Does a culturally tailored quality of life intervention benefit Latina breast cancer survivors and caregivers?

Clinical trial results point to the potential of this strategy to lessen survivors’ anxiety and fatigue.

2025-06-02

(Press-News.org) A recent randomized controlled trial assessed the benefits of a group-based intervention that fosters communication and coping skills in a culturally tailored way for Latina breast cancer survivors and their caregivers. The results are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society.

For the trial, investigators randomized 136 Latina breast cancer survivors and 136 caregivers from Washington, D.C., New York, NY, and San Jose, CA, to participate in an 8-session coping and communication intervention that reflects the cultural preferences and values of Latina/o people (70 pairs) or to receive usual care support services through community-based organizations (66 pairs). The intervention was developed by Nueva Vida, Inc., a community-based organization in Washington D.C., and the study was funded by the Patient-Centered Outcomes Research Institute.

Among the patient-caregiver pairs in the intervention group, 71.4% attended at least 5 of the 8 sessions, demonstrating high engagement, with 82% of participants still in the program at 6 months. There were clinically significant improvements in breast cancer survivors’ reports of anxiety and fatigue at 6 months after the intervention compared with reports by breast cancer survivors who used usual community resources; however, after adjusting for potentially influencing factors, the results were not statistically significant.

“Our close collaboration with 4 exceptional community-based organizations for this trial led to our success with recruitment and retention of Latina breast cancer survivors and their caregivers. Future research can seek to replicate our intervention and evaluate the intervention with other groups of breast cancer survivors and their caregivers,” said senior author Kristi D. Graves, PhD, of Georgetown University.

Additional information
NOTE: The information contained in this release is protected by copyright. Please include journal attribution in all coverage. A free abstract of this article will be available via the CANCER Newsroom upon online publication. For more information or to obtain a PDF of any study, please contact: Sara Henning-Stout, newsroom@wiley.com

Full Citation:
“Randomized Trial of a Community-Based, Culturally Tailored Intervention: High Engagement Among Latina Breast Cancer Survivors.” Katarina AuBuchon, Claudia Campos Galvan, Ysabel Duron, Ivis Sampayo, Migdalia Torres, Alejandra Hurtado-de-Mendoza, Charlene Kuo, Christina Rush, Maria Gloria Elliott, Jennie Santiago, Laura A. Logie, Astrid Jimenez, George Luta, and Kristi D. Graves. CANCER; Published Online: June 2, 2025 (DOI: 10.1002/cncr.35842).

URL Upon Publication: http://doi.wiley.com/10.1002/cncr.35842

Author Contact: Karen Teber, Associate Vice President, Strategic Communications, at km463@georgetown.edu, for Georgetown University Medical Center. Laura Logie, PhD, Director of Research, for Nueva Vida, Inc.: research@nueva-vida.org

About the Journal    
CANCER is a peer-reviewed publication of the American Cancer Society integrating scientific information from worldwide sources for all oncologic specialties. The objective of CANCER is to provide an interdisciplinary forum for the exchange of information among oncologic disciplines concerned with the etiology, course, and treatment of human cancer. CANCER is published on behalf of the American Cancer Society by Wiley and can be accessed online. Follow CANCER on X @JournalCancer and Instagram @ACSJournalCancer, and stay up to date with the American Cancer Society Journals on LinkedIn.

About Wiley     
Wiley is one of the world’s largest publishers and a trusted leader in research and learning. Our industry-leading content, services, platforms, and knowledge networks are tailored to meet the evolving needs of our customers and partners, including researchers, students, instructors, professionals, institutions, and corporations. We empower knowledge-seekers to transform today’s biggest obstacles into tomorrow’s brightest opportunities. For more than two centuries, Wiley has been delivering on its timeless mission to unlock human potential. Visit us at Wiley.com. Follow us on Facebook, X, LinkedIn and Instagram.

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Does a culturally tailored quality of life intervention benefit Latina breast cancer survivors and caregivers?

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