An auxiliary CHD diagnostic system based on multi-view and multi-modal transthoracic echocardiograms
2024-05-12
(Press-News.org)
Congenital heart disease (CHD) is one of the most common congenital anomalies worldwide, which brings a heavy health and financial burden to patients. Early CHD screening and treatment can significantly improve children’s prognosis and quality of life. However, inexperienced sonographers often face difficulties in recognizing CHD through transthoracic echocardiogram (TTE) images. An auxiliary CHD screening system that allows inexperienced sonographers and general practitioners to perform TTE in a simple and easy-to-use way, thereby improving the CHD screening rate and scope, is urgently needed.
An Anhui Medical University, National Center for Children's Health and National Research Institute for Family Planning co-team have developed a new CHD detection system to identify the TTE cardiac views, integrate information from various views and modalities, visualize the high-risk region, and predict the probability of the subject being normal, atrial septal defect (ASD), or ventricular septal defect (VSD).
“Although multi-modal and multi-view TTEs pose challenges to exploiting the meaningful features from this high-dimensional data, they contain rich information indicating cardiac status worth mining,” said Wanqing Xie, who led the research. Xie is a professor of biomedical engineering at Anhui Medical University.
The team met the challenge by creating a hierarchical network structure. The model first recognized the two modalities (2D and Doppler TTE) and identified the cardiac views of TTEs: apical four chamber (A4C), subxiphoid long axis view (SXLAX) of two atria, parasternal long-axis view (PSLAX) of the left ventricle, parasternal short-axis view (PSSAX) of aorta, and suprasternal long-axis view (SSLAX). Then, the model embedded the features per view for each modality based on the backbone network ResNet50. After the basic feature embedding module, the model fused the embeddings of five views and then merged the information from two modal TTEs. Finally, the prediction of each subject was calculated from the classifier, and the visualization of high-risk regions for each child was generated using the Grad-CAM strategy.
After the child completed the TTE examination, Xie’s auxiliary CHD diagnostic system automatically analyzed the TTE images and computed the probability of each subject being normal, having ASD, or having VSD. The researchers demonstrated that the model accurately identified the children with CHD by integrating the TTEs with multiple views and modalities. The results suggested that the model has the potential to facilitate and improve widespread screening and the distinguishing of CHD subtypes in children.
END
[Attachments] See images for this press release:
ELSE PRESS RELEASES FROM THIS DATE:
2024-05-12
Researchers at Brigham and Women’s Hospital and Duke University showed that a genetic variant, present in 3-4% of self-identified Black individuals in the U.S., increases the risk for both heart failure and death and contributes to significant decreases in longevity at the population level
A genetic variant carried by 3-4 percent of self-identified Black Americans increases the risk for heart failure and death, contributing to a significant decrease in longevity at the population level, according to a new study led by researchers at Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, and Duke University School of Medicine. The ...
2024-05-12
About The Study: Among self-reported Black individuals, male and female V142I carriers faced similar and substantial risk for heart failure hospitalization, predominantly with reduced ejection fraction, and death, with steep age-dependent penetrance. Delineating the individual contributions of, and complex interplay among, the V142I variant, ancestry, the social construct of race, and biological or social determinants of health to cardiovascular disease merits further investigation.
Corresponding Author: To contact the corresponding author, Scott D. Solomon, M.D., email ssolomon@rics.bwh.harvard.edu.
To access the ...
2024-05-12
The higher the blood sugar level in pregnant women when first diagnosed with diabetes, the higher the risk of complications around and after birth, according to research presented at the 26th European Congress of Endocrinology in Stockholm. For every 5mg/L above the diagnosis threshold, the risk of newborns having low blood sugar levels, or a large birth weight, rises by 9% and 6%, accordingly, while mothers have a 31% higher risk of diabetes after birth. The findings suggest that high-risk women with gestational diabetes should be classified further to limit these complications for both ...
2024-05-12
Women who enter menopause before the age of 40 are more likely to die young, but may lower their risk with hormone therapy, according to research presented at the 26th European Congress of Endocrinology in Stockholm. This long-term Finnish study is the largest carried out on the association between premature menopause and mortality, which highlights the importance of regular medical checkups and appropriate hormone therapy use in these women.
Most women experience menopause between the ages of 45 and 55. However, about 1% of women go through menopause before the age of 40 years, known as premature menopause or ...
2024-05-12
Being asked whether you considered yourself a normal weight, plumper or thinner as a child when attending a doctor’s appointment as an adult might appear like a very strange question to ask, but new research being presented at this year’s European Congress on Obesity in Venice, Italy (12-15 May) suggests that such questions can help identify increased mortality risk in adults living with obesity. The study is by Dr William Johnson, an epidemiology expert based at Loughborough University, UK, and colleagues.
Obesity in adulthood ...
2024-05-12
Viewers bombarded with 52 minutes of junk food advertising every hour.
Young people exposed to influencer and digital game-based marketing consume an additional 37 calories in foods that are high in fat, salt, and sugar after each exposure.
Findings underscore urgent need for digital food marketing polices to protect young viewers.
Food and drink advertisements on videogame livestreaming platforms (VGLSPs) like Twitch are associated with more positive attitudes towards, and purchases and intake of, unhealthy foods that are high in fat, salt and/or sugar (HFSS) like energy drinks among adolescents aged 18 or younger, according ...
2024-05-11
Lisbon, Portugal – 11 May 2024: Heart failure patients who are vaccinated against COVID-19 have an 82% greater likelihood of living longer than those who are not vaccinated, according to research presented today at Heart Failure 2024, a scientific congress of the European Society of Cardiology (ESC).1 Heart Failure is a life-threatening syndrome affecting more than 64 million people worldwide.2
“Patients with heart failure should be vaccinated against COVID-19 to protect their health,” said study author Dr. Kyeong-Hyeon Chun of the National Health Insurance ...
2024-05-11
“Sticks and stones may break my bones,” the old adage goes. “But words will never hurt me.”
Tell that to Eugenia Rho, assistant professor in the Department of Computer Science, and she will show you extensive data that prove otherwise.
Her Society + AI & Language Lab has shown that
Police language is an accurate predictor of violent interactions with Black motorists.
Broadcast media bias and social media echo chambers have put American democracy at risk.
Now, Rho’s ...
2024-05-11
A group of scientists who placed instruments on an ice shelf in Antarctica found that ponds of meltwater were causing the ice to flex and fracture.
Though scientists had predicted the phenomenon, this is the first time it was observed in the field.
The finding raises concerns that, as climate change progresses and more melting occurs, vulnerable ice shelves in Antarctica will collapse—contributing to global sea rise.
“Ice shelves are extremely important for the Antarctic Ice Sheet’s overall health as they act to buttress, or hold back, the glacier ice ...
2024-05-11
Male rats exposed to moderate and repeated stress during adolescence may have reduced fertility, according to research presented at the 26th European Congress of Endocrinology in Stockholm. This study sheds light on the harmful effects that early-life stress has on health and could help to uncover future prevention strategies for children and adolescents.
While hormone levels fluctuate pathologically — especially during life stages such as puberty — stress can cause too much or too little of a hormone in the bloodstream. This hormonal imbalance negatively impacts puberty and the reproduction ...
LAST 30 PRESS RELEASES:
[Press-News.org] An auxiliary CHD diagnostic system based on multi-view and multi-modal transthoracic echocardiograms
