PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

‘Nudging’ both patients and providers boosts flu vaccine numbers

2026-01-27
(Press-News.org)

PHILADELPPHIA—Patients were 28 percent more likely to get a flu shot when they got a text message reminder and their primary care provider already had an order for the shot waiting, new research from the Perelman School of Medicine showed. The study was published in JAMA Internal Medicine. 

“This is important given the rise in vaccine hesitancy, which has resulted in a downward trend in flu vaccination that coincided with a high rate of hospitalization this flu season,” said the study’s lead author, Shivan Mehta, MD, MBA, MSHP, associate chief innovation officer at Penn Medicine. “Many nudge interventions directed to patients only on vaccinations have shown limited effectiveness in the United States, so we wanted to make sure that we addressed both sides of the exam room: the patient and the clinician.”   

The researchers believe these results might point to some strategies that could help boost how many people get the shot every year for an illness that has hospitalized up to 710,000 people each year since 2010—and killed as many as 52,000 Americans annually. 

Nudging versus standard care 

The study tested several forms of “nudging,” a behavioral science concept that means small tweaks that make the healthiest choices the easiest ones. Patients who were eligible for the vaccine received flu shot reminder texts (or automated voice recordings), had automatic orders for a flu shot waiting for their clinician to approve, and monthly personalized messages were sent to providers that compared their patients’ vaccination rates to their clinician peers. 

More than 52,000 people were randomly assigned to two groups: one that received all of the nudges or a “standard care” control group at either the University of Pennsylvania Health System or the University of Washington’s health system, UW Medicine The standard care team didn’t get any of the nudges and followed the usual path for getting a flu vaccine, which relies largely on the clinician remembering to offer the vaccine based on information in the electronic health records. Researchers found that almost 3,000 more people got flu shots when they were nudged than would have been expected if they got normal care. 

Why nudging patients and clinicians worked 

Mehta and his colleagues are encouraged by their findings, driven mainly by the importance of communication and trust. 

“We think the automatic order encouraged primary care physicians to have a conversation with their patients, and we know these clinicians still have a lot of trust from their communities,” said co-senior author Amol Navathe, MD, PhD, a professor of Medical Ethics and Health Policy, as well as a professor of Health Care Management in the Wharton School.  

The work continues at scale 

The team has replicated their work at Lancaster General Health in the University of Pennsylvania Health System, which serves a rural and suburban patient base that looks somewhat different than the study populations in this study drawn largely from Philadelphia and Seattle. They are still analyzing the results of this replication study.  

Since the work leverages existing tools in the electronic health record along with other available technologies but no additional staffing or human effort, it could be particularly attractive to health systems looking to augment their flu shot efforts.  

“Future interventions could be more successful by complementing the automated communication with clinical staff to engage with patients that are still hesitant, and integrating flu vaccine nudges with other interventions focused on preventive health, like cancer screening,” Mehta said.  

END



ELSE PRESS RELEASES FROM THIS DATE:

How do nature and nurture shape our immune cells?

2026-01-27
LA JOLLA (January 27, 2026)—The COVID-19 pandemic gave us tremendous perspective on how wildly symptoms and outcomes can vary between patients experiencing the same infection. How can two people infected by the same pathogen have such different responses? It largely comes down to variability in genetics (the genes you inherit) and life experience (your environmental, infection, and vaccination history). These two influences are imprinted on our cells through small molecular alterations called epigenetic changes, which shape cell identity ...

Speeding, hard braking reduced in insurance plans that base rates on driving behavior, offer rewards

2026-01-27
Drivers whose car insurance rates are based on data of their driving habits and who then also got tips about improving them were less likely to speed, brake hard, or rapidly accelerate than those who didn’t participate in the program, according to a recent test by a team from the Perelman School of Medicine at the University of Pennsylvania. Their work was published in Accident Analysis & Prevention.  Speeding declined by up to 13 percent, and hard braking and rapid acceleration declined by up to 25 percent. In addition, drivers ...

Shared process underlies oral cancer pain and opioid tolerance

2026-01-27
Epidermal growth factor receptor (EGFR) signaling in the tissue around oral cancers both increases nerve sensitivity and makes opioids less effective, according to new research published in Science Signaling. The findings point to a shared mechanism underlying both oral cancer pain and opioid tolerance—and a possible new treatment strategy for both.  “Repurposing existing cancer drugs that block EGFR may be a promising way to manage oral cancer pain and prevent or reverse opioid tolerance,” said Yi Ye, PhD, associate professor at NYU College of Dentistry and associate ...

Claiming your business page on review platforms can have unintended effects on customer reviews, study shows

2026-01-27
Claiming a business page on an online review platform such as Yelp may result in a sharp decline in ratings and an increase in lengthy, negative customer feedback, according to a study from Florida International University.  The study, led by Jong Youl Lee, assistant professor of information systems and business analytics at FIU’s College of Business, finds that once a business claims its Yelp page, its average rating falls by more than 10%, driven largely by an influx of one-star reviews and a decrease in five-star reviews. The shift is immediate and persistent, lasting more than a year ...

Inflammation and autoimmune-like dysfunction may play a role in heart failure

2026-01-27
HERSHEY, Pa. — When the heart’s muscle is weakened or injured due to a heart attack, it can make it hard for the heart to pump enough blood to meet the body’s needs. Over time, it can lead to heart failure, where the heart’s function drops below 40%. The condition affects an estimated 6.7 million people over the age of 20 in the United State, according the Centers for Disease Control and Prevention. Approximately 50% of patients with heart failure die within five years ...

How too much of a good thing leads to neurodegenerative disease

2026-01-27
When it comes to neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and certain forms of dementia, researchers have known that protein quality control and damage to the nuclear pore are key players. However, how the two are connected has not been clear. Researchers at Baylor College of Medicine and their colleagues have now identified the mechanism that links the two. The findings are published in the latest edition of Neuron. The nuclear pore, the largest protein complex in the cell, is made up of roughly 30 different proteins. It forms a tightly regulated channel, ...

UH psychologist explores reducing anxiety among survivors of sexual assault

2026-01-27
A psychologist at the University of Houston is providing guidance to improve the mental health of victims of sexual violence, recognized by major health organizations as a public health crisis with serious implications on victims’ physical, mental and reproductive health.   Michael Zvolensky, Hugh Roy and Lillie Cranz Cullen Distinguished University Professor of psychology, led a team examining how the violence of a sexual assault can lead to a higher risk of lifelong challenges from post-traumatic stress disorder to alcohol use disorder. His findings are published in the Journal of Nervous and Mental ...

Project seeks to develop retinal screening for Alzheimer’s

2026-01-27
The human eye may literally become a window revealing the earliest signals of Alzheimer’s disease, thanks to a new federally funded research initiative at Oregon Health & Science University. The new five-year, $3.3 million award will enable OHSU scientists to develop an eye drop specially designed to detect the fluorescent signal of a protein associated with Alzheimer’s. Combined with the use of a noninvasive scanner, the research project could result in a low-cost, widely accessible screening tool to catch the earliest stage of the disease. “We’re looking for early-stage patients who don’t have ...

Mount Sinai study finds antibody-producing immune cells can help shape cancer immunotherapy

2026-01-27
NEW YORK, (January 27, 2026) – Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps explain why some cancer patients benefit from immunotherapy while others do not. In a study published in the January 27 online issue of Nature Medicine (DOI 10.1038/s41591-025-04177-6), the researchers found that antibody-producing immune cells called IgG1 plasma cells play a key role in helping patients respond to PD-1 immune checkpoint inhibitors. PD-1 immune checkpoint inhibitors are a type ...

ACMG announces 2026 Medical Genetics Awareness Week celebrating professionals “making a difference together”

2026-01-27
The American College of Medical Genetics and Genomics (ACMG) announced today that the eighth annual Medical Genetics Awareness Week, sponsored by MyOme, will be held March 10–14, 2026, inviting the public, health professionals, patients, and policymakers to learn more about one of the most rapidly advancing and impactful fields in modern medicine. Medical genetics plays a central role in today’s healthcare, guiding the diagnosis of rare diseases, informing cancer risk, shaping newborn screening, and enabling precision treatment ...

LAST 30 PRESS RELEASES:

One-third of Americans making financial trade-offs to pay for healthcare

Researchers clarify how ketogenic diets treat epilepsy, guiding future therapy development

PsyMetRiC – a new tool to predict physical health risks in young people with psychosis

Island birds reveal surprising link between immunity and gut bacteria

Research presented at international urology conference in London shows how far prostate cancer screening has come

Further evidence of developmental risks linked to epilepsy drugs in pregnancy

Cosmetic procedures need tighter regulation to reduce harm, argue experts

How chaos theory could turn every NHS scan into its own fortress

Vaccine gaps rooted in structural forces, not just personal choices: SFU study

Safer blood clot treatment with apixaban than with rivaroxaban, according to large venous thrombosis trial

Turning herbal waste into a powerful tool for cleaning heavy metal pollution

Immune ‘peacekeepers’ teach the body which foods are safe to eat

AAN issues guidance on the use of wearable devices

In former college athletes, more concussions associated with worse brain health

Racial/ethnic disparities among people fatally shot by U.S. police vary across state lines

US gender differences in poverty rates may be associated with the varying burden of childcare

3D-printed robotic rattlesnake triggers an avoidance response in zoo animals, especially species which share their distribution with rattlers in nature

Simple ‘cocktail’ of amino acids dramatically boosts power of mRNA therapies and CRISPR gene editing

Johns Hopkins scientists engineer nanoparticles able to seek and destroy diseased immune cells

A hidden immune circuit in the uterus revealed: Findings shed light on preeclampsia and early pregnancy failure

Google Earth’ for human organs made available online

AI assistants can sway writers’ attitudes, even when they’re watching for bias

Still standing but mostly dead: Recovery of dying coral reef in Moorea stalls

3D-printed rattlesnake reveals how the rattle is a warning signal

Despite their contrasting reputations, bonobos and chimpanzees show similar levels of aggression in zoos

Unusual tumor cells may be overlooked factors in advanced breast cancer

Plants pause, play and fast forward growth depending on types of climate stress

University of Minnesota scientists reveal how deadly Marburg virus enters human cells, identify therapeutic vulnerability

Here's why seafarers have little confidence in autonomous ships

MYC amplification in metastatic prostate cancer associated with reduced tumor immunogenicity

[Press-News.org] ‘Nudging’ both patients and providers boosts flu vaccine numbers