Kids First DRC launches enhanced data portal to strengthen collaborative pediatric research

Announcing the release of the upgraded Kids First Data Resource Portal, designed to streamline big data search and data analysis

2024-06-13

(Press-News.org) The Gabriella Miller Kids First Data Resource Center (Kids First DRC) announces the release of an upgraded Kids First Data Resource Portal, designed to streamline big data search and data analysis. Accessible at portal.kidsfirstdrc.org, the new portal represents a significant advancement in data accessibility, user experience, and collaborative potential with researchers, families, and patients.

Elevated User Experience

Introducing several key enhancements, the new Kids First DRC Portal prioritizes user-centric design to boost the overall research experience. It offers a unified interface, streamlining navigation and accessibility to diverse datasets. Improvements to the updated Kids First DRC Portal include:

Optimized User Interface
Intuitive design for improved navigation and user experience. Advanced Search Functionality
Upgraded search capabilities with added filters and sorting options for easier information retrieval. Customizable Dashboard
Personalized dashboard allowing users to customize their view and access relevant data quickly. Improved Annotations
Predict the consequences of genomic variants on pediatric conditions with new and updated annotations. Searchable Ontologies
Identify patients by condition using searchable disease and phenotype ontologies. Seamless Integration of Diverse Data

The new portal's architecture enables seamless integration of additional genomic datasets beyond Kids First, which may be of interest to investigators studying pediatric conditions. The first is the genomic data from the Children's Brain Tumor Network (CBTN). This holistic approach fosters cross-disciplinary research and enriched insights into the genetic landscape underlying pediatric disease, ultimately improving outcomes for thousands of children.

"It is a pivotal moment for pediatric research to launch the Kids First DRC Portal," says David Higgins, Informatics Program Manager at Kids First DRC, "Our goal is to empower researchers in pediatric oncology and congenital disorders by integrating data seamlessly."

About Kids First Data Resource Center

The Kids First DRC provides high-quality datasets and collaborative tools to accelerate pediatric research. The program fosters data sharing and collaboration to improve outcomes for children with cancer and congenital disorders. Created in 2014, Kids First DRC develops AI-ready data cloud resources to empower research across pediatric conditions, including children's cancer and congenital disorders. Kids First DRC focuses on kids, with genomes of 27,000+ children and their families released to the public. Supported by the NIH Common Fund under award number U2CHL138346.

For more information about the Kids First Data Resource Center and the new data Portal, please visit https://kidsfirstdrc.org.

END

[Attachments] See images for this press release:

Kids First DRC launches enhanced data portal to strengthen collaborative pediatric research 2

ELSE PRESS RELEASES FROM THIS DATE:

Neural balance in the brain is associated with brain maturity and better cognitive ability

2024-06-13

In a world where external and internal stimuli can throw our entire body system off balance, how does our brain prevent itself from becoming overly stimulated? The answer lies in our brain’s ability to maintain the balance of neural excitation (E) and inhibition (I), known as the E/I ratio. By regulating the E/I ratio, the brain prevents over-stimulation and under-stimulation. The E/I ratio of children decreases with healthy development. Children with a lower E/I ratio were observed to have better performance than their peers in cognitive tests such as memory and intelligence, according to studies by researchers from the Centre for Sleep and Cognition ...

Parliamentary members use simpler language on hot days

2024-06-13

Climate change has many widespread and complicated effects on the well-being of people and the planet, and a new study in iScience on June 13 has now added a surprising one to the list. After analyzing the language used in seven million parliamentary speeches around the world, it shows that high temperatures lead to a significant and immediate reduction in politicians’ language complexity. The results suggest that rising heat may come with impacts on our cognitive abilities with real and immediate consequences, the researchers say. The study also showcases ...

Food: Greater gender equality associated with men eating meat more frequently than women

2024-06-13

Men tend to eat meat more frequently than women and the extent of the differences in meat consumption frequency between both genders tend to be greater within countries with higher levels of gender equality and social and economic development, according to a study published in Scientific Reports. The authors suggest that this could be due individuals within these countries having greater opportunities to express food preferences. Christopher Hopwood and colleagues investigated differences in meat consumption between men and women across countries with differing levels of social ...

Antipsychotic medications don’t just stop working below the neck

2024-06-13

PITTSBURGH, June 13, 2024 – New University of Pittsburgh research points to a potential approach to reducing the risk of diabetes associated with widely prescribed antipsychotic medications. The study presents early evidence in support of co-administering antipsychotic medications that block dopamine receptors in the brain alongside drugs that stop antipsychotics from blocking those same receptors in the pancreas. This approach, published today in Diabetes, could limit metabolic side effects, including impaired control over blood sugar, or dysglycemia. This research may also explain why weight control medications, including new neuropeptide drugs Wegovy and Ozempic, may not ...

New study: Outdoor recreation noise affects wildlife behavior and habitat use

2024-06-13

FORT COLLINS, Colo., June 13, 2024 — We may go to the woods seeking peace and quiet, but are we taking our noise with us? A recent study published in the journal, Current Biology, led by scientists from the USDA Forest Service Rocky Mountain Research Station indicates that the answer is yes—and that this noise can trigger a fear response, as if escaping from predators. This new science calls into question whether otherwise high-quality habitat truly provides refugia for wildlife when recreationists are present and underscores the challenges land managers face in balancing ...

Confronting trauma alleviates chronic pain among older veterans

2024-06-13

A new study led by UCLA Health and the U.S. Veterans Affairs Office found chronic pain among older adults could be significantly reduced through a newly developed psychotherapy that works by confronting past trauma and stress-related emotions that can exacerbate pain symptoms. Published in JAMA Network Open on June 13, the study compared the newer therapy, known as emotional awareness and expression therapy, or EAET, to traditional cognitive behavioral therapy, or CBT, in treating chronic pain as well as mental health symptoms such as depression, anxiety and post-traumatic stress disorder symptoms among older veterans. The ...

Pediatric RSV hospitalizations and respiratory support after the pandemic

2024-06-13

About The Study: This cross-sectional study identified a post-pandemic pediatric respiratory syncytial virus (RSV) surge that resulted in markedly increased hospital volumes and advanced respiratory support needs in older children with fewer comorbidities than pre-pandemic seasons. These clinical trends may inform novel vaccine allocation to reduce the overall burden during future RSV seasons. Corresponding Author: To contact the corresponding authors, email Zachary A. Winthrop, M.D. (zachary.winthrop@childrens.harvard.edu), and Melody G. Duvall, M.D., Ph.D. (melody.duvall@childrens.harvard.edu). To ...

Association between cost sharing and naloxone prescription dispensing

2024-06-13

About The Study: The elimination of cost sharing might be associated with increased naloxone dispensing to commercially insured and Medicare patients. Corresponding Author: To contact the corresponding author, Kao-Ping Chua, M.D., Ph.D., email chuak@med.umich.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2024.8378) Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support. Embed this link ...

Giant Magellan Telescope enclosure ready for construction

2024-06-13

PASADENA, CA – June 13, 2024 – The Giant Magellan Telescope and IDOM today announced that the telescope’s enclosure, set to be one of the world’s largest astronomical facilities, passed its final design review and is now ready for construction in Chile. The review marks a major milestone for the telescope, which is now 40% under construction and on track to be operational by the early 2030s. “A team of ten international subject matter experts validated two years of design work by IDOM and the Giant Magellan Telescope. The final design of the enclosure is unique and an important feat of technical management, design, and engineering. We are very grateful ...

More hospitals than ever require staff to get flu shots

2024-06-13

In just a few months, hospitals and health systems nationwide will start working to vaccinate as many staff as possible against the flu. And a new study suggests that more of those hospitals than ever before will require employees to get vaccinated, or seek an exemption. That means more patients could avoid catching the flu while receiving health care -- a key goal for improving patient safety. In all, the new study shows that 96% of the hospitals that serve America’s veterans, and ...

Kids First DRC launches enhanced data portal to strengthen collaborative pediatric research

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: