Northwestern and University of Cincinnati, the software was able to predict four measures of suicidal thoughts and behaviors: passive suicidal ideation (desire without a plan); active ideation (current and specific thoughts); planning for suicide; and planning coping strategies to prevent self-harm.
Researchers noted that respondents in other countries could have unique cultural influences that might affect prediction success, although race and gender effect were the least predictive of any measures used. Another potential limitation, the researchers said is the surveys were self-reported rather than through clinical assessments, adding that it’s difficult to see how a prospective study of suicide might be performed. Lastly, the cohort was sampled during the COVID-19 pandemic at a time that has seen higher-than-normal rates of loneliness and self-harm.
END
Understanding how genes are regulated at the molecular level is a central challenge in modern biology. This complex mechanism is mainly driven by the interaction between proteins called transcription factors, DNA regulatory regions, and epigenetic modifications – chemical alterations that change chromatin structure. The set of epigenetic modifications of a cell’s genome is referred to as the epigenome.
In a study just published in Nature Genetics, scientists from the Hackett Group at EMBL Rome have developed a modular epigenome editing platform – a system to program epigenetic modifications at any location in the genome. The system allows scientists to study the impact ...
Aging clocks can measure the biological age of humans with high precision. Biological age can be influenced by environmental factors such as smoking or diet, thus deviating from the chronological age that is calculated using the date of birth. The precision of these aging clocks suggests that the aging process follows a programme. Scientists David Meyer and Professor Dr Björn Schumacher at CECAD, the Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases of the University of Cologne, have now discovered that aging clocks actually measure the increase in stochastic changes in cells. The study ‘Aging clocks based on accumulating stochastic variation’ ...
Background and objectives
Wilms tumor is the most common renal malignancy in children. miR-146a, a highly conserved small noncoding RNA, plays a critical role in various human diseases. Increasing studies have suggested that rs2910164 C>G polymorphism in miR-146a is associated with susceptibility to cancers. However, miR-146a rs2910164 C>G polymorphism influence on Wilms tumor remains unknown. The aim of this study was to evaluate the relationship between miR-146a rs2910164 C>G polymorphism and Wilms ...
BETHESDA, MD. (May 9, 2024) — A simple oral rinse could provide early detection of gastric cancer, the fourth-leading cause of cancer deaths worldwide, according to a study scheduled for presentation at Digestive Disease Week® (DDW) 2024.
“In the cancer world, if you find patients after they've developed cancer, it's a little too late,” said Shruthi Reddy Perati, MD, author and general surgery resident at Rutgers Robert Wood Johnson School of Medicine. “The ideal time to try to prevent ...
The saturated soil conditions predicted to result from increased rainfall in the UK’s upland regions could have a knock-on effect on the ambition to create more woodland in the fight against climate change, a new study has found.
Researchers from the University of Plymouth have spent a number of years exploring how temperate rainforests could be an effective nature-based solution to some of the planet’s greatest challenges.
They have also shown that the UK’s uplands could in future see significantly more annual rainfall than is currently being predicted in national climate models.
In new research, they found that higher soil water levels within areas such ...
A new paper in Oxford Open Climate Change, published by Oxford University Press, indicates that extensive bleaching and deaths are widespread at several major coral reefs around the world. This suggests that climate change has resulted in shifting patterns in ocean circulation. Coral reefs may soon be a thing of the past.
Last year, 2023, was the hottest year in recorded history on land and in the oceans, with dramatic and unexpected temperature increases. The highest excess daily air temperatures recorded in 175 countries, as well the most ...
Citizens are often deeply concerned about how the government manages public finances and taxes. However, understanding government fiscal policy can be complex, leaving citizens without a complete picture of the factors guiding budget decisions. Kyoto City, the ninth most populous city in Japan, has been facing financial difficulties due to declining tax revenues and rising government spending. This has caused citizens to hold negative views about government policies, even though they may not fully understand them.
A study published in the journal International Review of Administrative Sciences ...
BETHESDA, MD. (May 9, 2024) — A new weight-loss treatment could be on the horizon with an innovative endoscopic procedure that ablates (burns) the stomach lining to reduce production of ghrelin, a hormone that triggers hunger, resulting in decreased appetite and significant weight loss, according to a first-in-human trial to be presented at Digestive Disease Week® (DDW) 2024.
The six-month trial involving 10 female patients with obesity resulted in a 7.7% loss of body weight and a reduction of more than 40% in fasting ghrelin levels. Patients reported through validated questionnaires that their hunger was diminished by more than a third. The procedure also caused a 42% reduction ...
BETHESDA, MD. (May 9, 2024) — Health care professionals attending certain smoke-producing endoscopic gastrointestinal procedures, including a procedure that uses electrical current to remove polyps, could be exposed to dangerous toxin levels equivalent to smoking a cigarette during each procedure and face “significant health risks” over their careers, according to a study scheduled for presentation at Digestive Disease Week® (DDW) 2024.
“Surgeons in the operating room have regulations and guidelines to mitigate smoke exposure, but that does not exist for gastrointestinal endoscopy,” said Trent Walradt, MD, a research fellow at Brigham and ...
BETHESDA, MD. (May 9, 2024) — Colorectal cancer incidence has steadily increased among younger people in the U.S. over the last two decades, with the youngest seeing the most dramatic jumps, according to a study scheduled for presentation at Digestive Disease Week® (DDW) 2024. Between 1999 and 2020, the rate of colorectal cancers grew 500% among children ages 10 to 14, 333% among teens aged 15 to 19, and 185% among young adults ages 20 to 24, researchers said.
“Colorectal cancer is no longer considered just ...