Home training for cerebellar ataxias

JAMA Neurology

2025-09-14

(Press-News.org) About The Study: In this randomized clinical trial, home high-intensity aerobic training improved ataxia symptoms, fatigue, and aerobic fitness more than dose-matched home balance training among individuals with cerebellar ataxias, a heterogenous group of disorders characterized by progressive disability due to loss of coordination. Individuals in the aerobic group who continued to train regularly maintained benefits at 1 year.

Corresponding Author: To contact the corresponding author, Scott Barbuto, MD, PhD, email sb3779@cumc.columbia.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamaneurol.2025.3421)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Media advisory: This study is being presented as a poster during the annual meeting of the American Neurological Association.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaneurology/fullarticle/10.1001/jamaneurol.2025.3421?guestAccessKey=cd0dc69d-b2f5-401b-9e74-965c42d8a6e4&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=091425

END

ELSE PRESS RELEASES FROM THIS DATE:

Dry eyes affect over half the general population, yet only a fifth receive diagnosis and treatment

2025-09-14

Copenhagen, Denmark: Dry eyes can cause significant discomfort, and the symptoms become more common as we age. However, until now, it was unclear what proportion of the population suffered from the condition, with estimates ranging from 5-50%. In fact, research presented today (Monday) at the 43rd Congress of the European Society of Cataract and Refractive Surgeons (ESCRS) [1], found that more than half of the general population in the USA and Europe experience dry eyes, yet only 20% of European patients and 17% of US patients were diagnosed, and they can wait years for professional help. Dr Piotr ...

Researchers sound warning about women with type 2 diabetes taking oral HRT

2025-09-14

In women with type 2 diabetes (T2D), use of hormone replacement therapy (HRT) skin patches is not associated with a higher risk of blood clots or stroke. However, an increased cardiovascular risk was found for oral HRT, according to a large real-world study being presented at this year’s Annual Meeting of The European Association for the Study of Diabetes (EASD), Vienna (15-19 Sept). Among the findings are an analysis revealing women with T2D who took the oral form of HRT doubled their risk of developing a pulmonary embolism (PE - when a blood clot blocks an artery in the lung) and faced a 21% increased risk of heart disease compared with ...

Overweight and obesity don’t always increase the risk of an early death, Danish study finds

2025-09-14

It is possible to be “fat but fit”, new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) suggests. The study of tens of thousands of people in Denmark found that those with a BMI in the overweight category – and even some of those living with obesity – were no more likely to die during the five years of follow-up than those with a BMI of 22.5-<25.0 kg/m2, which is at the top end of the normal weight range. Individuals with a BMI in the middle and lower parts of the normal ...

Cannabis use associated with a quadrupling of risk of developing type 2 diabetes, finds study of over 4 million adults

2025-09-14

Cannabis use is linked to an almost quadrupling in the risk of developing diabetes, according to an analysis of real-world data from over 4 million adults, being presented at this year’s Annual Meeting of The European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 Sept). Cannabis use is increasing globally with an estimated 219 million users (4.3% of the global adult population) in 2021, but its long-term metabolic effects remain unknown [1]. While some studies have suggested potential anti-inflammatory or weight management properties, others have raised concerns regarding ...

Gestational diabetes linked to cognitive decline in mothers and increased risk of developmental delays, ADHD and autism among children

2025-09-14

A new synthesis of global evidence finds that experiencing gestational diabetes during pregnancy is linked with a decline in intellectual function among mothers, and may increase the risk of neurodevelopmental disorders, including autism spectrum disorder and attention-deficit/hyperactivity disorder (ADHD) in children. The ongoing systematic review and meta-analysis of 48 observational studies involving over 9 million pregnancies, is being presented at this year’s Annual Meeting of The European Association for the Study of Diabetes (EASD), Vienna (15-19 Sept). The authors say that given the increasing prevalence of gestational diabetes ...

Could we use eye drops instead of reading glasses as we age?

2025-09-14

Copenhagen, Denmark: Everybody develops presbyopia as they age – a difficulty in focusing on near objects and text – and often have to resort to reading glasses. However, the solution might be as simple as using special eye drops two or three times a day. A retrospective study of 766 patients presented today (Sunday) at the 43rd Congress of the European Society of Cataract and Refractive Surgeons (ESCRS) [1], found that the majority could read an extra two, three or more lines on the eye chart used for testing near visual acuity (the Jaeger chart) after using specially formulated ...

Patients who had cataracts removed or their eyesight corrected with a new type of lens have good vision over all distances without spectacles

2025-09-14

Copenhagen, Denmark: Patients who have a new type of lens implanted in their eyes during surgery for cataracts or to correct their eyesight have excellent or good vision over distances both near and far, and often no longer need spectacles for reading. Research presented today (Sunday) at the 43rd Congress of the European Society of Cataract and Refractive Surgeons (ESCRS) [1] evaluated outcomes for around 200 patients in 17 sites in Europe and Asia-Pacific who had surgery to implant the TECNIS PureSEETM, a purely refractive extended depth of field (EDF) presbyopia correction Intraocular Lens (IOL). Presbyopia is the condition that affects ...

AI can spot which patients need treatment to prevent vision loss in young adults

2025-09-13

Copenhagen, Denmark: Researchers have successfully used artificial intelligence (AI) to predict which patients need treatment to stabilise their corneas and preserve their eyesight, in a study presented today (Sunday) at the 43rd Congress of the European Society of Cataract and Refractive Surgeons (ESCRS). [1] The research focused on people with keratoconus, a visual impairment that generally develops in teenagers and young adults and tends to worsen into adulthood. It affects up to 1 in 350 people. In some cases, the condition can be managed ...

Half of people stop taking popular weight-loss drug within a year, national study finds

2025-09-13

The new class of anti-obesity drugs, glucagon-like peptide-1 receptor agonists (GLP-1RAs), is proving remarkably effective at helping individuals lose weight. However, a new population-wide study being presented at this year’s Annual Meeting of The European Association for the Study of Diabetes (EASD), Vienna (15-19 Sept) finds that half of adults without diabetes who start taking the weight-loss drug semaglutide in Denmark discontinue treatment within a year. “This level of drop off is concerning because these medications aren’t ...

Links between diabetes and depression are similar across Europe, study of over-50s in 18 countries finds

2025-09-13

The relative increase in odds of an individual with diabetes developing severe symptoms of depression – and vice versa – is the same, regardless of where they live, a study of over-50s in 18 countries in Europe that is being presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) has found. Individuals with depression are more likely to develop diabetes and vice versa. In addition, previous research has shown that the strength of this association depends on the quality of diabetes ...

LAST 30 PRESS RELEASES:

DNA nanospring measures cellular motor power

Elsevier Foundation and RIKEN launch “Envisioning Futures” report: paving the way for gender equity and women’s leadership in Japanese research

AI and the Future of Cancer Research and Cancer Care to headline October 24 gathering of global oncology leaders at the National Press Club: NFCR Global Summit to feature top scientists, entrepreneurs