Threats of weather disasters for drug manufacturing facilities in the US

JAMA

2025-08-20

(Press-News.org) About The Study: In this nationwide assessment of the frequency with which climate-related disaster events affected counties with U.S. drug production facilities, researchers determined that nearly two-thirds of all facilities were located in counties that experienced at least one disaster declaration. These disaster events posed risks of disruptions to facilities active in all aspects of the supply chain, from active pharmaceutical ingredient manufacture to packaging, disruptions that could be further magnified by the time needed for Food and Drug Administration reinspection of damaged facilities.

Corresponding Author: To contact the corresponding author, Mahnum Shahzad, PhD, email mahnum_shahzad@g.harvard.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2025.13843)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.13843?guestAccessKey=bdee5afd-6fab-4533-bd38-6690b196d993&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=082025

END

ELSE PRESS RELEASES FROM THIS DATE:

New Cleveland Clinic research identifies link between gut microbes and an elevated risk for abdominal aortic aneurysms

2025-08-20

Cleveland:  Cleveland Clinic researchers have discovered a connection between elevated blood levels of TMAO (trimethylamine N-oxide) — a byproduct of gut bacteria digestion of nutrients found in red meat and other animal products — and a higher risk of abdominal aortic aneurysms. The findings, published today in JAMA Cardiology, suggest that TMAO may play a role in the development, progression, and severity of this life-threatening condition, including faster rates of aneurysm expansion and greater risk for needing surgery. “These results suggest targeting TMAO levels may help prevent and treat aneurysmal disease ...

First-of-its-kind supernova reveals innerworkings of a dying star

2025-08-20

An international team of scientists, led by Northwestern University astrophysicists, has detected a never-before-seen type of exploding star, or supernova, that is rich with silicon, sulfur and argon. When massive stars explode, astrophysicists typically find strong signatures of light elements, such as hydrogen and helium. But the newly discovered supernova, dubbed SN2021yfj, displayed a startling different chemical signature. Astronomers long have theorized that massive stars have a layered structure, similar to an onion. The outermost layers predominantly comprise the lightest elements. As the layers move inward, the elements become heavier and heavier until reaching ...

Drought, extreme heat, and intimate partner violence in low- and middle-income countries

2025-08-20

About The Study: In this cross-sectional study of 42 low- and middle-income countries, drought conditions with various durations were associated with increased intimate partner violence risk. Given the increasing extreme events under climate change, there is a pressing need for enhanced initiatives to prevent domestic violence. Corresponding Author: To contact the corresponding author, Pin Wang, PhD, email pinwang@umd.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.27818) Editor’s Note: Please see the article for additional information, ...

Family socioeconomic position and eating disorder symptoms across adolescence

2025-08-20

About The Study: This cohort study using Avon Longitudinal Study of Parents and Children data found that eating disorder symptoms were more common in individuals experiencing socioeconomic deprivation. Potential socioeconomic inequalities in eating disorder presentation and diagnosis in clinical settings require further investigation. Reducing population-level socioeconomic inequalities could also aid eating disorder prevention. Corresponding Author: To contact the corresponding author, Jane S. Hahn, MSc, email Sungmin.hahn.19@ucl.ac.uk. To access the embargoed ...

Blocking brain damage may slow growth of brain cancer

2025-08-20

Blocking brain damage triggered by a glioblastoma, an aggressive brain cancer, may slow the growth of the cancer and allow the brain to keep working better for longer, according to a new study led by UCL (University College London) researchers. The study, published in Nature and funded by the Brain Tumour Charity and Cancer Research UK, looked at glioblastomas in mice. It found that early-stage tumours damaged parts of nerve cells called axons, and that the brain’s natural response to this injury – breaking down and clearing away these damaged axons – accelerated the tumour’s growth. Mice ...

New research could lead to greener, faster metal production

2025-08-20

Most metals found in nature are actually in their oxide forms. To extract those metals to use in critical applications — ranging from infrastructure such as bridges and buildings to advanced technologies like airplanes, semiconductors or even quantum materials — those oxides must be reduced with gases. A new study illuminating how different gases can affect oxide reduction, however, has the potential to revamp scientific understandings and current industrial practices. Hydrogen or carbon monoxide are typically used as reductants, ...

Researchers use electrochemistry to boost nuclear fusion rates

2025-08-20

Using a small bench-top reactor, researchers at the University of British Columbia (UBC) have demonstrated that electrochemically loading a solid metal target with deuterium fuel can boost nuclear fusion rates. Large-scale magnetic confinement fusion—which puts plasmas under extreme temperatures and pressure—is being widely explored as a method for clean energy generation. The experiment published today in Nature takes an entirely different approach—with a more ...

AI learns biological variability to develop a high-performance serum-free culture medium

2025-08-20

Tsukuba, Japan—Cell culture is a foundational technology widely used across fields such as pharmaceutical production, regenerative medicine, food science, and materials engineering. A critical component of successful cell culture is the culture medium—a solution containing essential nutrients that support cell growth. Therefore, optimizing the culture medium for specific applications is vital. Recently, machine learning has become a powerful tool for efficient media optimization. However, the experimental ...

Transforming the tip of a mechanical pencil lead into a high-quality electron beam source

2025-08-20

Tsukuba, Japan—Nanocarbon materials with pointed geometries, such as graphene and carbon nanotubes, are considered promising candidates as sources for field emission electrons. However, their practical application remains limited due to difficulties in controlling the orientation and arrangement of these materials. In this study, the researchers focused on commercially available pencil leads, which contain appropriate amounts of graphite flakes (graphite powder) and are naturally aligned along the axial direction. The fracture surface ...

From Alzheimer’s to AI: how the TReNDS center at Georgia State is advancing brain research

2025-08-20

ATLANTA — The TReNDS Center at Georgia State University has hit a new stride, earning dual NIH R01 grants aimed at tackling Alzheimer’s disease progression and advancing multimodal brain imaging techniques in neuropsychiatric disorders. The awards mark an exceptional year of achievement for the center and its director, Vince Calhoun, who was recently featured in a global special issue on the “State of the Brain” in the journal Aperture Neuro. R01 grants by the National Institutes of Health (NIH) ...

1 in 3 university students surveyed from a Parisian suburb report being unable to access desired food, with this food insecurity associated with academic dropout

Threats of weather disasters for drug manufacturing facilities in the US

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: