Psilocybin outside the clinic – public health challenges of increasing publicity, accessibility, and use

JAMA Psychiatry

2025-11-05

(Press-News.org) About The Study: The expanding use of unregulated psilocybin mushrooms, combined with high variability in composition and common co-use with other substances, raises urgent public health concerns. Existing clinical data are insufficient to guide harm reduction or policy. There is a pressing need to pivot from controlled efficacy trials to real-world research on psilocybin use, including public education, potency testing, and age-specific risk assessment.

Corresponding Author: To contact the corresponding author, Kent E. Hutchison, PhD, email kent.hutchison@cuanschutz.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(10.1001/jamapsychiatry.2025.3038)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapsychiatry/fullarticle/10.1001/jamapsychiatry.2025.3038?guestAccessKey=c58a5cb1-5cc8-4df9-9728-ad5b1ef08abb&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110525

END

ELSE PRESS RELEASES FROM THIS DATE:

Parent-teen sexual health communication and teens’ health information and service seeking

2025-11-05

About The Study: In a cross-sectional, nationally representative survey of 522 parent-teen dyads, frequent parent-teen sexual health communication was associated with increased teen self-efficacy for sexual and reproductive health information and service seeking, but this depended on how comfortable and informed their parents felt. These findings suggest that parents must possess accurate information and comfort to discuss sexual health topics. Corresponding Author: To contact the corresponding author, Hannah Javidi, PhD, email hjavidi@ncat.edu. To ...

Two small changes, that may transform agriculture

2025-11-05

"We are one step closer to a greener and climate-friendlier food production." That is the assessment from Kasper Røjkjær Andersen and Simona Radutoiu, both professors of molecular biology at Aarhus University. The two researchers led a new study where they discovered an important key to understanding how we can reduce agriculture’s need for artificial fertilizer. Plants need nitrogen to grow, a nutrient that most crops solely get from fertilizer. Only a few plants, such as peas, clover, and beans, can manage without it. They live in symbiosis ...

New brain atlas offers unprecedented detail in MRI scans

2025-11-05

A new AI-assisted brain atlas that can help visualise the human brain in unprecedented detail has been developed by UCL researchers, in a major step forward for neuroscience and neuroimaging. The human brain comprises hundreds of interconnected regions that drive our thoughts, emotions, and behaviours. Existing brain atlases can identify major structures in MRI scans – such as the hippocampus, which supports memory and learning – but their finer sub-regions remain hard to detect. These distinctions matter because sub-regions ...

Two main gene discovery methods reveal complementary aspects of biology

2025-11-05

The two main approaches for discovering disease genes reveal distinct aspects of biology, a new study shows. While both methods are widely used, the research found that they identify different genes, with major implications for drug development. Publishing online Nov. 5 in Nature, the study revolves around the human genome, which contains thousands of genes that provide instructions for making proteins, as well as regulatory DNA that controls when genes turn on. The new investigation takes a genome-wide ...

Blocking key protein triggers cancer cell self-destruction

2025-11-05

NYU Langone Health researchers found that a type of cell death caused by a buildup of highly reactive molecules suppresses lung tumor growth. The process, called ferroptosis, evolved to let the body signal for self-destruction of cells that are overly stressed for various reasons. This includes cancer cells, but they in turn evolved to have mechanisms that counter ferroptosis so they can continue their uncontrolled growth despite the stress it creates. Published online November 5 in Nature, the new study showed that an experimental treatment blocked the action in cancer ...

Proposed all-climate battery design could unlock stability in extreme temps

2025-11-05

UNIVERSITY PARK, Pa. — Despite lithium-ion (Li) batteries’ role as one of the most widely used forms of energy storage, they struggle to operate at full power in low temperatures and sometimes even explode at high temperatures. Researchers at Penn State, however, have proposed a design that could hold the key to effective and stable power storage in a variety of climates. The research, which was published today (Nov. 5) in Joule, investigated a state-of-the-art Li battery design known as an all-climate battery (ACB). Previous design approaches ...

Princeton’s new quantum chip built for scale

2025-11-05

In a major step toward practical quantum computers, Princeton engineers have built a superconducting qubit that lasts three times longer than today’s best versions. “The real challenge, the thing that stops us from having useful quantum computers today, is that you build a qubit and the information just doesn’t last very long,” said Andrew Houck, leader of a federally funded national quantum research center, Princeton’s dean of engineering and co-principal investigator on the paper. “This is the next big jump forward.” In a Nov. 5 article in the journal Nature, the Princeton team reported their new ...

High risk of suicide after involuntary psychiatric care

2025-11-05

People who have been treated in psychiatric care against their will are at increased risk of taking their own lives after hospital discharge. This is shown by a new study from Karolinska Institutet published in the journal The Lancet Regional Health – Europe. The results highlight a need for follow-up care after discharge. Every year, more than 10,000 people in Sweden receive involuntary inpatient psychiatric care. This compulsory care is provided in cases of serious mental disorder where there is an urgent need for inpatient care, but the person refuses care. A new study now shows that ...

From degradation to restoration: Remote sensing tracks Asia’s struggle for sustainable drylands

2025-11-05

Across Asia's vast drylands, a new study reveals a critical imbalance between degradation and recovery. Researchers analyzed two decades of satellite data and developed an integrated ecohealth-neutrality framework to track how land ecosystems have changed from 2000 to 2020. The findings show that while ecohealth began improving after 2012, degradation still dominates, with about 22% of the region's land (196 million hectares) remains degraded, compared to only 13% (119 million hectares) showing recovery. This 8% “land debt” indicates the fragile balance between human activity ...

Can Israel feed itself? Economic model to rethink food self-sufficiency unveiled

2025-11-05

A new Hebrew University study reveals that while Israel could technically sustain itself through local vegetative food production, the economic price would be staggering. The model shows that complete self-sufficiency would demand massive farming subsidies and major shifts in agricultural output, making it an impractical goal. Instead, the researchers argue, a balanced approach, combining agricultural innovation, diversified import sources, and strategic food storage, offers the most sustainable path ...

Ultra-low doping 0.1(PtMnFeCoNi)/TiO2 catalysts: Modulating the electronic states of active metal sites to enhance CO oxidation through high entropy strategy

Clinical use of nitrous oxide could help treat depression, major study shows

Report reveals potential of AI to help Higher Education sector assess its research more efficiently and fairly

Corporate social responsibility acts as an insurance policy when companies cut jobs and benefits during the times of crisis

Study finds gender gap in knee injuries

[Press-News.org] Psilocybin outside the clinic – public health challenges of increasing publicity, accessibility, and use
JAMA Psychiatry

Psilocybin outside the clinic – public health challenges of increasing publicity, accessibility, and use

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: