Genetic predisposition to excess body weight and survival in women diagnosed with breast cancer

JAMA Network Open

2026-01-13

(Press-News.org) About The Study: In this cohort of nonmetastatic breast cancer survivors, women who were genetically predisposed to having a higher body mass index were at increased risk of all-cause mortality. Targeted lifestyle recommendations to mitigate their genetic predisposition should be considered to lower this risk.

Corresponding Author: To contact the corresponding author, Clara Bodelon, PhD, MS, email clara.bodelon@cancer.org.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2025.53687)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

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Genetic predisposition to excess body weight and survival in women diagnosed with breast cancer

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