PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

CSIC recovers part of the genome of 2 hunter-gatherer individuals from 7,000 years ago

2012-06-29
(Press-News.org) A team of scientists, led by researcher Carles Lalueza-Fox from CSIC (Spanish National Research Council), has recovered - for the first time in history - part of the genome of two individuals living in the Mesolithic Period, 7000 years ago. Remains have been found at La Braña-Arintero site, located at Valdelugueros (León), Spain. The study results, published in the Current Biology magazine, indicate that current Iberian populations don't come from these groups genetically.

The Mesolithic Period, framed between the Paleolithic and Neolithic Periods, is characterized by the advent of agriculture, coming from the Middle East. Therefore, the genome found is the oldest from Prehistory, and exceeds Ötzi, the Iceman, in 1700 years.

Researchers have also recovered the complete mitochondrial DNA of one of these individuals, through which they could determine that European populations from Mesolithic Period were very uniform genetically. Carles Lauleza-Fox, from the Institute of Evolutionary Biology (CSIC-UPF), states: "These hunters-gatherers shared nomadic habits and had a common origin. Despite their geographical distance, individuals from the regions corresponding to the current England, Germany, Lithuania, Poland, and Spain, shared the same mitochondrial lineage".

The DNA data, which represent the 1.34% and the 0.5% of both individuals total genome, show that they are not directly connected to current populations of the Iberian Peninsula. Iberians from the Mesolithic Period were closer to current populations of northern Europe, who could have assimilated part of the genetic legacy of these hunters-gatherers.

La Braña-Arintero site was discovered in 2006 by chance. Juan Manuel Vidal Encinas, archeologist from the Regional Government of Castilla y León, who has also participated in the study, has excavated it at a later date. The cave, due to its location in a cold and mountainous area, is a suitable place for the good preservation of the DNA of these two individuals, found inside it.

The oldest remains from Prehistory

CSIC researcher emphasizes: "So far, we only had one genome of the European Prehistory, that of Ötzi [also known as the Iceman], from the Neolithic Period. His mummy, belonging to a man who lived 5300 years ago, was found in the Tyrolean Alps, on the border between Austria and Italy. La Braña-Arintero site offers a unique opportunity to obtain pre-Neolithic genomes".

According to Lalueza-Fox, this is only a first result since the intention of the team is to recover the complete DNA of these individuals, and to compare it with that of the modern humans. CSIC researcher discloses: "The arrival of the Neolithic Period brought about a replacement of populations, and could cause genetic changes in genes associated with new infectious diseases, and in metabolic genes linked to changes in diet. Therefore, all the information extracted from this genome will be absolutely important".



INFORMATION:



ELSE PRESS RELEASES FROM THIS DATE:

Dramatic change spotted on a faraway planet

2012-06-29
Astronomer Alain Lecavelier des Etangs (CNRS-UPMC, France) and his team used Hubble to observe the atmosphere of exoplanet HD 189733b [1] during two periods in early 2010 and late 2011, as it was silhouetted against its parent star [2]. While backlit in this way, the planet's atmosphere imprints its chemical signature on the starlight, allowing astronomers to decode what is happening on scales that are too tiny to image directly. The observations were carried out in order to confirm what the team had previously seen once before in a different planetary system: the evaporation ...

Rice researchers develop paintable battery

2012-06-29
HOUSTON – (June 28, 2012) – Researchers at Rice University have developed a lithium-ion battery that can be painted on virtually any surface. The rechargeable battery created in the lab of Rice materials scientist Pulickel Ajayan consists of spray-painted layers, each representing the components in a traditional battery. The research appears today in Nature's online, open-access journal Scientific Reports. "This means traditional packaging for batteries has given way to a much more flexible approach that allows all kinds of new design and integration possibilities ...

Discovery may lead to new tomato varieties with vintage flavor and quality

2012-06-29
A new discovery could make more tomatoes taste like heirlooms, reports an international research team headed by a University of California, Davis, plant scientist. The finding, which will be reported in the June 29 issue of the journal Science, has significant implications for the U.S. tomato industry, which annually harvests more than 15 million tons of the fruit for processing and fresh-market sales. "This information about the gene responsible for the trait in wild and traditional varieties provides a strategy to recapture quality characteristics that had been unknowingly ...

Caffeine boosts power for elderly muscles

2012-06-29
A new study to be presented at the Society for Experimental Biology meeting on 30th June has shown that caffeine boosts power in older muscles, suggesting the stimulant could aid elderly people to maintain their strength, reducing the incidence of falls and injuries. For adults in their prime, caffeine helps muscles to produce more force. But as we age, our muscles naturally change and become weaker. Sports scientists at Coventry University looked for the first time at whether these age-related changes in muscle would alter the effect of caffeine. They found that ...

A slow trek towards starvation: Scott's polar tragedy revisited

2012-06-29
On the centenary of Scott's ill-fated Terra Nova expedition to the South Pole, a study to be presented at the Society for Experimental Biology meeting on Sunday 1st July has shown that Scott's men starved to death because they were consuming far too few calories to fuel their daily exertion. The researchers, environmental physiologist Dr Lewis Halsey of the University of Roehampton and polar explorer and physician Dr Mike Stroud, examined the voyage in light of today's knowledge of nutrition and how our bodies respond to extreme exercise, cold, and high altitude. They ...

Insights into primate diversity: Lessons from the rhesus macaque

2012-06-29
New research published in BMC Genetics shows that the rhesus macaque has three times as much genetic variation than humans. However despite much of this extra variation being within genes, it does not affect protein function. Consequently damaging variations are at similar levels in macaques and humans - indicating a strong selection pressure to maintain gene function regardless of mutation rate or population size. Humans and rhesus macaques shared a common ancestor approximately 25 million years ago. Although there are now over seven billion humans on the planet only ...

What you eat can prevent arsenic overload

2012-06-29
Millions of people worldwide are exposed to arsenic from contaminated water, and we are all exposed to arsenic via the food we eat. New research published in BioMed Central's open access journal Nutrition Journal has demonstrated that people who ate more dietary vitamin B12 and animal protein had lower levels of arsenic (measured by deposition in toenails). Total dietary fat, animal fat, vegetable fat and saturated fat were also all associated with lower levels of arsenic, while omega 3 fatty acids, such as those found in fish oil, were associated with increased arsenic. Long ...

Gladstone scientists use stem cell technology to tackle Huntington's disease

2012-06-29
SAN FRANCISCO, CA—June 28, 2012—Scientists at the Gladstone Institutes and an international team of researchers have generated a human model of Huntington's disease—directly from the skin cells of patients with the disease. For years, scientists have studied Huntington's disease primarily in post-mortem brain tissue or laboratory animals modified to mimic the disease. Today, in Cell Stem Cell, the international team shows how they developed a human model of Huntington's disease, which causes a diverse range of neurological impairments. The new model should help scientists ...

Studying fish to learn about fat

2012-06-29
Baltimore, MD — In mammals, most lipids (such as fatty acids and cholesterol) are absorbed into the body via the small intestine. The complexity of the cells and fluids that inhabit this organ make it very difficult to study in a laboratory setting. New research from Carnegie's Steven Farber, James Walters and Jennifer Anderson reveals a technique that allows scientists to watch lipid metabolism in live zebrafish. This method enabled them to describe new aspects of lipid absorption that could have broad applications for human health. Their work is published in Chemistry ...

How sweet it is: Tomato researchers discover link between ripening, color and taste

2012-06-29
For many grocery shoppers, those perfect, red tomatoes from the store just can't match the flavor from the home garden. Now, researchers at Boyce Thompson Institute for Plant Research at Cornell University, USDA and the University of California at Davis have decoded a gene that contributes to the level of sugar, carbohydrates and carotenoids in tomatoes. (Science, June 29, 2012) Cuong Nguyen, a Cornell graduate student in plant breeding working at the Boyce Thompson Institute (BTI), along with colleagues at BTI, USDA, UC Davis, Universidad Politecénica de Valencia (Spain), ...

LAST 30 PRESS RELEASES:

Azacitidine–venetoclax combination outperforms standard care in acute myeloid leukemia patients eligible for intensive chemotherapy

Adding epcoritamab to standard second-line therapy improves follicular lymphoma outcomes

New findings support a chemo-free approach for treating Ph+ ALL

Non-covalent btki pirtobrutinib shows promise as frontline therapy for CLL/SLL

University of Cincinnati experts present research at annual hematology event

ASH 2025: Antibody therapy eradicates traces of multiple myeloma in preliminary trial

ASH 2025: AI uncovers how DNA architecture failures trigger blood cancer

ASH 2025: New study shows that patients can safely receive stem cell transplants from mismatched, unrelated donors

Protective regimen allows successful stem cell transplant even without close genetic match between donor and recipient

Continuous and fixed-duration treatments result in similar outcomes for CLL

Measurable residual disease shows strong potential as an early indicator of survival in patients with acute myeloid leukemia

Chemotherapy and radiation are comparable as pre-transplant conditioning for patients with b-acute lymphoblastic leukemia who have no measurable residual disease

Roughly one-third of families with children being treated for leukemia struggle to pay living expenses

Quality improvement project results in increased screening and treatment for iron deficiency in pregnancy

IV iron improves survival, increases hemoglobin in hospitalized patients with iron-deficiency anemia and an acute infection

Black patients with acute myeloid leukemia are younger at diagnosis and experience poorer survival outcomes than White patients

Emergency departments fall short on delivering timely treatment for sickle cell pain

Study shows no clear evidence of harm from hydroxyurea use during pregnancy

Long-term outlook is positive for most after hematopoietic cell transplant for sickle cell disease

Study offers real-world data on commercial implementation of gene therapies for sickle cell disease and beta thalassemia

Early results suggest exa-cel gene therapy works well in children

NTIDE: Disability employment holds steady after data hiatus

Social lives of viruses affect antiviral resistance

Dose of psilocybin, dash of rabies point to treatment for depression

Helping health care providers navigate social, political, and legal barriers to patient care

Barrow Neurological Institute, University of Calgary study urges “major change” to migraine treatment in Emergency Departments

Using smartphones to improve disaster search and rescue

Robust new photocatalyst paves the way for cleaner hydrogen peroxide production and greener chemical manufacturing

Ultrafast material captures toxic PFAS at record speed and capacity

Plant phenolic acids supercharge old antibiotics against multidrug resistant E. coli

[Press-News.org] CSIC recovers part of the genome of 2 hunter-gatherer individuals from 7,000 years ago