Antenatal corticosteroids and infectious diseases throughout childhood

JAMA Network Open

2025-10-13

(Press-News.org) About The Study: In this cohort study, exposure to antenatal corticosteroids (ACS) was associated with increased risks of infections in full-term children until age 21. In preterm children born before 34 weeks’ gestation, no association between ACS and infections was found. To minimize the adverse effects of ACS treatment, more stringent criteria for ACS administration and better prediction tools for preterm birth are required.

Corresponding Author: To contact the corresponding author, Rebecca M. Reynolds, PhD, email r.reynolds@ed.ac.uk.

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(doi:10.1001/jamanetworkopen.2025.36809)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

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Antenatal corticosteroids and infectious diseases throughout childhood

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