Psilocybin outside the clinic – public health challenges of increasing publicity, accessibility, and use

JAMA Psychiatry

2025-11-05

(Press-News.org) About The Study: The expanding use of unregulated psilocybin mushrooms, combined with high variability in composition and common co-use with other substances, raises urgent public health concerns. Existing clinical data are insufficient to guide harm reduction or policy. There is a pressing need to pivot from controlled efficacy trials to real-world research on psilocybin use, including public education, potency testing, and age-specific risk assessment.

Corresponding Author: To contact the corresponding author, Kent E. Hutchison, PhD, email kent.hutchison@cuanschutz.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(10.1001/jamapsychiatry.2025.3038)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Psilocybin outside the clinic – public health challenges of increasing publicity, accessibility, and use

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