PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

University of Houston awarded $3M to launch cancer biomarker facility for immunotherapy research

Project to be housed at UH Drug Discovery Institute

2025-05-27
(Press-News.org) Key takeaway:  
The new University of Houston Cancer Immunotherapy Biomarker Core facility will accelerate biomarker discovery, improve immunotherapy targeting and expand research capacity across Texas — enhancing the state's competitiveness in cancer research and ultimately improving patient outcomes.  HOUSTON, May 27 -- As part of a $93 million grant package, the Cancer Prevention and Research Institute of Texas, known for funding groundbreaking projects, has awarded the University of Houston $3 million to set up a Cancer Immunotherapy Biomarker Core. This state-of-the-art facility will offer researchers in Texas the most comprehensive targeted proteomic cancer biomarker screens currently feasible, particularly in the field of cancer biology and immunotherapy.  

UH CIBC will be the first such facility in Texas to offer targeted proteomics, which is the technology that makes it possible to study thousands of proteins at once and will offer its services at a minimized cost partly subsidized by CPRIT funding. 

“Identifying better biomarkers for cancer will accelerate early diagnosis and better prognostication of cancer, better monitoring of disease progression and treatment response possibly leading to the identification of better medications for treating cancer,” said Chandra Mohan, Hugh Roy and Lillie Cranz Cullen Endowed Professor of Biomedical Engineering and project director. “All of these will lead to reduced cancer associated morbidity and mortality.” 

Rather than targeting cancer cells directly, immunotherapy treats cancer by training the immune system to find and attack the cancer cells.  

“Cancer immunotherapy is experiencing a meteoric rise, and this new chapter in oncology demands a new array of biomarkers, including blood and tissue biomarkers that predict who might respond best to immunotherapy, and biomarkers that help researchers identify the best targets for immunotherapy,” said Mohan.  

To meet these needs the CIBC will offer four unique platforms that include a 11,000- plex targeted proteomic screen that allows 11,000 specific proteins to be screened in any single body fluid sample, representing the largest proteomic coverage possible, as well as 21,000-plex protein array platform that allows scientists to assess the specificity of autoantibodies/ligands against the entire human proteome. 

The core is designed to meet these objectives:  

To offer targeted exploratory proteomic technologies for protein biomarker discovery 

To offer targeted exploratory technologies for identifying novel autoantibodies, neoantigens and binding ligands 

To educate and promote the adoption of contemporary proteomic technologies among Texas researchers 

Mohan, an MD/PhD, has over two decades of expertise in engineering diagnostic arrays and using the platforms offered and is a member of the UH Drug Discovery Institute. He has reported novel biomarkers for colorectal, bladder, prostate, stomach and pancreatic cancers. Weiyi Peng, also an MD/PhD, an immunologist and associate professor of biology and biochemistry, will co-lead the CIBC. She directs the Drug Discovery Institute Immunology Core, with more than 100 UH faculty members. Peng has long-standing expertise in immunoassays and has led projects on T cell-mediated anti-tumor immune response pathways using genetic screens and preclinical models.  

"We are thrilled that Drs. Mohan and Peng received this award. The core is dedicated to immunology research, which aligns with our research priorities,” said Claudia Neuhauser, University of Houston vice president for research. “It will add a critical component to our research infrastructure and synergize with the University-wide Drug Discovery Institute that supports immunology research." 

CPRIT is considered a national model for a state-based, voter-approved cancer research and prevention initiative. All CPRIT grant applications undergo rigorous, independent, unbiased, merit-based peer review. 

END


ELSE PRESS RELEASES FROM THIS DATE:

Record-breaking performance in data security achieved with quantum mechanics

2025-05-27
A joint team of researchers led by scientists at King Abdullah University of Science and Technology (KAUST) and King Abdulaziz City for Science and Technology (KACST) has reported the fastest quantum random number generator (QRNG) to date based on international benchmarks. The QRNG, which passed the required randomness tests of the National Institute of Standards and Technology, could produce random numbers at a rate nearly a thousand times faster than other QRNG.   “This is a significant leap for any industry that depends on strong data security,” said KAUST Professor Boon Ooi, who led the study, which is published in Optics Express. KAUST ...

ASCO: MD Anderson’s Christopher Flowers honored for teaching and mentorship

2025-05-27
CHICAGO, MAY 27, 2025 ― Christopher Flowers, M.D., division head of Cancer Medicine and chair of Lymphoma/Myeloma at The University of Texas MD Anderson Cancer Center, will be honored with the Jamie Von Roenn Excellence in Teaching and Mentorship Award at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in recognition of his leadership and commitment to mentoring young oncology professionals. The ASCO Special Awards are the organization’s highest honors and highlight ...

Study: Emotional responses crucial to attitudes about self-driving cars

2025-05-27
PULLMAN, Wash. -- When it comes to public attitudes toward using self-driving cars, understanding how the vehicles work is important—but so are less obvious characteristics like feelings of excitement or pleasure and a belief in technology’s social benefits. Those are key insights of a new study from researchers at Washington State University, who are examining attitudes toward self-driving cars as the technology creeps toward the commercial market—and as questions persist about whether people will readily adopt them. The study, published in the journal Transportation Research, ...

NCSA shapes students’ computing dreams

2025-05-27
Students Pushing Innovation (SPIN) participant Mankeerat Singh Sidhu and National Center for Supercomputing Applications graduate student researcher Hetarth Chopra won first place in the 2025 Cozad New Venture Challenge for Tandemn, an innovative software solution designed to help democratize artificial intelligence computing resources. Tandemn links idle graphics processing units (GPUs) into unified, high-performance networks designed for AI computing. The goal is to lower costs and barriers to GPU access while providing owners with possible users for their underutilized resources. “While everyone talks about ‘democratizing ...

Can AI analogize?

2025-05-27
Can large language models (LLMs) reason by analogy? Some outputs suggest that they can, but it has been argued that these results reflect mimicry of the results of analogical reasoning in the models’ training data. To test this claim, LLM’s have been asked to solve counterfactual problems that are unlikely to be  similar to problems in training data sets. Here is an example: Let’s solve a puzzle problem involving the following fictional alphabet: [x y l k w b f z t n j r q a h v g m u o p d i c s e] Here is the ...

AI aversion in social interactions

2025-05-27
An experimental study suggests that people are less likely to behave in a trusting and cooperative manner when interacting with AI than when interacting with other humans.  Scientists use experimental games to probe how humans make social decisions requiring both rational and moral thinking. Fabian Dvorak and colleagues compared how humans act in classic two-player games when playing with another human to how humans act when playing with a large-language model acting on behalf of another human. Participants played the Ultimatum ...

In dry conditions, locust babies are born with their first lunch

2025-05-27
Locusts have undersized babies—with their first lunch already in their guts—in dry conditions. Desert locusts have two distinct modes—solitary and gregarious—that are behaviorally and visibly different. The insects also live in the Sahara desert, an environment with frequent dry conditions. Koutaro Ould Maeno and colleagues explored how a lack of moisture and the presence of other locusts shift reproductive resource allocation in the insects. In lab experiments, the authors raised locusts in crowds and in isolation. Crowd-reared females produced fewer, larger eggs than females raised in ...

Feedback loops between disease and human behavior can produce epidemic waves

2025-05-27
Epidemics of infectious disease often come in waves, but the causes of these waves aren’t clear, frustrating efforts to predict or mitigate them. Are waves of infection caused by transmission seasonality, viral mutations, implementation of public health interventions, or something else? Claus Kadelka and colleagues model how human behavior, in response to information about disease risk, can create waves. There is frequently a lag between infection prevalence and the information about that prevalence reaching the public. Once ...

How Japan’s older adults adapted to healthcare challenges during the COVID-19 pandemic

2025-05-27
Public healthcare emergencies, such as the COVID-19 pandemic, can drastically disrupt healthcare systems with long-term repercussions. The effects of such healthcare crises are more pronounced in the aging population, who are particularly vulnerable to chronic infections and sudden disruptions in healthcare. The COVID-19 outbreak that emerged in December 2019 quickly spread worldwide, and several emergency measures were urgently implemented to curb its transmission. During the initial phase of the pandemic, stringent measures like social distancing, isolation, and mandatory wearing of masks were implemented. Unfortunately, ...

Chronic renal failure: Discovery of a crucial biomarker

2025-05-27
In a world first, Canadian scientists at the CRCHUM, the hospital research centre affiliated with Université de Montréal, have identified microRNA able to protect small blood vessels and support kidney function after severe injury. For the four million people diagnosed with chronic renal failure in Canada—and millions more abroad—this scientific advancement could have a major impact on early diagnosis and prevention of the disease. Previously, there was no known reliable biomarker for evaluating the health of these capillaries and for developing ...

LAST 30 PRESS RELEASES:

Children and young people are waiting longer than necessary for cancer diagnosis, according to new research

Mental disorders, cardiovascular diseases, smoking, and road injuries among the top causes of death and disability for millions in the ASEAN region

One in three youth with mental health crisis spent over 12 hours in emergency department waiting for psychiatric bed

Rural location and racial segregation drive gaps in primary care access in Virginia

AHRQ’s National Center for Excellence in Primary Care Research (NCEPCR) consolidates primary care research

Decision involvement and trust shape seniors’ willingness to cut back prescriptions

Nonadherence labeling in primary care often results in poorer health outcome: ethical risks of diagnosing nonadherence

Patients and staff identify opportunities for artificial intelligence to improve primary care eVisits

Study examines authorship inequities in global health research published in family medicine journals in high-income countries

Tip Sheet Summaries May/June 2025

Fewer Ontario family physicians provide comprehensive care

Little free library use may improve rural mental health access

Perfumes and lotions disrupt how body protects itself from indoor air pollutants

Overlooked cells might explain the human brain’s huge storage capacity

Employees assigned more complex projects early in their work history had better outcomes later in their careers

Pioneering ADHD researcher reveals biological pathways linking genes to behavior

Mitochondrial DNA mutation accumulation may not be a determining factor in aging

Researchers unveil epigenetic mechanism of cold adaptation in rice

Hitting the right notes to play music by ear

ASH and ISTH publish revised clinical practice guidelines for pediatric venous thromboembolism

Space-to-ground infrared camouflage with radiative heat dissipation

High-speed binary phase-engraved superpixels improve complex light modulation

Herbal medicine for the mind: Traditionally used medicinal plants for memory loss from the Indian subcontinent

Study finds significant declines in maternal mental health across US

Characterizing long COVID symptoms during early childhood

Weight loss in midlife, chronic disease incidence, and all-cause mortality during extended follow-up

Patient-delivered continuous care for weight loss maintenance

HIV drug can improve vision in patients with common diabetes complication, clinical trial suggests

New fuel cell could enable electric aviation

New clinical practice guideline for the surgical management of chronic rhinosinusitis in adults

[Press-News.org] University of Houston awarded $3M to launch cancer biomarker facility for immunotherapy research
Project to be housed at UH Drug Discovery Institute