(Press-News.org) On International Women's Day (8th March), the European Society of Cardiology (ESC) is calling for action to reduce the gender disparities that are currently resulting in women receiving second rate cardiovascular (CV) care. Studies published online today in the European Heart Journal (EHJ), ¹ ² the official journal of the ESC, show a persistent under-utilisation of guideline recommended treatments for heart disease in women compared to men.
"The ESC wants to raise awareness, among both cardiologists and the public, that women still are not receiving equal access to medical treatments and also are not being represented sufficiently in clinical trials," says Marco Stramba Badiale, an ESC spokesman on women's issues from IRCCS Istituto Auxologico Italiano (Milan, Italy). "The problem is that despite female gender being associated with worse CV outcomes there are still major misconceptions among both health professionals and the public that cardiovascular disease (CVD) isn't as serious in women as men."
Data from the World Health Organisation (WHO) show that CVD in Europe accounts for 55% of deaths in women compared to just 43% of deaths in men. While breast cancer - perhaps the most feared illnesses among women - is responsible for only 3% of female deaths. Moreover, recent data from the National Health and Nutrition Examination Surveys (NHANES) looking at tends in midlife coronary heart disease risk show over the past two decades the prevalence of myocardial infarction (MI) has increased in women aged 35 to 54 years, while declining in men of the same age.
"It's very important that physicians are aware that coronary artery disease (CAD) is a frequent disease among women, that gets more common as they get older," says Thomas Lüscher, editor of the EHJ, who has brought together a special issue exploring CV issues facing women.
The studies published in the themed issue raise particular concerns that women are being prescribed fewer drugs than men. "We were shocked to find that even after infarction - the most dramatic cardiac situation we envisage - there's still a dramatic under-utilisation of drugs in women," says Prof. Thomas F. Lüscher, from University Hospital Zurich (Switzerland). "These issues need to be urgently corrected to ensure that women get equal access to state of the art treatments as men."
In the first EHJ study ¹, published online today, cardiologists from the University of Bologna (Bologna, Italy), and the University of Toronto (Toronto, Ontario, Canada), analysed the medical details of 4471 men and 2087 women who had experienced an acute coronary syndrome (heart attack) between 1999 and 2003. The details (which included 23 clinical variables) were recorded on the Canadian Registry of ACS I and I. Results show that women were less likely to:
Receive beta-blocker: 75.76 % of women received beta blockers in comparison to 79.24% of men (P END
International Women's Day provides a 'red alert' for women's hearts
2011-03-08
ELSE PRESS RELEASES FROM THIS DATE:
Young adults with chronic illnesses have poorer educational, vocational and financial outcomes
2011-03-08
Most young adults who grow up with chronic illness graduate high school and have employment, but those with cancer, diabetes, or epilepsy are significantly less likely than their healthy peers to achieve important educational and vocational milestones, according to a report in the March issue of Archives of Pediatrics and Adolescent Medicine, one of the JAMA/Archives journals.
"In the United States, despite the variation in estimates, it is generally accepted that as many as 12 percent of children have special health care needs, including physical and emotional problems," ...
Use of interactive digital exercise games by children can result in high level of energy expenditure
2011-03-08
Middle school-aged children who participated in interactive digital gaming activities that feature player movement (exergaming), such as dancing or boxing, increased their energy expenditure to a level of moderate or vigorous intensity, according to a report posted online today that will appear in the July print issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.
"The prevalence of overweight children and adolescents has increased drastically over the past several decades. This increase is troubling given the potentially numerous ...
Study examines prevalence of eating disorders among adolescents
2011-03-08
Eating disorders are prevalent in the general U.S. adolescent population and are associated with other psychiatric disorders, role impairment, and suicidality, according to a report posted online today that will appear in the July print issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
Although the lifetime prevalence estimates of eating disorders from population-based studies of adults are relatively low, their severity and dramatic effects have been repeatedly demonstrated through elevated rates of impairment, medical complications, other illnesses, ...
Study examines prevalence and severity of bipolar disorder worldwide
2011-03-08
Despite international variation in prevalence rates of bipolar spectrum disorder, the severity and associated disorders are similar and treatment needs are often unmet, especially in low-income countries, according to a report in the March issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
"Bipolar disorder (BP) is responsible for the loss of more disability-adjusted life-years than all forms of cancer or major neurologic conditions such as epilepsy and Alzheimer disease, primarily because of its early onset and chronicity across the life span," ...
Psychosocially hazardous neighborhoods associated with worse cognitive function in some older adults
2011-03-08
Residing in a psychosocially hazardous neighborhood is associated with worse cognitive function in older age for persons with the apolipoprotein E ε4 allele (an alternative form of the gene), according to a report in the March issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
"A prominent genetic factor of relevance to cognitive decline is the ε4 variant of the apolipoprotein E (APOE) gene, a strong predictor of increased risk and earlier onset of Alzheimer disease," the authors write as background information in the article. Apolipoprotein ...
Ohio State study: Targeted ovarian cancer therapy not cost-effective
2011-03-08
COLUMBUS, Ohio – An analysis conducted by Ohio State University cancer researchers has found that adding the targeted therapy bevacizumab to the treatment of patients with advanced ovarian cancer is not cost effective.
The findings comparing the relative value of various clinical strategies will be published online March 7 in the Journal of Clinical Oncology.
The researchers performed a cost-effectiveness analysis looking at a clinical trial conducted by the Gynecologic Oncology Group (GOG) studying the use of bevacizumab along with standard chemotherapy for patients ...
Genetic makeup and duration of abuse reduce the brain's neurons in drug addiction
2011-03-08
UPTON, NY — A study conducted at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory demonstrated that drug addicted individuals who have a certain genetic makeup have lower gray matter density – and therefore fewer neurons – in areas of the brain that are essential for decision-making, self-control, and learning and memory.
Nelly Alia-Klein, a study coauthor who is a Brookhaven Lab medical scientist, said, "This research shows that genes can influence the severity of addiction. The results suggest that addicted individuals with low MAOA [monoamine oxidase ...
Clustering gene expression changes reveals pathways toward glaucoma prevention
2011-03-08
Glaucoma is the second-most common cause of blindness in the US, and occurs due to loss of retinal ganglion cells and degeneration of the optic nerve. Although it is known that high levels of pressure within the eye predispose individuals to the development of glaucoma, the molecular mechanisms involved are poorly defined.
In new research from The Jackson Laboratory in Bar Harbor, Maine, Simon John and colleagues analyzed gene expression patterns in the retina and optic nerves of mice that develop age-related glaucoma. Using a method that involved the clustering of ...
Protecting ecosystems, pollution remediation goals of research at UH
2011-03-08
HOUSTON, March 7, 2011 – Cleaning up pollution, protecting soil from erosion and maintaining species-rich ecosystems are some of the goals of a computational ecology project by a University of Houston (UH) scientist and his team. Published recently in a top journal, the work sheds light on a new method to speed up research in the ecology of plants.
Marc Garbey, a professor of computer science and mathematics at UH, and his fellow researchers describe these findings in a paper titled "Large scale parameter study of an individual-based model of clonal plant with volunteer ...
2 proteins play key roles in Burkitt's lymphoma
2011-03-08
Burkitt's lymphoma is one of the most aggressive tumors affecting humans. Multiple alterations in genes that regulate cell proliferation rate explain its aggressive behavior.
A new study reveals new molecular insight into the understanding and treatment of Burkitt`s lymphoma. The new finding concentrates on a genetic locus -- a piece of DNA with one or more genes which is the specific location of a gene or DNA sequence on a chromosome -- called INK4a/ARF locus. This locus encodes two important tumor suppressor genes, p16 and p14, and is usually inactivated in human tumors ...