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Science 2026-01-27 1 min read

Acupuncture for migraine without aura and connection-based efficacy prediction

JAMA Network Open
About The Study: This trial demonstrated acupuncture’s efficacy for migraine without aura pain relief and functional improvement. Connectome-based predictive modeling identified default mode network and subcortical cerebellum hypoconnectivity as predicting pain relief and subcortical-cerebellum-motor hyperconnectivity as predicting reduced disability, providing a personalized treatment framework.

Corresponding Author: To contact the corresponding author, Lu Liu, PhD, email lululalavictor1985@126.com.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2025.55454)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

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