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Diet when young affects future food responses

2010-09-30
(Press-News.org) A high protein diet during development primes the body to react unhealthily to future food binges. A study on juvenile rats, published in BioMed Central's open access journal Nutrition and Metabolism, suggests that lasting changes result from altering the composition of the first solid food that is consumed throughout growth into early adulthood.

Raylene Reimer worked with a team of researchers from the University of Calgary, Canada, to carry out the weaning experiments in 18 litters of rats. Six litters were placed on each of three diets: high prebiotic fiber, high protein and normal control. They consumed these diets until they were 14 weeks old, when they were switched to a high fat, high sugar diet for a further six weeks. Reimer said, "After a weaning diet high in protein, the rats demonstrated an increase in body weight and fat mass in response to the high energy diet. They also showed higher energy intake than the fiber-diet rats".

This is the first study to investigate the long-term effects of high protein or fiber diets during development on the response to future food intake. Speaking about the results, Reimer said, "Overall, it appears that a long-term diet high in protein, when mismatched with a high energy challenge, has negative effects on body mass and hormones and genes involved in glucose and lipid metabolism. However, a fiber-enriched diet may provide some protection".

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Notes to Editors

1. Consumption of diets high in prebiotic fiber or protein during growth influences the response to a high fat and sucrose diet in adulthood in rats
Alannah D Maurer, Lindsay K Eller, Megan C Hallam, Kim Taylor and Raylene A Reimer
Nutrition & Metabolism (in press)

During embargo, article available here: http://www.nutritionandmetabolism.com/imedia/6308677163580472_article.pdf?random=803160

After the embargo, article available at the journal website: http://www.nutritionandmetabolism.com/

Please name the journal in any story you write. If you are writing for the web, please link to the article. All articles are available free of charge, according to BioMed Central's open access policy.

Article citation and URL available on request at press@biomedcentral.com on the day of publication.

2. Nutrition & Metabolism is an open access, peer-reviewed, online journal focused on the integration of nutrition, exercise physiology, clinical investigations, and molecular and cellular biochemistry of metabolism.

3. BioMed Central (http://www.biomedcentral.com/) is an STM (Science, Technology and Medicine) publisher which has pioneered the open access publishing model. All peer-reviewed research articles published by BioMed Central are made immediately and freely accessible online, and are licensed to allow redistribution and reuse. BioMed Central is part of Springer Science+Business Media, a leading global publisher in the STM sector.

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[Press-News.org] Diet when young affects future food responses