Prescribing trends of glucagon-like peptide 1 receptor agonists for type 2 diabetes or obesity
JAMA Network Open
2025-10-31
(Press-News.org)
About The Study: This cross-sectional study found an increase in glucagon-like peptide 1 receptor agonist (GLP-1RA) prescriptions, with notable differences across subpopulations by insurance type, sex, and age. Tirzepatide and semaglutide grew the fastest, possibly due to their superior glycemic, weight loss, and guideline-emphasized cardiorenal benefits. Although GLP-1RAs are generally covered for type 2 diabetes (T2D), coverage for obesity is limited (e.g., Medicare excludes anti-obesity drugs). Off-label semaglutide (for T2D) use in the obesity-only group underscores access barriers.
Corresponding Authors: To contact the corresponding authors, email Mohammed K. Ali, MD, MBA (mkali@emory.edu) and Hui Shao, MD, PhD (hui.shao@emory.edu).
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2025.40890)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.40890?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=103125
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About The Study: This cross-sectional study found that frequent use of continuous glucose monitoring (CGM) (greater than 75% sensor wear) was associated with improved glycemic control compared with infrequent or no use of CGM. These findings suggest that clinicians should monitor CGM use at 6 months, identify potential therapeutic obstacles, and encourage continuous use of CGM.
Corresponding Author: To contact the corresponding author, Irl B. Hirsch, MD, email ihirsch@uw.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2025.39278)
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[Press-News.org] Prescribing trends of glucagon-like peptide 1 receptor agonists for type 2 diabetes or obesity
JAMA Network Open
