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Acupuncture for migraine without aura and connection-based efficacy prediction

JAMA Network Open

2026-01-27
(Press-News.org) About The Study: This trial demonstrated acupuncture’s efficacy for migraine without aura pain relief and functional improvement. Connectome-based predictive modeling identified default mode network and subcortical cerebellum hypoconnectivity as predicting pain relief and subcortical-cerebellum-motor hyperconnectivity as predicting reduced disability, providing a personalized treatment framework.

Corresponding Author: To contact the corresponding author, Lu Liu, PhD, email lululalavictor1985@126.com.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2025.55454)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.55454?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=012726

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

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[Press-News.org] Acupuncture for migraine without aura and connection-based efficacy prediction
JAMA Network Open