PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Groundbreaking new model for predicting vaccine efficacy and safety

Groundbreaking new model for predicting vaccine efficacy and safety
2012-05-15
(Press-News.org) New Rochelle, NY, May 7, 2012—Vaccine testing and development is an extremely lengthy and complex process that costs billions of dollars every year. In an effort to dramatically improve the speed and success of vaccine research and development, researchers have created an innovative biomimetic model of the human immune system known as the MIMIC® system. An article in the inaugural issue of Disruptive Science and Technology, a peer-reviewed journal published by Mary Ann Liebert, Inc., describes this artificial human immune system which can facilitate faster, more effective vaccine development. For a copy of the article "In vitro Biomimetic Model of the Human Immune System for Predictive Vaccine Assessments," please contact journalmarketing1@liebertpub.com.

"Our goal is to increase the likelihood of success within the clinic– to make better drugs and vaccines and get them into the marketplace and to the patients faster," says William Warren, PhD, Head of the VaxDesign Campus, Sanofi Pasteur. "This in vitro human immune system enables us to measure vaccine efficacy earlier and more predictably."

The MIMIC® platform represents a truly disruptive technology for the study of vaccines and other biologics with immunomodulatory potential, as it provides a novel in vitro model for evaluating human immune responses against candidate drugs, adjuvants, and vaccines. It has shown game-changing advantages over conventional approaches to safety and efficacy testing.

INFORMATION:

About the Journal

Disruptive Science and Technology, a breakthrough, highly innovative, peer-reviewed journal spearheaded by Editor-in-Chief Alan J. Russell, PhD, Highmark Distinguished Professor, Carnegie Mellon University, cultivates, harnesses, and explores how existing paradigms can be changed to improve human health, well-being, and productivity. The Journal provides a multimedia platform and forum for ideas and opportunities, promotes breakthrough science and engineering, facilitates the innovator-market relationship, and accelerates the transition from bench to society. Bold, transparent, and resistant to limitations driven by protection of the science and engineering status quo, Disruptive Science and Technology provides the first destination for those seeking to publish game-changing results that have the capacity to alter the way we live. For complete journal details, please visit the Disruptive Science and Technology website at http://www.disruptivescience.com.

About the Publisher

Mary Ann Liebert, Inc. is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Tissue Engineering, Human Gene Therapy and HGT Methods, and Rejuvenation Research. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 70 journals, newsmagazines, and books is available on the Mary Ann Liebert, Inc. website at http://www.liebertpub.com.

Mary Ann Liebert, Inc.
140 Huguenot St., New Rochelle, NY 10801-5215
http://www.liebertpub.com
Phone: (914) 740-2100
(800) M-LIEBERT
Fax: (914) 740-2101

Mary Ann Liebert, Inc., publishers Contact: Sophie Mohin, smohin@liebertpub.com

Sanofi Pasteur Press Contact: Susan Watkins, Susan.Watkins@sanofipasteur.com

[Attachments] See images for this press release:
Groundbreaking new model for predicting vaccine efficacy and safety

ELSE PRESS RELEASES FROM THIS DATE:

Cutting-edge device controls acute inflammation

2012-05-15
New Rochelle, NY, May 7, 2012—The body's natural inflammatory response is an essential reaction to injury and infection. When acute inflammation escalates out of control, such as in sepsis, it causes nearly 10% of deaths in the U.S. and more than $17 billion in healthcare costs each year. A group of researchers have developed a groundbreaking biohybrid device that can control acute inflammation to prevent sepsis and other related life-threatening complications, as described in an article in the inaugural issue of Disruptive Science and Technology, a new peer-reviewed journal ...

May/June 2012 Annals of Family Medicine tip sheet

2012-05-15
Reinvigorating the 1967 Folsom Report's 'Communities of Solution' to Address Today's Fragmented U.S. Health Care System In the wake of federal efforts to reform the U.S. health care system, a group of rising family medicine leaders call for a reinvigoration of community-centered health systems, as originally outlined in the landmark 1967 Folsom Report. They contend the vision of the original Folsom commission could not be more pertinent to America's current pressing needs. The group revitalizes and modernizes the Folsom Report's blueprint, offering an updated series of ...

Embargoed news for Annals of Internal Medicine

2012-05-15
1. Self-management May Not be Safe or Suitable for COPD Trial of Comprehensive Care Management Program for COPD Cut Short Due to Excess Mortality Self-monitoring and management of some chronic diseases can improve patient outcomes. Hospitalizations for exacerbations of chronic obstructive pulmonary disease (COPD) are associated with decreases in quality of life, lung function, and life expectancy, so researchers hypothesized that a self-management program could benefit patients. The authors enrolled 960 COPD patients in 20 Veterans Affairs hospital-based outpatient ...

Laxative-free CT colonography may be as accurate as colonoscopy in detecting high-risk polyps

Laxative-free CT colonography may be as accurate as colonoscopy in detecting high-risk polyps
2012-05-15
A CT-scan-based form of virtual colonoscopy that does not require laxative preparation appears to be as effective as standard colonoscopy in identifying the intestinal polyps most likely to become cancerous. In the May 15 issue of Annals of Internal Medicine, a Massachusetts General Hospital (MGH)-based research team reports finding that the new technique, which uses computer-aided systems both to virtually cleanse and to analyze the images acquired, was able to identify more than 90 percent of the common polyps called adenomas that were 10 mm or larger. "While we know ...

Smoked cannabis can help relieve muscle tightness and pain in people with multiple sclerosis

2012-05-15
People with multiple sclerosis may find that smoked cannabis provides relief from muscle tightness — spasticity — and pain, although the benefits come with adverse cognitive effects, according to a new study published in CMAJ (Canadian Medical Association Journal). Many patients with multiple sclerosis suffer from spasticity, an uncomfortable and disabling condition in which the muscles become tight and difficult to control. While there are drugs to relieve spasticity, they can have adverse effects and do not always sufficiently improve the condition in some patients. Researchers ...

Back pain improves in first 6 weeks but lingering effects at 1 year

2012-05-15
For people receiving health care for acute and persistent low-back pain, symptoms will improve significantly in the first six weeks, but pain and disability may linger even after one year, states a large study published in CMAJ (Canadian Medical Association Journal). Low-back pain is a common condition that results in significant health care costs, disability and absenteeism in workplaces. However, there are differing views on how quickly and completely people recover from this condition. Researchers from Australia and Brazil examined data from 33 studies (11 166 participants) ...

Managing obesity in adults: Tips for primary care physicians

2012-05-15
Managing adult obesity is challenging for primary care physicians, but a new review published in CMAJ (Canadian Medical Association Journal) aims to provide an evidence-based approach to counselling patients to help them lose weight and maintain weight loss. "Even though evidence suggests that patients are considerably more likely to lose weight when they are advised to do so by their primary care physicians, most patients who are clinically obese do not receive weight-loss counselling in primary care," writes Dr. Gilles Plourde, Cliniques Médicales de Nutrition et d'Amaigrissement ...

Smoked cannabis reduces some symptoms of multiple sclerosis

2012-05-15
A clinical study of 30 adult patients with multiple sclerosis (MS) at the University of California, San Diego School of Medicine has shown that smoked cannabis may be an effective treatment for spasticity – a common and disabling symptom of this neurological disease. The placebo-controlled trial also resulted in reduced perception of pain, although participants also reported short-term, adverse cognitive effects and increased fatigue. The study will be published in the Canadian Medical Association Journal on May 14. Principal investigator Jody Corey-Bloom, MD, PhD, ...

Physical fitness may reduce hypertension risk in people with family history

2012-05-15
If your parents have a history of high blood pressure, you can significantly reduce your risk of developing the disease with moderate exercise and increased cardiovascular fitness, according to new research in the American Heart Association's journal Hypertension. In a study of more than 6,000 people, those who had a parent with high blood pressure but were highly fit had a 34 percent lower risk of developing high blood pressure themselves, compared to those with a low-fitness level who had the same parental history. "Understanding the roles that family history and ...

Sleepwalking more prevalent among US adults than previously suspected, Stanford researcher says

2012-05-15
STANFORD, Calif. — What goes bump in the night? In many U.S. households: people. That's according to new Stanford University School of Medicine research, which found that about 3.6 percent of U.S. adults - or upward of 8.4 million - are prone to sleepwalking. The work also showed an association between nocturnal wanderings and certain psychiatric disorders, such as depression and anxiety. The study, the researchers noted, "underscores the fact that sleepwalking is much more prevalent in adults than previously appreciated." Maurice Ohayon, MD, DSc, PhD, professor of ...

LAST 30 PRESS RELEASES:

The Lancet Obstetrics, Gynecology, & Women’s Health: Taking paracetamol during pregnancy does not increase risk of autism, ADHD or intellectual disabilities, confirms new gold-standard evidence review

Taking paracetamol during pregnancy does not increase risk of autism, ADHD or intellectual disabilities

Harm reduction vending machines in New York State expand access to overdose treatment and drug test strips, UB studies confirm

University of Phoenix releases white paper on Credit for Prior Learning as a catalyst for internal mobility and retention

Canada losing track of salmon health as climate and industrial threats mount

Molecular sieve-confined Pt-FeOx catalysts achieve highly efficient reversible hydrogen cycle of methylcyclohexane-toluene

Investment in farm productivity tools key to reducing greenhouse gas

New review highlights electrochemical pathways to recover uranium from wastewater and seawater

Hidden pollutants in shale gas development raise environmental concerns, new review finds

Discarded cigarette butts transformed into high performance energy storage materials

Researchers highlight role of alternative RNA splicing in schizophrenia

NTU Singapore scientists find new way to disarm antibiotic-resistant bacteria and restore healing in chronic wounds

Research suggests nationwide racial bias in media reporting on gun violence

Revealing the cell’s nanocourier at work

Health impacts of nursing home staffing

Public views about opioid overdose and people with opioid use disorder

Age-related changes in sperm DNA may play a role in autism risk

Ambitious model fails to explain near-death experiences, experts say

Multifaceted effects of inward foreign direct investment on new venture creation

Exploring mutations that spontaneously switch on a key brain cell receptor

Two-step genome editing enables the creation of full-length humanized mouse models

Pusan National University researchers develop light-activated tissue adhesive patch for rapid, watertight neurosurgical sealing

Study finds so-called super agers tend to have at least two key genetic advantages

Brain stimulation device cleared for ADHD in the US is overall safe but ineffective

Scientists discover natural ‘brake’ that could stop harmful inflammation

Tougher solid electrolyte advances long-sought lithium metal batteries

Experts provide policy roadmap to reduce dementia risk

New 3D imaging system could address limitations of MRI, CT and ultrasound

First-in-human drug trial lowers high blood fats

Decades of dredging are pushing the Dutch Western Scheldt Estuary beyond its ecological limits

[Press-News.org] Groundbreaking new model for predicting vaccine efficacy and safety