PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Disclosure of financial conflicts of interest may worsen medical bias

2012-04-25
(Press-News.org) "Journals, professional associations, clinical guideline developers, and others need to worry not just that disclosure provides a band-aid to the real problem of the [conflict of interest] itself, but that any attempt to stem the trouble through disclosure policies may actually be worsening the problem," say the editors of PLoS Medicine writing in an editorial that discusses the response to a paper published in the Journal last month, which examined the financial conflicts of interest of members of the American Psychiatric Association (APA) responsible for updating the Diagnostic and Statistical Manual of Mental Disorders (DSM).

Media coverage about these findings raised concerns about the financial ties between many of the experts responsible for defining mental health conditions and treatments and the pharmaceutical companies that sell drugs for mental health. It is widely known that financial conflicts of interest impair objectivity and integrity in medicine.

But the editors ask: "are disclosure mandates simply a band-aid on an unrelenting problem of bias?"

The editors argue that although disclosure makes explicit and transparent details that are important to the interpretation, credibility, and value of the information presented, overemphasis and reliance on disclosure policies leaves the real problem of the conflict of interest unaddressed, and, according to studies in social science, may actually make the situation worse.

The editors say: "disclosure policies will never be the solution and are very likely exacerbating the problem of bias in medicine."

They continue: "Indeed, if disclosure worsens bias, then this is a game-changer for discussion and debate about managing conflicts of interest in medicine."

INFORMATION:

Funding: The authors are each paid a salary by the Public Library of Science, and they wrote this editorial during their salaried time.

Competing Interests: The authors' individual competing interests are at http://www.plosmedicine.org/static/editorsInterests.action. PLoS is funded partly through manuscript publication charges, but the PLoS Medicine Editors are paid a fixed salary (their salary is not linked to the number of papers published in the journal).

Citation: The PLoS Medicine Editors (2012) Does Conflict of Interest Disclosure Worsen Bias? PLoS Med 9(4): e1001210. doi:10.1371/journal.pmed.1001210

CONTACT:
Medicine_editors@plos.org
press@plos.org

A Comparison of DSM-IV and DSM-5 Panel Members' Financial Associations with Industry: A Pernicious Problem Persists by Lisa Cosgrove and Sheldon Krimsky

Funding: No specific funding was received for writing this article.

Competing Interests: The authors have declared that no competing interests exist.

Citation: Cosgrove L, Krimsky S (2012) A Comparison of DSM-IV and DSM-5 Panel Members' Financial Associations with Industry: A Pernicious Problem Persists. PLoS Med 9(3): e1001190. doi:10.1371/journal.pmed.1001190.

THE FREELY AVAILABLE PAPER: http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001190

END



ELSE PRESS RELEASES FROM THIS DATE:

Mayo Clinic identifies gene critical to development and spread of lung cancer

2012-04-25
JACKSONVILLE, Fla. — A single gene that promotes initial development of the most common form of lung cancer and its lethal metastases has been identified by researchers at Mayo Clinic in Florida. Their study suggests other forms of cancer may also be driven by this gene, matrix metalloproteinase-10 (MMP-10). The study, published in the journal PLoS ONE on April 24, shows that MMP-10 is a growth factor secreted and then used by cancer stem-like cells to keep themselves vital. These cells then drive lung cancer and its spread, and are notoriously immune to conventional ...

Guidelines for prostate screening widely ignored

Guidelines for prostate screening widely ignored
2012-04-25
New research confirms that the controversial decision by Warren Buffet – the 81-year-old CEO of Berkshire Hathaway – to undergo a blood test screening for prostate cancer despite his age is hardly unusual. Despite recommendations in 2008 from the United States Preventive Services Task Force against testing for prostate cancer in men aged 75 years or older, almost half of men in that age group continue to get screening tests. In 2005, before the recommendations were released, 43 percent of men age 75 and above elected to take the prostate-specific antigen (PSA) test. In ...

Connecting cilia: Cellular antennae help cells stick together

2012-04-25
Primary cilia are hair-like structures which protrude from almost all mammalian cells. They are thought to be sensory and involved in sampling the cell's environment. New research, published in BioMed Central's open access journal Cilia, launched today, shows that cilia on cells in the retina and liver are able to make stable connections with each other - indicating that cilia not only are able to sense their environment but are also involved in cell communication. Primary cilia are structurally and functionally very similar to eukaryotic flagella (motile tails used to ...

Discerning males remain faithful

Discerning males remain faithful
2012-04-25
Discerning males remain faithful ...if you are a spider. Sex for male orb web spiders (Argiope bruennichi) is a two shot affair since the act of mating destroys their genitalia. If they survive being eaten during their first encounter with a female, they have two choices – to mate again with the same female (monogynous) or try to find a new partner (bigynous). New research published in BioMed Central's open access journal Frontiers in Zoology shows that choice of mating behavior for A. bruennichi depends on the size and age of the first female they mate with. Monogamous ...

Plant perfumes woo beneficial bugs

2012-04-25
Scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) have discovered that maize crops emit chemical signals which attract growth-promoting microbes to live amongst their roots. This is the first chemical signal that has been shown to attract beneficial bacteria to the maize root environment. The study was led by Dr Andy Neal of Rothamsted Research in Hertfordshire and Dr Jurriaan Ton of the University of Sheffield's Department of Animal and Plant Sciences. By deepening our understanding of how cereals interact with microorganisms in ...

Early menopause linked to higher risk of osteoporosis, fracture and mortality

2012-04-25
Women who go through the menopause early are nearly twice as likely to suffer from osteoporosis in later life, suggests new research published today (25 April) in BJOG: An International Journal of Obstetrics and Gynaecology. The Swedish study looked at the long-term effects of early menopause on mortality, risk of fragility fracture and osteoporosis. In 1977, 390 white north European women aged 48 were recruited in the Malmo Perimenopausal Study, an observational study where women were followed from age 48 onwards. The women were divided into two categories; women ...

Global health priorities should shift to preventing risky behaviors in adolescence: UW professor

2012-04-25
As childhood and adolescent deaths from infectious diseases have declined worldwide, policymakers are shifting attention to preventing deaths from noncommunicable causes, such as drug and alcohol use, mental health problems, obesity, traffic crashes, violence and unsafe sex practices. "We now need to think of how to prevent these behavior problems and conditions early in life because they don't only cause problems in adolescence, they can launch health issues across life," said Richard Catalano, director of the University of Washington's Social Developmental Research ...

New Avalere study IDs 5 key practices that lead to successful hospital-to-home transitions

2012-04-25
Community health plans are improving how patients transition from hospital to home by breaking down silos of care, coordinating among providers, and directly engaging with patients, according to a new report entitled Transitions of Care from Hospital to Home. In the report, prepared by Avalere Health for the Alliance of Community Health Plans (ACHP), Avalere researchers examined ACHP community health plans and found five practices that the plans identified as facilitating the success of their care transitions programs: Using data to tailor care transition programs ...

Single scan could safely rule out pregnancy-related DVT

2012-04-25
Research: Diagnostic value of single complete compression ultrasonography in pregnant and postpartum women with suspected deep vein thrombosis: prospective study A single ultrasound scan (known as compression ultrasonography) may safely rule out a diagnosis of deep vein thrombosis (DVT) in women during pregnancy or in the first few weeks after giving birth (post-partum period), finds a study published on bmj.com today. During pregnancy the risk of DVT increases, but accurately diagnosing it is a challenge for doctors. Tests that are safe and reliable in non-pregnant ...

Many athletes with asthma may be using the wrong treatment

2012-04-25
Many athletes with asthma may not be using the best treatment for their condition and could be putting their long term health at risk, according to a roundup by journalist Sophie Arie published by the BMJ today. The article will feature on the BMJ's new Olympics portal, an online resource to keep doctors up to date with sports medicine content from across the BMJ Group. The portal will be open until the end of the Olympic and Para-Olympic games at www.bmj.com/olympics. Asthma is strikingly common in elite athletes and has gradually risen at almost every Olympics since ...

LAST 30 PRESS RELEASES:

Scientists can tell healthy and cancerous cells apart by how they move

Male athletes need higher BMI to define overweight or obesity

How thoughts influence what the eyes see

Unlocking the genetic basis of adaptive evolution: study reveals complex chromosomal rearrangements in a stick insect

Research Spotlight: Using artificial intelligence to reveal the neural dynamics of human conversation

Could opioid laws help curb domestic violence? New USF research says yes

NPS Applied Math Professor Wei Kang named 2025 SIAM Fellow

Scientists identify agent of transformation in protein blobs that morph from liquid to solid

Throwing a ‘spanner in the works’ of our cells’ machinery could help fight cancer, fatty liver disease… and hair loss

Research identifies key enzyme target to fight deadly brain cancers

New study unveils volcanic history and clues to ancient life on Mars

Monell Center study identifies GLP-1 therapies as a possible treatment for rare genetic disorder Bardet-Biedl syndrome

Scientists probe the mystery of Titan’s missing deltas

Q&A: What makes an ‘accidental dictator’ in the workplace?

Lehigh University water scientist Arup K. SenGupta honored with ASCE Freese Award and Lecture

Study highlights gaps in firearm suicide prevention among women

People with medical debt five times more likely to not receive mental health care treatment

Hydronidone for the treatment of liver fibrosis associated with chronic hepatitis B

Rise in claim denial rates for cancer-related advanced genetic testing

Legalizing youth-friendly cannabis edibles and extracts and adolescent cannabis use

Medical debt and forgone mental health care due to cost among adults

Colder temperatures increase gastroenteritis risk in Rohingya refugee camps

Acyclovir-induced nephrotoxicity: Protective potential of N-acetylcysteine

Inhibition of cyclooxygenase-2 upregulates the nuclear factor erythroid 2-related factor 2 signaling pathway to mitigate hepatocyte ferroptosis in chronic liver injury

AERA announces winners of the 2025 Palmer O. Johnson Memorial Award

Mapping minds: The neural fingerprint of team flow dynamics

Patients support AI as radiologist backup in screening mammography

AACR: MD Anderson’s John Weinstein elected Fellow of the AACR Academy

Existing drug has potential for immune paralysis

Soft brainstem implant delivers high-resolution hearing

[Press-News.org] Disclosure of financial conflicts of interest may worsen medical bias