Finerenone, serum potassium, and clinical outcomes in heart failure with mildly reduced or preserved ejection fraction
JAMA Cardiology
2024-11-17
(Press-News.org)
About The Study: In patients with heart failure with mildly reduced or preserved ejection fraction, finerenone, a nonsteroidal mineralocorticoid receptor antagonist, resulted in more frequent hyperkalemia and less frequent hypokalemia. However, with protocol-directed surveillance and dose adjustment, clinical benefit associated with finerenone relative to placebo was maintained even in those whose potassium level increased to greater than 5.5 mmol/L.
Corresponding Author: To contact the corresponding author, Scott D. Solomon, MD, email ssolomon@rics.bwh.harvard.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamacardio.2024.4539)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamacardiology/fullarticle/10.1001/jamacardio.2024.4539?guestAccessKey=678be14b-d387-47e1-a4e9-b4d11d8b5657&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111724
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[Press-News.org] Finerenone, serum potassium, and clinical outcomes in heart failure with mildly reduced or preserved ejection fraction
JAMA Cardiology
