High-intensity exercise and hippocampal integrity in adults with cannabis use disorder

JAMA Psychiatry

2025-09-10

(Press-News.org) About The Study: This trial found that a 12-week high-intensity interval training intervention did not improve hippocampal integrity or associated cognitive or mental health impairments while people continued to consume cannabis. However, results indicated that people with cannabis use disorder can engage in regular physical exercise programs and highlighted exercise as a potential strategy to reduce cannabis craving.

Corresponding Author: To contact the corresponding author, Murat Yücel, PhD, email murat.yucel@qimrb.edu.au.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(10.1001/jamapsychiatry.2025.2319)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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High-intensity exercise and hippocampal integrity in adults with cannabis use disorder

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