Risk-based vs annual breast cancer screening / the WISDOM randomized clinical trial

JAMA

2025-12-12

(Press-News.org) About The Study: In a randomized clinical trial, researchers found risk-based breast cancer screening was as safe as annual screening for detecting advanced cancers but did not reduce breast biopsy rates. Corresponding author Laura J. Esserman, MD, MBA, of the University of California, San Francisco, will present the study at the San Antonio Breast Cancer Symposium.

Corresponding Author: To interview Dr. Esserman, contact UCSF Senior Public Information Representative Elizabeth Fernandez by email Elizabeth.Fernandez@ucsf.edu, desk phone 415-502-6397, or cell phone 415-298-4320.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2025.24784)

Additional materials: An Editorial written by Nancy N. Baxter, MD, PhD, and Kelly-Anne Phillips, MD, of Melbourne, Australia, will publish with the study.

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

About JAMA: JAMA is a peer-reviewed medical journal published by the American Medical Association. As a leading source of clinical and public health information, JAMA is committed to advancing global health through publication of rigorous research, guidelines, and policy statements.

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Risk-based vs annual breast cancer screening / the WISDOM randomized clinical trial

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