PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Study links obesity to increased risk of developing postoperative infection following colon surgery

2011-05-17
(Press-News.org) Obese patients appear to have a significantly increased risk of developing a surgical site infection after colectomy (procedure involving either partial or full removal of the colon), and the presence of infection increases the cost associated with the procedure, according to a report published online today that will appear in the September issue of Archives of Surgery, one of the JAMA/Archives journals.

Surgical site infection (SSI) is considered to be one of the best available measures of quality in surgery, and health care centers are starting to be financially penalized when SSI occurs, according to the authors. However, risk factors for SSI, of which the most common is obesity, are not considered in pay-for-performance models, the authors write as background information in the article.

"We chose to study colectomy as a standardized procedure because the risk of SSI following this procedure is known to be greater than that following other abdominal procedures," writes Elizabeth C. Wick, M.D., of the Johns Hopkins School of Medicine, Baltimore, and colleagues who evaluated SSI rates among obese and non-obese colectomy patients using data collected from claims from members of eight different Blue Cross Blue Shield (BCBS) insurance plans.

The authors identified 7,020 patients who were between 18 and 64 years of age and who underwent either a segmental or total colectomy for colon cancer, diverticulitis or inflammatory bowel disease between January 1, 2002 and December 31, 2008. Among these patients, 1,243 were identified as obese (defined as having a body mass index [BMI] greater than or equal to 30) and 5,777 were classified as non-obese.

The overall rate of SSI was 10.3 percent, with obese patients experiencing a higher rate of SSI compared to non-obese patients (14.5 percent vs. 9.5 percent). Obesity was the strongest predictor of SSI after adjusting for laparoscopy, diagnosis, sex and age, with obese patients experiencing a 60 percent increased odds of SSI compared to non-obese patients.

The mean (average) cost of colectomy was $16,399, with the average cost for obese patients approximately $295 more than that of non-obese patients. On average, developing a postoperative SSI was associated with increased cost of the procedure (average total cost of colectomy was $31,933 in patients with infection versus $14,608 in patients without infection), increased length of hospital stay (average of 9.5 days vs. 8.1 days), and a significantly higher rate of hospital readmission (27.8 percent vs. 6.8 percent).

"We conclude that patients undergoing colorectal surgery who develop SSIs, many of whom are obese, tax the health care system," the authors write. "Pay-for-performance policies in surgery should account for the increased risk of infection and cost of caring for this population. Failure to consider these differences could lead to perverse incentives that may penalize surgeons who care for obese patients and may even affect obese patients' access to colorectal surgery."

### (Arch Surg. Published online May 16, 2011. doi:10.1001/archsurg.2011.117. Available pre-embargo to the media at www.jamamedia.org.)

Editor's Note: The data set in this study was originally created for a different research project on patterns of obesity care within selected BCBS plans. The previous research project (but not the current study) was funded by unrestricted research grants from Ethicon Endo-Surgery, Inc (a Johnson & Johnson company), Pfizer, Inc., and GlaxoSmithKline. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

To contact Elizabeth C. Wick, M.D., call Stephanie Desmon at 410-955-8665 or e-mail sdesmon1@jhmi.edu.

For more information, contact JAMA/Archives Media Relations at 312/464-JAMA (5262) or e-mail mediarelations@jama-archives.org.


ELSE PRESS RELEASES FROM THIS DATE:

Patients referred to dermatologists skin lesions evaluations also found to have other skin cancers

2011-05-17
Among patients referred by non-dermatologists to dermatologists for evaluation of skin lesions suspected of being malignant, only apparently one-fifth were found to be cancerous, although dermatologists identified and biopsied other incidental lesions, approximately half of which were malignant, according to a report in the May issue of Archives of Dermatology, one of the JAMA/Archives journals. "More than one million skin cancers are diagnosed annually in the United States , with one in five Americans developing skin cancer during their lifetime," the authors write as ...

Reminding surgical staff of phlebotomy costs appears to affect utilization

2011-05-17
Surgical house staff and attending physicians who are reminded about the charges for ordering daily blood drawing for routine blood work appear to reduce the amount of routine blood tests ordered and the charges for these laboratory tests, according to a report in the May issue of Archives of Surgery, one of the JAMA/Archives journals. "The use of laboratory tests has been rapidly increasing over the past few decades to the point where phlebotomy is a substantial proportion of hospital expenditure, and much of it is unwarranted," state the authors. As background, they ...

Objective evidence of skin infestation lacking in patients with diagnosis of delusional infestation

2011-05-17
Among patients with a diagnosis of delusional skin infestation, neither biopsies nor patient-provided specimens provided objective evidence of skin infestation, according to a report posted online today that will be published in the September issue of Archives of Dermatology, one of the JAMA/Archives journals. Delusional infestation is a condition in which patients steadfastly yet mistakenly believe that pathogens are infesting their skin. Sometimes, patients believe their skin is literally crawling with bugs, worms, or germs, which is also known as "delusions of parasitosis." ...

Propranolol associated with improvement in size and color of head and neck hemangiomas in children

2011-05-17
The beta-blocker propranolol appears to be associated with reducing the size and color of hemangiomas of the head and neck in a pediatric population, according to a report in the May issue of Archives of Otolaryngology–Head and Neck Surgery, one of the JAMA/Archives journals. According to background information in the article, hemangiomas are tumors that appear by the age of 2 months, affecting up to 10 percent of full-term white infants. These lesions can be benign, or can affect functions such as the ability to see or on occasion can be life-threatening if they occur ...

Nasal steroid spray may not help resolve dysfunction of the ear's eustachian tubes

2011-05-17
For patients with eustachian tube dysfunction (ETD), steroids administered by a nasal spray may be ineffective, according to a report in the May issue of Archives of Otolaryngology–Head and Neck Surgery, one of the JAMA/Archives journals. The eustachian tubes connect the middle ear, the upper part of the throat and the ends of the nasal passages. Eustachian tube dysfunction may contribute to fluid collection in the middle ear (otitis media with effusion, or OME) or negative middle ear pressure (NMEP). Presently there is no gold-standard single treatment for this condition, ...

Employees don't always share well with others, says new paper exposing 'knowledge hiding'

2011-05-17
Toronto - Why isn't knowledge transfer happening more often in companies spending money on it? Maybe it's because their staff don't always want to share. "We've had years of research in organizations about the benefits of knowledge-sharing but an important issue is the fact that people don't necessarily want to share their knowledge," says David Zweig, a professor of organizational behaviour and human resources management at the University of Toronto's Rotman School of Management and the University of Toronto at Scarborough. His paper, co-authored with Catherine ...

Surgical procedure appears to enhance smiles in children with facial paralysis

2011-05-17
Transferring a segment of muscle from the thigh appears to help restore the ability to smile in children with facial paralysis just as it does in adults, according to a report in the May issue of Archives of Facial Plastic Surgery, one of the JAMA/Archives journals. The article is part of a theme issue focusing on facial plastic surgery in the pediatric population. Facial paralysis often disrupts the ability to smile. In pediatric patients, this can be especially problematic, according to background information in the article. Surgery to repair the affected area may generate ...

Freedom in the swamp: Unearthing the secret history of the Great Dismal Swamp

Freedom in the swamp: Unearthing the secret history of the Great Dismal Swamp
2011-05-17
It's the year 1800. You're a slave in southeast Virginia. You manage to escape. Your freedom is only going to last as long as you can hide. Where do you go? Would you believe the Great Dismal Swamp? According to Dan Sayers, assistant professor of anthropology and an historical archaeologist at American University, that's exactly where you could have gone for immediate sanctuary. "There are interesting parallels. What was once more of a human refuge is now a natural refuge," said Sayers of the swamp, which officially became the Great Dismal Swamp National Wildlife ...

Abcc10 may be effective in extending the effectiveness of anticancer drugs

2011-05-17
PHILADELPHIA, PA (May 16, 2011)––Today's anticancer drugs often work wonders against malignancies, but sometimes tumors become resistant to the effects of such drugs, and treatment fails. Medical researchers would like to find ways of counteracting such resistance, but first they must understand why and how it happens. New findings by Fox Chase Cancer Center researchers identify one protein, Abcc10 (also known as Mrp7), as being intimately involved in resistance to certain drugs used to treat breast, ovarian, lung, and other cancers. The results suggest that blunting the ...

Duke-NUS researchers identify new cell that attacks dengue virus

2011-05-17
Durham, N.C., and Singapore – Mast cells, which can help the body respond to bacteria and pathogens, also apparently sound the alarm around viruses delivered by a mosquito bite, according to researchers at Duke-NUS Graduate Medical School in Singapore. "It appears the mast cells are activated and call immune system cells to the skin where they clear infection, which limits the spread of infection in the host," said lead researcher Ashley St. John, a Research Fellow with Duke-NUS in the Program in Emerging Infectious Diseases, and the Duke Department of Pathology in Durham, ...

LAST 30 PRESS RELEASES:

Singles differ in personality traits and life satisfaction compared to partnered people

President Biden signs bipartisan HEARTS Act into law

Advanced DNA storage: Cheng Zhang and Long Qian’s team introduce epi-bit method in Nature

New hope for male infertility: PKU researchers discover key mechanism in Klinefelter syndrome

Room-temperature non-volatile optical manipulation of polar order in a charge density wave

Coupled decline in ocean pH and carbonate saturation during the Palaeocene–Eocene Thermal Maximum

Unlocking the Future of Superconductors in non-van-der Waals 2D Polymers

Starlight to sight: Breakthrough in short-wave infrared detection

Land use changes and China’s carbon sequestration potential

PKU scientists reveals phenological divergence between plants and animals under climate change

Aerobic exercise and weight loss in adults

Persistent short sleep duration from pregnancy to 2 to 7 years after delivery and metabolic health

Kidney function decline after COVID-19 infection

Investigation uncovers poor quality of dental coverage under Medicare Advantage

Cooking sulfur-containing vegetables can promote the formation of trans-fatty acids

How do monkeys recognize snakes so fast?

Revolutionizing stent surgery for cardiovascular diseases with laser patterning technology

Fish-friendly dentistry: New method makes oral research non-lethal

Call for papers: 14th Asia-Pacific Conference on Transportation and the Environment (APTE 2025)

A novel disturbance rejection optimal guidance method for enhancing precision landing performance of reusable rockets

New scan method unveils lung function secrets

Searching for hidden medieval stories from the island of the Sagas

Breakthrough study reveals bumetanide treatment restores early social communication in fragile X syndrome mouse model

Neuroscience leader reveals oxytocin's crucial role beyond the 'love hormone' label

Twelve questions to ask your doctor for better brain health in the new year

Microelectronics Science Research Centers to lead charge on next-generation designs and prototypes

Study identifies genetic cause for yellow nail syndrome

New drug to prevent migraine may start working right away

Good news for people with MS: COVID-19 infection not tied to worsening symptoms

Department of Energy announces $179 million for Microelectronics Science Research Centers

[Press-News.org] Study links obesity to increased risk of developing postoperative infection following colon surgery