(Press-News.org) New Rochelle, NY, June 14, 2011—E. coli bacteria exposed to three common antibiotics were more likely to develop antibiotic resistance following low-level antibiotic exposure than after exposure to high concentrations that would kill the bacteria or inhibit their growth, according to a timely article in Microbial Drug Resistance, a peer-reviewed journal published by Mary Ann Liebert, Inc. The article is available free online at www.liebertpub.com/mdr
E. coli bacteria in food and water supplies have been responsible for disease outbreaks and deaths around the world in recent years. The current outbreak in Europe has sickened thousands of individuals and caused multiple deaths and life-threatening complications in hundreds of persons infected with a new strain of E. coli.
Bacterial resistance to commonly prescribed antibiotics is an enormous and growing problem, largely due to misuse of antibiotics to treat non-bacterial infections and environmental exposure of the bacteria to low levels of antibiotics used, for example, in agriculture. In the article "De Novo Acquisition of Resistance to Three Antibiotics by Escherichia coli," the authors studied the mechanisms by which E. coli acquire resistance to three common antibiotics: amoxicillin, tetracycline, and enrofloxacin. Depending on the antibiotic and the level of exposure, different mechanisms may come into play. The authors report that exposure to antibiotics at relatively low levels--below those needed to inhibit growth of the bacteria--are more likely to result in the development of antibiotic resistance. "Exposure to low levels of antibiotics therefore clearly poses most risk," a finding that "contradicts one of the main assumptions made questioning the threat of usage of antibiotics in food animals," conclude the authors.
INFORMATION:
Microbial Drug Resistance is an authoritative peer-reviewed international journal published quarterly in print and online that covers the growing threat and global spread of antibiotic resistant microbial pathogens and resistance genes. Led by Editor-in-Chief Alexander Tomasz, PhD, The Rockefeller University (New York, NY), the Journal covers topics that include the molecular biology of resistance mechanisms, virulence genes, and disease, as well as molecular epidemiology, drug design, infection control, and medical practice. Complete tables of content and a free sample issue may be viewed online at www.liebertpub.com/mdr
Mary Ann Liebert, Inc. (www.liebertpub.com) is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Foodborne Pathogens and Disease, Surgical Infections, and Vector-Borne and Zoonotic Diseases. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 60 journals, books, and newsmagazines is available at www.liebertpub.com
Mary Ann Liebert, Inc. 140 Huguenot St., New Rochelle, NY 10801-5215
Phone: (914) 740-2100 (800) M-LIEBERT Fax: (914) 740-2101
www.liebertpub.com
E. coli bacteria more likely to develop resistance after exposure to low levels of antibiotics, reports a study in Microbial Drug Resistance
2011-06-15
[Attachments] See images for this press release:
ELSE PRESS RELEASES FROM THIS DATE:
Noninvasive liver tests may predict hepatitis C patient survival
2011-06-15
Non-invasive tests for liver fibrosis, such as liver stiffness measurement or the FibroTest, can predict survival of patients with chronic hepatitis C, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.
"Liver stiffness measurement and/or the FibroTest could replace liver biopsy for the evaluation of hepatitis C, regardless of the stage of the disease," said Victor de Lédinghen, MD, PhD, of the Centre d' Investigation de la Fibrose Hépatique and lead author of this study. "Thus, these tools ...
Major flooding on the Mississippi River predicted to cause largest Gulf of Mexico dead zone ever recorded
2011-06-15
The Gulf of Mexico's hypoxic zone is predicted to be the largest ever recorded, due to extreme flooding of the Mississippi River this spring, according to an annual forecast by a team of NOAA-supported scientists from the Louisiana Universities Marine Consortium, Louisiana State University and the University of Michigan. The forecast is based on Mississippi River nutrient inputs compiled annually by the U.S. Geological Survey (USGS).
Scientists are predicting the area could measure between 8,500 and 9,421 square miles, or an area roughly the size of New Hampshire. If ...
New research provides clues on why hair turns gray
2011-06-15
A new study by researchers at NYU Langone Medical Center has shown that, for the first time, Wnt signaling, already known to control many biological processes, between hair follicles and melanocyte stem cells can dictate hair pigmentation. The study was published in the June 11, 2011 issue of the journal Cell.
The research was led by Mayumi Ito, PhD, assistant professor in the Ronald O. Pereleman Department of Dermatology at NYU Langone. "We have known for decades that hair follicle stem cells and pigment-producing melanocycte cells collaborate to produce colored hair, ...
Healing times for dental implants could be cut
2011-06-15
The technology used to replace lost teeth with titanium dental implants could be improved. By studying the surface structure of dental implants not only at micro level but also at nano level, researchers at the University of Gothenburg; Sweden, have come up with a method that could shorten the healing time for patients.
"Increasing the active surface at nano level and changing the conductivity of the implant allows us to affect the body's own biomechanics and speed up the healing of the implant," says Johanna Löberg at the University of Gothenburg's Department of Chemistry. ...
Physician-rating websites are biased, says paper at INFORMS Healthcare conference
2011-06-15
MONTREAL, June 14, 2011 – Patients posting their opinions about doctors on online ratings websites are much less likely to discuss physicians with low perceived quality and are more prone than offline populations to exaggerate their opinions, according to a paper being presented at a healthcare conference sponsored by the Institute for Operations Research and the Management Sciences (INFORMS®).
"Patients need high quality information about the most consequential service that they consume: healthcare," said Ritu Agarwal, professor of information systems and director ...
The surprising connection between 2 types of perception
2011-06-15
The brain is constantly changing as it perceives the outside world, processing and learning about everything it encounters. In a new study, which will be published in an upcoming issue of Psychological Science, a journal of the Association for Psychological Science, scientists find a surprising connection between two types of perception: If you're looking at a group of objects and getting a general sense of them, it's difficult for your brain to learn relationships between the objects.
It's not known how these two ways of perceiving are related, says Nicholas Turk-Browne, ...
New insights into the 'hidden' galaxies of the universe
2011-06-15
A unique example of some of the lowest surface brightness galaxies in the universe have been found by an international team of astronomers lead by the Niels Bohr Institute. The galaxy has lower amounts of heavier elements than other known galaxies of this type. The discovery means that small low surface brightness galaxies may have more in common with the first galaxies formed shortly after the Big Bang than previously thought. The results have been published in Monthly Notices of the Royal Astronomical Society.
As the name implies, the galaxies are faint and therefore ...
New research system uses social media and other tools to gather, analyze expert opinions
2011-06-15
Researchers have developed a new method of eliciting and analyzing opinions from a large group of experts and laypeople to aid complex decision-making, adapting online and social media technologies to lower the cost of such activities while expanding the types of people who can be queried.
The system, called ExpertLens, incorporates elements of such well-known approaches as the Delphi method, the Nominal Group Technique and crowdsourcing that are used to collect opinions about problems or to create forecasts. The online system and the associated methodology have performed ...
Fear boosts activation of young, immature brain cells
2011-06-15
Fear burns memories into our brain, and new research by University of California, Berkeley, neuroscientists explains how.
Scientists have long known that fear and other highly emotional experiences lead to incredibly strong memories. In a study appearing online today (Tuesday, June 14) in advance of publication in the journal Molecular Psychiatry, UC Berkeley's Daniela Kaufer and colleagues report a new way for emotions to affect memory: The brain's emotional center, the amygdala, induces the hippocampus, a relay hub for memory, to generate new neurons.
In a fearful ...
Parkinson's patients sing in tune with creative arts therapy
2011-06-15
CHICAGO – Twice a month a jam session takes place on the third floor of Northwestern Memorial's Prentice Women's Hospital. A diverse group of men and women, ranging in age and ethnicity, gather in a circle with instruments in hand and sing together. This is no ordinary jam band; all its members have Parkinson's disease. They are participating in Creative Arts for Parkinson's, a music and drama therapy program offered through Northwestern's Parkinson's Disease and Movement Disorders Center.
Creative Arts for Parkinson's is lead by specially trained music and drama therapists ...