PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Diagnostic tool could help in the clinical diagnosis of cattle diseases in sub-Saharan Africa

2012-07-13
(Press-News.org) Diagnosis is key to the control and prevention of endemic livestock diseases in developing regions. New research has found the use of a low-cost diagnostic decision support tool could lead to the improvement in clinical practice by veterinary and animal health officers in sub-Saharan Africa.

An international team, led by Professor Mark Eisler, Chair in Global Farm Animal Health in the School of Veterinary Sciences at the University of Bristol, evaluated the effectiveness of a low-cost decision support tool as a diagnostic aid by observing whether its introduction to veterinary and animal health officers undertaking primary animal health care in Uganda could lead to changes in clinical practice. Their research is published today in PloS ONE.

Improved diagnosis is necessary for the effective management of endemic cattle diseases in sub-Saharan Africa. However, this is currently constrained by the limited availability of suitably trained professional staff and field-level diagnostic tests, and a general lack of knowledge about disease among livestock owners.

A number of parasites of cattle occur in the study area, including intestinal nematode worms, an animal form of sleeping sickness transmitted by the tsetse fly, a number of the tick-borne blood parasites, and liver and blood flukes that are transmitted by intermediate host snails living in swamps and marshland. The severe illnesses these parasites cause are difficult to distinguish, which is a problem for the African farmers dependant upon cattle for their livelihoods, as a different treatment is required for each.

Fifteen clinical participants undertaking primary animal health care in five districts of Uganda were recruited to take part in the study, including District Veterinary Officers, Veterinary Officers and Animal Health Officers.

They recorded their diagnoses for over 1,400 bovine clinical cases seen before and after the introduction of the low-cost diagnostic decision support tool implemented as a simple printed card that related each of eight key diseases to a number of clinical signs.

Professor Eisler said: "Reassuringly the diagnostic decision support tool covered the majority of diagnoses made before or after its introduction. Our most important finding was a significant increase in the number of clinical signs recorded, suggesting improvement in clinical examination as a key beneficial consequence of its use.

"It may also advise of a specific disease in a geographical area and be a useful epidemiological tool in poorly resourced areas."

Prior to the introduction of the tool the conditions most commonly diagnosed among 713 bovine clinical cases were trypanosomosis, theileriosis, anaplasmosis, and parasitic gastroenteritis (PGE).

Subsequently, in the next 747 bovine clinical cases examined the estimated proportional morbidity of fasciolosis doubled, while theileriosis and PGE were diagnosed significantly less frequently.

The average number of clinical signs increased from 3.5 to 4.9 per case, with 28 per cent of cases reporting six or more signs compared to just three per cent beforehand. Anaemia/pallor, weakness and a staring coat contributed most to this increase, approximately doubling in number and were recorded in over half of all cases, suggesting these key diagnostic indicators were under-observed prior to use of the tool.

The increase in the number of clinical signs recorded by participants showed the benefits of the diagnostic decision support tool and how its use in cattle can be seen in the same way as that of diagnostic "checklists" in human hospitals, improving efficiency and reducing missed clinical signs or mistaken diagnoses.

### END


ELSE PRESS RELEASES FROM THIS DATE:

The Clovis First Theory is put to rest at Paisley Caves

2012-07-13
Who were the first humans to enter the North American continent? Were they humans who founded what is known as the Clovis culture over 13,000 years ago? Or did other, totally unrelated peoples precede the Clovis immigrants? This issue has been intensely, if not bitterly debated for decades. The Clovis culture has been seen as the cradle of North American indigenous culture. Now new international research shows that people of another culture and technology were present concurrently or even previous to those of Clovis. Scientists have added a new and dramatic chapter to the ...

Winemaking goes high-tech at the University of British Columbia

2012-07-13
VANCOUVER, B.C. – July 11, 2012 – For centuries, people made wine by stomping grapes with their bare feet. But now, the art of winemaking is going high-tech at The University of British Columbia's Wine Research Centre. Have you ever gotten a headache or a rash from a single glass of wine? Has one glass of Merlot or Shiraz resulted in a painful hangover? If yes, you may be one of the 30 percent of people who are allergic to compounds that are in some of the world's most popular wines. A team of researchers at UBC's Wine Research Centre – which has received funding from ...

Protecting the hearts of those waiting for kidney and liver transplants

2012-07-13
As thousands of Americans await a life-saving kidney or liver transplant, medical teams are paying close attention to another organ: their hearts. This month the American Heart Association attempts to bring harmony to the varied cardiac evaluation policies created at U.S. hospitals that assess a patient's overall health before transplant surgery. Approximately 85,000 people are on the waiting list for a kidney transplant and 16,000 are waiting for a liver. It's not unusual for these transplant candidates to be well over age 50 and at increased risk for heart disease. The ...

Peering into the heart of a supernova

2012-07-13
PASADENA, Calif.—Each century, about two massive stars in our own galaxy explode, producing magnificent supernovae. These stellar explosions send fundamental, uncharged particles called neutrinos streaming our way and generate ripples called gravitational waves in the fabric of space-time. Scientists are waiting for the neutrinos and gravitational waves from about 1000 supernovae that have already exploded at distant locations in the Milky Way to reach us. Here on Earth, large, sensitive neutrino and gravitational-wave detectors have the ability to detect these respective ...

Our coral reefs: In trouble - but tougher than we thought

2012-07-13
Coral reefs in the Indo-Pacific region, including the Great Barrier Reef, recover faster from major stresses than their Caribbean counterparts, leading marine scientists said today. Dr George Roff and Professor Peter Mumby from the ARC Centre of Excellence for Coral Reef Studies and The University of Queensland told the 12th International Coral Reef Symposium in Cairns that coral reefs in the Indo-Pacific Ocean are naturally tougher than the Caribbean reefs. "The main reason that Indo-Pacific reefs are more resilient is they have less seaweed than the Caribbean Sea," ...

Collagenase for Dupuytren's contracture: Added benefit not proven

2012-07-13
Collagenase extracted from Clostridium histolyticum (trade name: Xiapex®) was approved in the beginning of 2011 for the treatment of people with Dupuytren's contracture. In an early benefit assessment pursuant to the "Act on the Reform of the Market for Medicinal Products" (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether collagenase offers an added benefit in comparison with conventional regimens. However, such an added benefit cannot be inferred from the dossier, as the drug manufacturer presented either no data or unsuitable ...

Multiple sclerosis: New marker could improve diagnosis

2012-07-13
For the first time, scientists in Germany's multiple sclerosis competence network have been able to identify an antibody that bonds with the potassium channel KIR4.1. "We found this autoantibody in almost half of the MS patients in our study," explains Bernhard Hemmer, Professor of Neurology at the Klinikum rechts der Isar hospital at Technische Universitaet Muenchen (TUM). The biomarker was not present in healthy patients. The findings could therefore indicate that KIR4.1 is one of the targets of the autoimmune response in MS. Humans and animals without the KIR4.1 channel ...

Controlling your computer with your eyes

2012-07-13
Millions of people suffering from Multiple Sclerosis, Parkinson's, muscular dystrophy, spinal cord injuries or amputees could soon interact with their computers and surroundings using just their eyes, thanks to a new device that costs less than £40. Composed from off-the-shelf materials, the new device can work out exactly where a person is looking by tracking their eye movements, allowing them to control a cursor on a screen just like a normal computer mouse. The technology comprises an eye-tracking device and "smart" software that have been presented today, Friday ...

Current and former smokers at risk for recurrent hepatitis post-liver transplantation

2012-07-13
Transplant recipients who smoke or have smoked increase their risk of viral hepatitis reinfection following liver transplantation according to new research available in the July issue of Liver Transplantation, a journal published by Wiley on behalf of American Association for the Study of Liver Diseases. Findings suggest that tobacco in cigarettes may adversely affect immune system response in patients transplanted for viral hepatitis. According to the Centers for Disease Control and Prevention (CDC), tobacco use causes more than five million deaths per year worldwide, ...

Fossil egg discovered in Lleida (Spain) links dinosaurs to modern birds

2012-07-13
Before her death in December 2010, Nieves López Martínez, palaeontologist of the Complutense University of Madrid, was working on the research of dinosaur eggs with a very peculiar characteristic: an ovoid, asymmetrical shape. Together with Enric Vicens, palaeontologist of the Universitat Autònoma de Barcelona, the two scientists conducted an exhaustive analysis of their discovery, recently published in the journal Palaeontology. The new type of dinosaur egg has been given the scientific name of Sankofa pyrenaica. The eggs were discovered in the Montsec area of Lleida, ...

LAST 30 PRESS RELEASES:

Making lighter work of calculating fluid and heat flow

Normalizing blood sugar can halve heart attack risk

Lowering blood sugar cuts heart attack risk in people with prediabetes

Study links genetic variants to risk of blinding eye disease in premature infants

Non-opioid ‘pain sponge’ therapy halts cartilage degeneration and relieves chronic pain

AI can pick up cultural values by mimicking how kids learn

China’s ecological redlines offer fast track to 30 x 30 global conservation goal

Invisible indoor threats: emerging household contaminants and their growing risks to human health

Adding antibody treatment to chemo boosts outcomes for children with rare cancer

Germline pathogenic variants among women without a history of breast cancer

Tanning beds triple melanoma risk, potentially causing broad DNA damage

Unique bond identified as key to viral infection speed

Indoor tanning makes youthful skin much older on a genetic level

Mouse model sheds new light on the causes and potential solutions to human GI problems linked to muscular dystrophy

The Journal of Nuclear Medicine ahead-of-print tip sheet: December 12, 2025

Smarter tools for peering into the microscopic world

Applications open for funding to conduct research in the Kinsey Institute archives

Global measure underestimates the severity of food insecurity

Child survivors of critical illness are missing out on timely follow up care

Risk-based vs annual breast cancer screening / the WISDOM randomized clinical trial

University of Toronto launches Electric Vehicle Innovation Ontario to accelerate advanced EV technologies and build Canada’s innovation advantage

Early relapse predicts poor outcomes in aggressive blood cancer

American College of Lifestyle Medicine applauds two CMS models aligned with lifestyle medicine practice and reimbursement

Clinical trial finds cannabis use not a barrier to quitting nicotine vaping

Supplemental nutrition assistance program policies and food insecurity

Switching immune cells to “night mode” could limit damage after a heart attack, study suggests

URI-based Global RIghts Project report spotlights continued troubling trends in worldwide inhumane treatment

Neutrophils are less aggressive at night, explaining why nighttime heart attacks cause less damage than daytime events

Menopausal hormone therapy may not pose breast cancer risk for women with BRCA mutations

Mobile health tool may improve quality of life for adolescent and young adult breast cancer survivors

[Press-News.org] Diagnostic tool could help in the clinical diagnosis of cattle diseases in sub-Saharan Africa