PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Better understanding cerebral palsy pain types could lead to better treatment

2024-08-07
(Press-News.org) Pain management is an important component of caring for adults with cerebral palsy. 

However, it's the least understood comorbidity in the adult cerebral palsy population. 

A study led by Mark Peterson, Ph.D., M.S., FACSM, a professor of physical medicine and rehabilitation at University of Michigan Health, found that adults living with cerebral palsy had a very high occurrence of pain, with 90% having a pain history and 74% having multiple diagnoses of pain coming from different origins such as the lower back, irritable bowels, joint arthritis and chronic headaches. 

The study compared the prevalence of nociplastic, neuropathic, nociceptive and mixed pain subtypes in adults with cerebral palsy. 

The data described combinations of pain subtypes and to assess their relation to CP subtypes. 

The distribution of pain phenotypes across individual categories found that 86.3% of adults with cerebral palsy experience nociceptive pain, 45.8% experience nociplastic pain and 16.9% experience neuropathic pain. 

Data for the research was collected from a 20% random sample of patients with a CP diagnosis above the age of 18 in the Medicare Fee-for-service research identifiable files from 2008 to 2020. 

“We were not surprised by the extremely high prevalence of pain and pain multimorbidity, as this reflects what most patients report,” said Peterson.

See also: Cerebral palsy patients at higher risk of receiving opioid prescriptions

“This research demonstrates a much higher pain prevalence than previous research, however. We believe our data is more representative of the true pain experience of adults with cerebral palsy.” 

Peterson and his team want their study to shed light on the significance of chronic pain in adults with cerebral palsy to bring better pain management techniques forward. 

“Many adults with cerebral palsy are prescribed opioid medication to treat their pain,” said Peterson. 

“This is not sustainable longterm and can cause numerous complications for patients. It is important to have a better understanding of the pain adults with cerebral palsy experience and how to manage this pain so we can form better treatment methods.” 

“Pain is definitely the most common complaint in our Adults with Cerebral Palsy clinic,” said Edward A. Hurvitz, M.D., a professor of physical medicine and rehabilitation and s co-author on the study. 

“Accurate identification of the pain type and source is critical for proper treatment.” 

Additional authors: Kathryn Ashbaugh, B.S. and Michael O’Leary, B.S. from the Institute for Healthcare Policy and Innovation, Michigan Medicine, University of Michigan, Ann Arbor, MI; Mary Schmidt, D.O., and Heidi Haapala, M.D. from the Department of Physical Medicine and Rehabilitation, Michigan Medicine, University of Michigan, Ann Arbor, MI; and Neil Kamdar, M.A. from the Institute for Healthcare Policy and Innovation, Michigan Medicine, University of Michigan, Ann Arbor, MI, the Center for Population Health Sciences, Stanford University and the Cecil H. Sheps Center for Health Services Research, University of North Carolina. 

Funding: This research was developed in part under a grant from the National Institutes of Health (NIH: #1R21DE032584-01). 

Paper cited: “Pain Phenotypes and Pain Multimorbidity among Adults with Cerebral Palsy: A Nationwide Cohort Study of Medicare Beneficiaries,” Jama Neurology. DOI: 10.1001/jamaneurol.2024.2443  

Sign up for Health Lab newsletters today. Get medical tips from top experts and learn about new scientific discoveries every week by subscribing to Health Lab’s two newsletters, Health & Wellness and Research & Innovation. 

Sign up for the Health Lab Podcast: Add us on Spotify, Apple Podcasts or wherever you get you listen to your favorite shows. 

END


ELSE PRESS RELEASES FROM THIS DATE:

How ribosomes in our cells enable protein folding

2024-08-07
Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature. Ribosomes, the cell’s dedicated molecular machines for protein synthesis, make all proteins in life and do so by piecing together one amino acid building block at a time. As they are being synthesised, these nascent proteins simultaneously attempt to fold while still associated to their parent ribosome, referred to as co-translational protein folding. Understanding how exactly ...

Asthma emergencies spike when allergenic pollen blooms

2024-08-07
ITHACA, N.Y. – A new Cornell University study that tracks how many asthma-related emergency room visits result from pollen in metropolitan areas highlights the importance of knowing local plants and the need for developing science-based pollen forecasts. Such forecasts could alert vulnerable individuals on days when they should consider staying indoors or taking allergy medications ahead of time. “Even though the percent of asthma-related emergency department visits associated with pollen overall was only a few percent on an annual basis, ...

Disaster plant pathology: solutions to combat agricultural threats from disasters

Disaster plant pathology: solutions to combat agricultural threats from disasters
2024-08-07
An often-overlooked component of natural and human-driven disasters is their potential to affect plant health and thus food security at domestic and international scales. Most disasters have indirect effects on plant health through factors such as disruptions to supply chains and damaged infrastructure, but there is also the potential for direct effects from disasters, such as pathogen or vector dispersal caused by floods, hurricanes, and human migration. These occurrences are rarely isolated and instead often occur simultaneously. We have seen examples of the concurrence of disasters in recent history through events such as market disruptions ...

Higher glucose levels worsen prognosis in ischemic stroke patients

2024-08-07
Having higher than usual blood sugar levels at the time of hospital admission for an ischemic stroke significantly increases the risk of a poor functional prognosis or death within three months of the stroke. This is the main conclusion of a study by the Endocrinology and Nutrition Services and the Neurology Department of Hospital del Mar, with researchers from the hospital's Research Institute, the RICORS-ICTUS network, and the CIBER of Diabetes and Associated Metabolic Diseases (CIBERDEM). The study ...

USC Norris Comprehensive Cancer Center to Open Radiation Oncology and Imaging Center in Newport Beach

2024-08-07
LOS ANGELES — USC Norris Comprehensive Cancer Center, part of Keck Medicine of USC, will open a Newport Beach location offering the latest advancements in radiation therapy and diagnostic imaging. The treatment center, which will open in early 2025, will feature cutting-edge cancer technologies that are yet to be available in Orange County, providing new therapeutic options and optimizing patient outcomes.  The new location address is 4590 MacArthur Blvd. in Newport Beach, less than 15 minutes away from USC Norris’ oncology centers in Newport Beach and Irvine. Those centers are staffed by respected oncologists who have served Orange County for decades, ...

MD Anderson Research Highlights for August 7, 2024

2024-08-07
HOUSTON ― The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. Recent developments at MD Anderson include insights into evolutionary cellular adaptations to environmental stressors, potential targets to overcome trouble swallowing in head and neck cancer patients treated with radiation therapy, a promising chemotherapy-free ...

Some e-cigarette chemicals mimic nicotine, possibly bypassing regulation

2024-08-07
DURHAM, N.C. – In what appears to be an effort to bypass public health regulations covering vaping products, some tobacco companies have begun replacing nicotine in e-cigarettes with related chemicals that have similar properties but unknown health effects, Duke Health researchers report. In a research letter appearing Aug. 7 in JAMA, study authors at Duke and Yale University also found that the quantity of these chemicals, known as nicotine analogs, are not accurately disclosed on the packaging. “Vaping products containing nicotine are subject to federal laws that prohibit sales to people  under the age of 21,” said study co-author Sairam V. Jabba, ...

New 400-year temperature record shows Great Barrier Reef is facing catastrophic damage, researchers warn

New 400-year temperature record shows Great Barrier Reef is facing catastrophic damage, researchers warn
2024-08-07
The Great Barrier Reef is under critical pressure, with warming sea temperatures and mass coral bleaching events threatening to destroy the remarkable ecology, biodiversity, and beauty of the world’s largest coral reef, according to new research published today. ‘Highest ocean heat in four centuries places Great Barrier Reef in danger’, published in Nature (8 August), led by University of Wollongong (UOW) Honorary Fellow and University of Melbourne Lecturer Dr Benjamin Henley, provides new evidence of the impact that rising sea surface temperatures ...

Corn’s ‘missing link’

Corn’s ‘missing link’
2024-08-07
Cold Spring Harbor Laboratory (CSHL) has begun to unravel a mystery millennia in the making. Our story begins 9,000 years ago. It was then that maize was first domesticated in the Mexican lowlands. Some 5,000 years later, the crop crossed with a species from the Mexican highlands called teosinte mexicana. This resulted in cold adaptability. From here, corn spread across the continent, giving rise to the vegetable that is now such a big part of our diets. But how did it adapt so quickly? What biological mechanisms allowed the highland crop’s traits to take hold? Today, a potential answer emerges. CSHL Professor and HHMI Investigator Rob Martienssen had ...

Scientists uncover hidden forces causing continents to rise

Scientists uncover hidden forces causing continents to rise
2024-08-07
Scientists at the University of Southampton have answered one of the most puzzling questions in plate tectonics: how and why ‘stable’ parts of continents gradually rise to form some of the planet’s greatest topographic features. They have found that when tectonic plates break apart, powerful waves are triggered deep within the Earth that can cause continental surfaces to rise by over a kilometre. Their findings help resolve a long-standing mystery about the dynamic forces that shape and connect some of the Earth’s most ...

LAST 30 PRESS RELEASES:

Industrial air pollution triggers ice formation in clouds, reducing cloud cover and boosting snowfall

Emerging alternatives to reduce animal testing show promise

Presenting Evo – a model for decoding and designing genetic sequences

Global plastic waste set to double by 2050, but new study offers blueprint for significant reductions

Industrial snow: Factories trigger local snowfall by freezing clouds

Backyard birds learn from their new neighbors when moving house

New study in Science finds that just four global policies could eliminate more than 90% of plastic waste and 30% of linked carbon emissions by 2050

Breakthrough in capturing 'hot' CO2 from industrial exhaust

New discovery enables gene therapy for muscular dystrophies, other disorders

Anti-anxiety and hallucination-like effects of psychedelics mediated by distinct neural circuits

How do microbiomes influence the study of life?

Plant roots change their growth pattern during ‘puberty’

Study outlines key role of national and EU policy to control emissions from German hydrogen economy

Beloved Disney classics convey an idealized image of fatherhood

Sensitive ceramics for soft robotics

Trends in hospitalizations and liver transplants associated with alcohol-induced liver disease

Spinal cord stimulation vs medical management for chronic back and leg pain

Engineered receptors help the immune system home in on cancer

How conflicting memories of sex and starvation compete to drive behavior

Scientists discover ‘entirely unanticipated’ role of protein netrin1 in spinal cord development

Novel SOURCE study examining development of early COPD in ages 30 to 55

NRL completes development of robotics capable of servicing satellites, enabling resilience for the U.S. space infrastructure

Clinical trial shows positive results for potential treatment to combat a challenging rare disease

New research shows relationship between heart shape and risk of cardiovascular disease

Increase in crisis coverage, but not the number of crisis news events

New study provides first evidence of African children with severe malaria experiencing partial resistance to world’s most powerful malaria drug

Texting abbreviations makes senders seem insincere, study finds

Living microbes discovered in Earth’s driest desert

Artemisinin partial resistance in Ugandan children with complicated malaria

When is a hole not a hole? Researchers investigate the mystery of 'latent pores'

[Press-News.org] Better understanding cerebral palsy pain types could lead to better treatment