(Press-News.org)
Embargoed for release: Wednesday, Feb. 18, 2026, 11:00 AM ET
Key points:
Broad spiritual practices, ranging from attending religious services to meditation to prayer, were associated with a 13% reduced risk of hazardous drug and alcohol use, according to a meta-analysis. The greatest reduction (18%) was seen among individuals attending religious services at least once per week.
The meta-analysis is the first of its kind to synthesize and comprehensively estimate how dangerous substance use is impacted over time by spirituality.
According to the researchers, the findings carry potential for individuals who find spirituality important in other aspects of their lives to also use it as a resource in their relationship with drugs and alcohol. Clinicians and communities can also use these findings to consider broader strategies for addiction prevention and care.
Boston, MA—Individuals who engaged in spirituality were significantly less likely to exhibit hazardous use of alcohol, tobacco, marijuana, and illicit drugs, according to a new meta-analysis led by researchers at Harvard T.H. Chan School of Public Health. The meta-analysis is the first of its kind to synthesize and comprehensively estimate associations between harmful or hazardous substance use and spirituality—considered any practice, religious or otherwise, through which an individual finds ultimate meaning, purpose, and connection to something greater than themselves.
“Our findings indicate that spirituality may be protective against substance misuse, one of the biggest public health challenges of our time,” said lead author Howard Koh, Harvey V. Fineberg Professor of the Practice of Public Health Leadership. “For many individuals and families, using spirituality as a resource—whether that be attending religious services, meditating, praying, or seeking others forms of spiritual comfort—may be an avenue to enhance their health.”
The study will be published Feb. 18, 2026, in JAMA Psychiatry.
Of more than 20,000 spirituality and health studies published in the 21st century (2000-2022), the researchers identified 55 that fit their criteria for rigor, including large cohorts and longitudinal design. They analyzed the results of these studies, which collectively followed more than half a million people over time, to understand the overall relationship between spirituality and alcohol and drug use.
The meta-analysis found that broad spiritual practices, including spiritual and religious community involvement, attending religious services, meditation, and prayer, reduced individuals’ risk of dangerous alcohol and drug use by 13%. This reduction was greater (18%) among individuals attending religious services at least once per week. The results were consistent across all of the drug categories studied (alcohol, tobacco, marijuana, and illicit drugs).
“Meta-analyses of such longitudinal studies on spirituality and health are rare. This is a sort of once-in-a-decade advance,” said senior author Tyler VanderWeele, John L. Loeb and Frances Lehman Loeb Professor of Epidemiology. “The consistency of the results across all the studies was striking, with all but a few—including over a dozen studies conducted outside of the U.S.—showing a protective, not detrimental, effect.”
According to the researchers, the findings carry potential not just for individuals, but also for clinicians caring for patients at risk of or struggling with substance misuse and communities working to address substance misuse epidemics.
For example, the researchers wrote that clinicians could ask patients about the role of spirituality in their lives and prompt those who find it important to consider spiritual practices or community participation. Moreover, public health organizations and spiritual or religious communities could join forces to provide more resources and opportunities that help address the factors often driving substance misuse, such as stress, loneliness, and loss of meaning.
Article information
“Spirituality and harmful or hazardous alcohol and other drug use: A meta-analysis of longitudinal studies,” Howard K. Koh, Donald E. Frederick, Tracy A. Balboni, Samantha M. O’Reilly, John F. Kelly, Keith Humphreys, Michael Botticelli, Maya B. Mathur, Constantine S. Psimopoulos, Katelyn N.G. Long, Tyler J. VanderWeele, JAMA Psychiatry, February 18, 2025, doi: 10.1001/jamapsychiatry.2025.4816
The study was supported by the Templeton Religion Trust (grant 2022-30967) and the Lee Family Fund.
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Harvard T.H. Chan School of Public Health is a community of innovative scientists, practitioners, educators, and students dedicated to improving health and advancing equity so all people can thrive. We research the many factors influencing health and collaborate widely to translate those insights into policies, programs, and practices that prevent disease and promote well-being for people around the world. We also educate thousands of public health leaders a year through our degree programs, postdoctoral training, fellowships, and continuing education courses. Founded in 1913 as America’s first professional training program in public health, the School continues to have an extraordinary impact in fields ranging from infectious disease to environmental justice to health systems and beyond.
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Corresponding Author: To ...
About The Study: This meta-analysis synthesized data from 55 published longitudinal studies on spirituality and harmful or hazardous alcohol and other drug use risk and documented a significant protective association. The results of this study have implications for clinicians and communities regarding future strategies for alcohol and other drug use prevention and recovery.
Corresponding Author: To contact the corresponding author, Howard K. Koh, MD, MPH, email hkoh@hsph.harvard.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(10.1001/jamapsychiatry.2025.4816)
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