PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Opioid prescribing standards changed practices in BC, but with caveats

2025-05-12
(Press-News.org) VIEW EMBARGOED ARTICLE

In an effort to curb misuse of opioids and prevent overdose deaths, the College of Physicians and Surgeons of British Columbia released a legally enforceable practice standard, Safe Prescribing of Drugs with Potential for Misuse/Diversion, in 2016. This document limited prescribing of opioids for chronic noncancer pain (CNCP) with specific prescribing practices that clinicians were obligated to follow.

In research that tested the effects of the 2016 practice standard on prescribing to patients with CNCP, researchers found that its introduction had a marked impact on prescribing practices. Pre-existing declining trends in doses of opioids (measured in morphine milligram equivalents) accelerated, as did declines in high-dose prescribing, coprescribing with hypnotics like benzodiazepines, and prescribing larger supplies of medications. As well, the number of patients who had doses aggressively tapered increased, which can result in improper pain management. The analysis included data on all opioid prescriptions dispensed to community-living adults in BC between October 2012 and March 2020.

“This demonstrates the ability of practice standards to modify physician behaviour but also highlights how misinterpretation can harm patients,” writes Dr. Dimitra Panagiotoglou, associate professor at McGill University, Montréal, Quebec, with coauthors. “Patient groups and physicians affected by standards or guidelines should be consulted before their release to reduce unintended consequences.”

When the 2016 practice standard was replaced in 2018, the downward trends slowed.

“[T]hese findings demonstrate that prescribing guidelines and practice standards can have immediate and long-lasting effects on physician prescribing. Although most of the changes may be positive (e.g., fewer opioids in the community, a reduction in coprescribed benzodiazepine), incorrect interpretation can increase harms for some patients. Aggressive tapering can have downstream consequences, including people resorting to unregulated opioids for pain relief despite their risks,” write the authors.

People living with chronic pain and opioid use disorder (OUD) in Canada are often unable to access evidence-based treatment, which can reduce effectiveness of treatments for OUD, according to a commentary in the same issue.

VIEW EMBARGOED ARTICLE

“Overcoming barriers — such as siloed care for OUD and chronic pain, and restricted access to allied health services that can improve pain management and OUD outcomes — is essential to effectively addressing the needs of patients with comorbid OUD and chronic pain,” writes Dr. Kiran Grant, an emergency medicine resident at the University of British Columbia, Vancouver, BC, with coauthors.

They suggest interdisciplinary approaches, such as including pain management specialists in care, could help improve outcomes for people with chronic pain and OUD.

“The effects of a provincial opioid prescribing standard on opioid prescribing for pain in adults: an interrupted time-series analysis” and “Integrating chronic pain management into care for patients with opioid use disorder” are published May 12, 2025.

END


ELSE PRESS RELEASES FROM THIS DATE:

AI could be the future for preserving marginalized cultures, say experts

2025-05-12
Promising new AI tools are being developed to protect and preserve the cultural traditions and heritage of marginalized or indigenous communities, including language, folklore, oral traditions, and community wisdom. These advances have prompted industry experts to highlight the potential for culturally aware AI systems, which can ensure unique traditions are not only remembered but also shared and reimagined across generations. But to continue this positive trend, tech companies must ensure the AI-based systems they develop are representative and build bridges across cultures, experts ...

Researchers from The University of Warwick warn marginalized young adults in low- and middle-income countries face “growing online abuse”

2025-05-12
A major new international study has found that young adults in low- and middle-income countries who are sex workers, gay men, transgender or living with HIV are facing a surge in online abuse - from harassment and blackmail to the non-consensual sharing of intimate images.   Researchers from The University of Warwick’s Centre for Interdisciplinary Methodologies warn this abuse is becoming increasingly normalised and is moving between online and in-person threats, with most victims having little access to support or justice.  The study — the largest of its kind — focuses ...

Credit ratings are a key check on CEO overconfidence in corporate acquisitions

2025-05-12
Overconfident chief executives and their risky behaviours can be partly restrained through credit ratings, new research finds. Researchers led by Bangor University in Wales in the United Kingdom and other institutions including Heriot-Watt University in Edinburgh, Scotland, Vlerick Business School in Brussels, Belgium and The University of Aberdeen in Scotland found that the creditworthiness of a company can hugely influence how its chief executive behaves – especially during corporate mergers and acquisitions (M&A). The research, which is published in the journal, European Financial Management, is based on data from 916 firms in the United States who were rated by American ...

Can the U.S. develop a strong national science diplomacy strategy?

2025-05-12
In a new editorial in the AAAS publication Science & Diplomacy, Kimberly Montgomery, Director of International Affairs and Science Diplomacy at AAAS, reflects on whether the United States should develop a national science diplomacy strategy amid significant change to U.S. federal policy. Montgomery believes that the Trump administration should develop such a strategy – to help define a vision and direction for the U.S. It should outline how related policies “can advance U.S. diplomatic objectives, including fostering economic growth,” she writes. “And that strategy should detail how it will work with the private ...

Failure to focus on covid suppression led to avoidable UK deaths, says expert

2025-05-11
Early in the covid-19 pandemic, the failure of UK government advisers to follow World Health Organization (WHO) advice and emerging evidence from East Asia that suppression could bring the virus under control quickly led to avoidable UK deaths, argues an expert in The BMJ today. Suppression aims to avoid national lockdowns and maintain economic activity for most of the population by introducing surveillance systems to bring new outbreaks under control quickly, thus reducing the reproductive rate of infection (R0) to below 1 and ...

GLP-1 receptor agonists show anti-cancer benefits beyond weight loss

2025-05-11
New research being presented at this year’s European Congress on Obesity (ECO) in Malaga, Spain (11-14 May) and published in the journal eClinicalMedicine finds that first generation weight-loss medications like liraglutide and exenatide appear to show anti-cancer benefits beyond weight loss. “Our study found a similar incidence of obesity-related cancer among patients treated with first-generation glucagon-like peptide-1 receptor agonists (GLP-1s) and with bariatric surgery over an average of ...

Childhood obesity can have long-term consequences on employment and study prospects, Swedish study finds

2025-05-11
Individuals who lived with obesity as children are less likely to be in work or studying in their mid-20s than their peers, new research being presented at year’s European Congress on Obesity (ECO 2025) has found. They are also more likely to be on long-term sick leave, the Swedish study of the long-term labour market outcomes of childhood obesity found. “Rates of childhood obesity are higher in individuals from lower socio-economic backgrounds than in those from higher socio-economic positions,” explains Dr Emilia Hagman, of the Karolinska Institutet, Stockholm, Sweden. “The reasons for this are complex but one contributing factor may be ...

Bigger bellies in childhood linked to development of metabolic and heart health risk by 10 years old

2025-05-11
New research being presented at this year’s European Congress on Obesity (ECO) in Malaga, Spain (11-14 May) reveals that adverse waist-to-height ratio trajectories (a marker for central obesity) during childhood may increase cardiometabolic and cardiovascular risk at 10 years old. Notably, children with gradually increasing central obesity from birth were more likely to show early signs of metabolic and cardiovascular risk by age 10. This included elevated blood pressure and higher levels of biomarkers linked to systemic inflammation and metabolic dysfunction, ...

Manuel Heitor to share perspectives on the future of research in Europe at launch of EndoCompass

2025-05-11
Endocrine diseases affect millions of people in Europe, yet research into hormone health remains underfunded and fragmented. EndoCompass aims to change this. By identifying key research priorities and knowledge gaps, the roadmap will guide future studies, funding programmes and policy decisions at European and national levels. Although the full publication is still to come, two dedicated sessions at the Joint Congress will offer an exclusive preview: • On Sunday 11 May, a Scientific Symposium will introduce key findings from ...

Five minutes exposure to junk food marketing results in children consuming 130 kcals more per day, regardless of media advertising type

2025-05-10
Exposure to junk food advertisements (relative to non-food) results in children and adolescents  consuming significantly more calories during the day, regardless of the type of media advertising, according to a randomised crossover trial being presented at this year’s European Congress on Obesity (ECO) in Malaga, Spain (11-14 May). The study found that 7–15 year-olds exposed to just 5 minutes of adverts for foods high in saturated fats, sugar, and/or salt (HFSS) consumed on average 130 kcals per day extra, which is equivalent to the calories in two slices of bread. The timely research is presented as many countries across Europe and globally are considering ...

LAST 30 PRESS RELEASES:

Information entropy untangles vortices and flows in turbulent plasmas

Overall survival and quality-of-life superiority in modern phase 3 oncology trials

Not-so-tasty: Plastic particles found in food could harm the body

For heart health, food quality matters more than cutting carbs or fat

Study suggests obesity contributes to anxiety and cognitive impairment

Higher linoleic acid levels linked to lower heart disease and diabetes risk

Dual-target CAR T cell therapy slows growth of aggressive brain cancer

Adding immune checkpoint inhibitor to standard chemotherapy regimen improves outcomes in stage 3 colon cancer, study finds

Diet influences survival after stage iii colon cancer, Dana-Farber study finds

Switch to experimental drug after liquid biopsy detection of breast cancer recurrence improves outcomes

Alliance presents results from phase III ATOMIC trial combining atezolizumab with chemotherapy for patients with stage III dMMR colon cancer at ASCO 2025

Immunotherapy boosts chemotherapy in combating stage 3 colon cancer

AI deciphers plant DNA: language models set to transform genomics and agriculture

Endophytic fungi from halophyte Sesuvium portulacastrum enhance maize growth and salt tolerance

Quality of kids’ diets linked with dad’s eating habits as a teen

Alliance trial shows dual immunotherapy improves progression-free survival in advanced squamous cell skin cancer

Insights from immunotherapy trial inform new approaches to treating advanced skin cancer

Genome breakthrough reveals secrets behind rapid growth and invasiveness of tropical vine Merremia boisiana

Transforming the certification process of 3D-printed critical components

UC Davis clinical trial shows biomarkers hold clue in treating aggressive prostate cancer

UT Health San Antonio researchers discover new links between heart disease and dementia

AADOCR announces new SCADA/Dentsply Sirona Research Award

Mass General Brigham researchers present key findings at ASCO

Student researchers put UTA on national stage

Hertz Foundation and Breakthrough Energy partner to advance climate and energy solutions

New study reveals how tiny insects detect force

New 3D genome mapping technology sheds light on how plants regulate photosynthesis

Dinosaur eggshell study confirms biogenic origin of secondary eggshell units

Transforming immunotherapy design

New book with a global view of men’s experiences with partner violence

[Press-News.org] Opioid prescribing standards changed practices in BC, but with caveats