PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Chest physiotherapy not effective in infants hospitalized with acute bronchiolitis

2010-09-29
(Press-News.org) In research published this week in PLoS Medicine, Vincent Gajdos and colleagues report the results of a randomized trial conducted among hospitalized infants with bronchiolitis. The researchers enrolled nearly 500 children aged 15 days to 2 years who were admitted to seven French hospitals for a first episode of acute bronchiolitis. Their results show that a physiotherapy technique (increased exhalation and assisted cough) commonly used in France does not reduce time to recovery in this population. The researchers conclude "Our results did not support the recommendation that chest physiotherapy be routinely performed in hospitalized infants with acute bronchiolitis."

INFORMATION:

Funding:This work was supported by a grant from French Health Ministry (PHRC AOM 03/123) and by a grant from the Association des Reseaux Bronchiolites (ARB). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing Interests: All authors declare that (1) no financial support for the submitted work from anyone other than their employer; (2) no financial relationships with commercial entities that might have an interest in the submitted work in the previous 3 years; (3) no spouses, partners, or children with financial relationships that may be relevant to the submitted work; and (4) no non-financial interests that may be relevant to the submitted work.

Citation: Gajdos V, Katsahian S, Beydon N, Abadie V, de Pontual L, et al. (2010) Effectiveness of Chest Physiotherapy in Infants Hospitalized with Acute Bronchiolitis: A Multicenter, Randomized, Controlled Trial. PLoS Med 7(9): e1000345. doi:10.1371/journal.pmed.1000345

IN YOUR COVERAGE PLEASE USE THIS URL TO PROVIDE ACCESS TO THE FREELY AVAILABLE PAPER:

http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1000345

PRESS-ONLY PREVIEW OF THE ARTICLE: www.plos.org/press/plme-07-09-gajdos.pdf

CONTACT:

Vincent Gajdos

Hopital Antoine Beclere - APHP
Pediatric
157, rue de la porte de trivaux
Clamart, 92140
France
33 1 45 37 44 40
33 1 45 37 44 20 (fax)
vincent.gajdos@abc.aphp.fr

END



ELSE PRESS RELEASES FROM THIS DATE:

19-million-year-old genomic fossils of hepatitis B-like viruses in songbirds

2010-09-29
Biologists from The University of Texas at Arlington have uncovered virus fragments from the same family of the modern Hepatitis B virus locked inside the genomes of songbirds such as the modern-day zebra finch. The article, publishing next week in the online, open access journal PLoS Biology, marks the first time that endogenous hepadnaviruses have been found in any organism. An endogenous virus is one that deposits itself or fragments of itself into the chromosome of an organism, allowing it to be passed from generation-to-generation. Previously, most of these known "fossilized" ...

TGen/Mayo Clinic/Arizona Cancer Center study finds gene associated with aggressive skin cancer

2010-09-29
PHOENIX, Ariz. — Sept. 28, 2010 — The loss of a gene known as INPP5A could predict the onset, and track the progression, of an aggressive type of skin cancer, according to a study published today by the Arizona Cancer Center, Mayo Clinic and the Translational Genomics Research Institute (TGen). Targeting INPP5A could provide physicians with better ways to prevent and treat cutaneous squamous cell carcinoma, or SCC, a skin cancer that often spreads to other parts of the body, according to a scientific paper published today in the journal Cancer Prevention Research. "Loss ...

What next for the 2009 H1N1 influenza pandemic?

2010-09-29
WASHINGTON, DC – September 28, 2010 -- Now that the H1N1 influenza pandemic is officially over, what will happen to the virus? In a perspective article published today in the online open-access journal mBio®, scientists from the National Institutes of Health delve into history and explore the fates of other pandemic influenza viruses in order to speculate on the future of the most recent pandemic virus. "While human influenza viruses have often surprised us, available evidence leads to the hope that the current pandemic virus will continue to cause low or moderate mortality ...

Sodium plays key role in tissue regeneration

Sodium plays key role in tissue regeneration
2010-09-29
MEDFORD/SOMERVILLE, Mass. – Sodium gets a bad rap for contributing to hypertension and cardiovascular disease. Now biologists at Tufts University's School of Arts and Sciences have discovered that sodium also plays a key role in initiating a regenerative response after severe injury. The Tufts scientists have found a way to regenerate injured spinal cord and muscle by using small molecule drugs to trigger an influx of sodium ions into injured cells. The approach breaks new ground in the field of biomedicine because it requires no gene therapy; can be administered after ...

Pharma must be held more accountable to its human rights responsibilities

2010-09-29
In this week's PLoS Medicine, the Editors argue that drug companies should be held much more accountable for their human rights responsibilities to make medicines available and accessible to those in need. Despite decades of advocacy on the part of the access to medicines movement, and human rights guidelines developed in 2008 for pharmaceutical companies that make clear that their responsibilities go beyond stakeholder value to encompass human rights, there is inadequate accountability, say the Editors. "At the same time that the 825 billion dollar global pharmaceutical ...

NIH scientists consider fate of pandemic H1N1 flu virus

2010-09-29
Whither pandemic H1N1 virus? In a new commentary, scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, review the fates of previous pandemic influenza viruses in the years following a pandemic and speculate on possible future courses for the 2009 pandemic H1N1 (pH1N1) virus during the upcoming flu season and beyond. The authors estimate that at least 183 million Americans (about 59 percent of the total U.S. population) have some immunity to pH1N1 because they were exposed to related viruses or vaccines ...

Varying CRP levels in ethnic groups may affect statin eligibility, heart risk prediction

2010-09-29
Average C-reactive protein (CRP) values vary in diverse populations — possibly impacting how doctors estimate cardiovascular risk and determine statin treatment, according to a new study in Circulation: Cardiovascular Genetics, a journal of the American Heart Association. CRP is a marker of inflammation, and high levels of it in the blood have been associated with a higher risk for heart disease. But it's uncertain if the association is causal. Statins are a class of cholesterol-lowering drugs that reduce heart risk and CRP. Researchers aren't certain if CRP-lowering contributes ...

Genome inversion gives plant a new lifestyle

2010-09-29
DURHAM, N.C. – The yellow monkeyflower, an unassuming little plant that lives as both a perennial on the foggy coasts of the Pacific Northwest and a dry-land annual hundreds of miles inland, harbors a significant clue about evolution. Duke graduate student and native northern Californian David Lowry had become interested in how a single species could live such different lifestyles. He set out to find a gene or genes that would account for the monkeyflower (Mimulus guttatus) being a lush, moisture-loving, salt-tolerant perennial on the coast, but a shorter, faster-flowering, ...

Swine flu patients benefited from taking Tamiflu, says study

2010-09-29
Healthy people who caught swine flu during the 2009 pandemic may have been protected against developing radiographically (x-ray) confirmed pneumonia by taking the antiviral drug oseltamivir (Tamiflu), concludes a study of cases in China published on bmj.com today. The researchers also show that oseltamivir treatment was associated with shorter duration of fever and viral RNA shedding (the period when a virus is contagious), although they stress that their findings should be interpreted with caution. In 2009, pandemic influenza A (H1N1) virus spread rapidly, resulting ...

Unique Henry Ford case offers cautionary cotton swab tale

2010-09-29
DETROIT – The old saying, "never put anything smaller than your elbow in your ear," couldn't be truer for a patient who experienced vertigo and severe hearing loss after a cotton swab perforated her eardrum and damaged her inner ear. But what makes this patient's case unique is that otolaryngologists at Henry Ford Hospital in Detroit were not only able to alleviate her vertigo with surgery, but restore her hearing – an extremely rare occurrence. "This case is rare because the goal of surgery is not to recover hearing, but to improve vertigo," says case report lead ...

LAST 30 PRESS RELEASES:

Micronanoplastics found in artery-clogging plaque in the neck

TOS statement on oral GLP-1s

Pulmonary fibrosis has no cure. Could a cancer drug hold the answer?

Trial explores drug-free approach to treat ADHD symptoms in children exposed to alcohol before birth

New research points out a promising strategy for treating metastatic medulloblastoma

Light fields with extraordinary structure: plasmonic skyrmion bags

DNA origami guides new possibilities in the fight against pancreatic cancer

PREPSOIL launches assessment tool for soil living lab and lighthouse initiatives

Lebanon crisis driving parents to seek unregulated “shadow” education, study shows

The AGA Research Foundation awards $2.4 million in digestive health research funding

A repurposed anti-inflammatory drug may help treat alcohol use disorder and related pain

Obesity disrupts “reaction time” to starvation in mice

Listening to an avatar makes you more likely to gamble

Facial expressions of avatars promote risky decision-making

PREPSOIL Final Event: Facilitating the deployment of the Mission Soil across European regions

Politecnico di Milano: a study in Earth’s future on agrivoltaics reducing the competition between food and energy

Listeners use gestures to predict upcoming words

An AI tool grounded in evidence-based medicine outperformed other AI tools — and most doctors — on USMLE exams

Adolescents who sleep longer perform better at cognitive tasks

A ‘dopamine detox’ is too simplistic, new study finds

Alcohol use and abusive or neglectful behaviors among family caregivers of patients with dementia

Childhood exposure to air pollution, BMI trajectories and insulin resistance among young adults

JMIR Aging launches new section focused on advance care planning for older adults

Astronomers discover a planet that’s rapidly disintegrating, producing a comet-like tail

Study reveals gaps in flu treatment for high-risk adults

Oil cleanup agents do not impede natural biodegradation

AI algorithm can help identify high-risk heart patients to quickly diagnose, expedite, and improve care

Telemedicine had an impact on carbon emissions equivalent to reducing up to 130,000 car trips each month in 2023

Journalist David Zweig analyzes American schools, the virus, and a story of bad decisions

Endocrine Society names Tena-Sempere as next Editor-in-Chief of Endocrinology

[Press-News.org] Chest physiotherapy not effective in infants hospitalized with acute bronchiolitis