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New study finds high concentrations of plastics in the placentae of infants born prematurely

2025-01-30
(Press-News.org) UNDER EMBARGO UNTIL: Jan. 30, 2025, 3:30 p.m. MST

Media Contact: Karen Addis, APR, karen@addispr.com, +1 (301) 787-2394

Denver, Colo. ― Microplastics, which are less than 5 millimeters, and nanoplastics, which are invisible to the naked eye, are widespread throughout our environment. Research has shown that exposure to plastics in general is harmful to both the environment and humans.

Now, in a new study to be presented today at the Society for Maternal-Fetal Medicine’s (SMFM) annual meeting, The Pregnancy Meeting™, researchers will unveil findings that suggest that microplastics and nanoplastics have been found in higher concentrations in the placentae of infants born prematurely compared to those born at term.

In collaboration investigators at the University of New Mexico, researchers used highly sensitive mass spectrometry to analyze 175 placentae; 100 placentae collected at term and 75 collected preterm (less than 37 weeks of pregnancy).

“Advanced technology now enables us to accurately measure microplastics in ways we haven’t been able to in the past,” says senior study author Kjersti Aagaard, MD, PhD, MSCI, a maternal-fetal subspecialist and research professor at Boston Children’s Hospital and the HCA Institute. Aagaard also serves as the medical director of the Gulf Coast Division of HCA Healthcare.

Researchers found that the levels of microplastics and nanoplastics were significantly higher in preterm placenta and they were at much greater levels than previously measured in human blood. This led the investigators to conclude that plastics were likely accumulating in the placenta during pregnancy, with a greater exposure and accumulation occurring in cases of preterm birth.

“The finding of higher placental concentrations among preterm births was surprising because it was counterintuitive to what you might expect if it was merely a byproduct of the length of time of the pregnancy,” says the study’s lead author Enrico R. Barrozo, PhD, an assistant professor in the Department of Obstetrics and Gynecology at Baylor College of Medicine and Texas Children’s Hospital in Houston.

“In other words, a preterm delivery not only accumulated more microplastics and nanoplastics in its placenta relative to term, but did so at an earlier time point in the pregnancy,” added Aagaard. “This hints at the possibility that the accumulation plastics could be contributing to the risk and occurrence of preterm birth. When combined with other recent research, this study adds to the growing body of evidence, ranging from heart disease to potentially stroke, that demonstrates a real risk of exposure to plastics on human health and disease.”

The abstract was publisehd in the January 2025 issue Pregnancy, a new open-access journal and the first official journal for the Society for Maternal-Fetal Medicine.

Additional news releases about select SMFM research being presented are posted on AAAS’s EurekAlert (subscription needed) approximately one week in advance of embargo lifting. Embargoes lift on the date and start time of the abstract presentation.

Disclosure Statement

This study was supported by NIH-NICHD (R01HD091731), NSF (#2208903), NIH LRP (NIAID-1L40AI171990-01), pilot grants from MIEHR (#P50MD015496) and CPEH (#P30ES030285), NIEHS (R01ES014639), CMBM (P20GM130422), UNM CTSC (KL2TR001448), and the Superfund Research Program (P42ES027725). Funding agencies had no role in study design, data collection, analysis, or publication.

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About the Society for Maternal-Fetal Medicine

The Society for Maternal-Fetal Medicine (SMFM), founded in 1977, is the medical professional society for obstetricians who have additional training in high-risk, complicated pregnancies. SMFM represents more than 7,000 members who care for high-risk pregnant people and provides education, promotes research, and engages in advocacy to reduce disparities and optimize the health of high-risk pregnant people and their families. SMFM and its members are dedicated to optimizing maternal and fetal outcomes and assuring medically appropriate treatment options are available to all patients. For more information, visit SMFM.org and connect with the organization on Facebook, X, and Instagram. For the latest 2025 Annual Meeting news and updates, follow the hashtag #SMFM25.

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[Press-News.org] New study finds high concentrations of plastics in the placentae of infants born prematurely