PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Researchers develop new method for identifying lung nodules

Identification system for community settings

2012-07-17
(Press-News.org) DENVER – Pulmonary nodules are common, but few studies of lung nodule identification and clinical evaluation have been performed in community settings. Researchers from Kaiser Permanente Southern California identified 7,112 patients who had one or more nodules by using existing information within the electronic medical record.

Their study presented in the August 2012 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology, showed how researchers developed and implemented a new method for identifying lung nodules in community-based settings.

The researchers used a combination of ICD-9 codes, CPT codes and an algorithm for natural language processing (NLP) to classify the nodules. This automated method had a 96 percent sensitivity and 86 percent specificity compared to clinician review.

The authors suggest that the automated process, "could be used to study the incidence and prevalence of lung nodules in large popula¬tions, with the caveat that approximately 13 percent of cases identi¬fied by the automated method would not meet our definition of one or more nodules (e.g., be false-positives)."

Since this study favored sensitivity over specificity, the authors advise that the method "could be used as a sensitive first step to be followed by more specific review of radiology transcripts or actual imaging studies."

As screening programs for lung cancer have proven to be beneficial in specific high-risk populations, this study also provides useful information for the study of screen-detected nodules.

INFORMATION:

The lead author of this work is Kim Danforth, ScD, MPH, Kaiser Permanente Southern California, Department of Research & Evaluation. The senior author is Michael Gould, MD, MS, Kaiser Permanente Southern California, Department of Research & Evaluation.

About the IASLC: The International Association for the Study of Lung Cancer (IASLC) is the only global organization dedicated to the study of lung cancer. Founded in 1974, the association's membership includes more than 3,500 lung cancer specialists in 80 countries. To learn more about IASLC please visit www.iaslc.org.

END



ELSE PRESS RELEASES FROM THIS DATE:

Managers realize highest professional vitality in 50s

2012-07-17
Managers demonstrate their highest levels of professional vitality in their 50s, reveals a new study conducted at the University of Haifa, Israel, which examined the functionality of high-tech, engineering, and infrastructure executives. "The advantages and disadvantages of taking on mature employees have been widely debated over the past few years. This new study now shows that in terms of vitality, advancing age plays a significant role," note Dr. Shmuel Grimland, Prof. Yehuda Baruch, and Prof. Eran Vigoda-Gadot, who conducted the study. A manager's professional vitality ...

Copper's previously unknown exit strategy

2012-07-17
Scientists have long known that the body rids itself of excess copper and various other minerals by collecting them in the liver and excreting them through the liver's bile. However, a new study led by Johns Hopkins researchers and published June 22 in PLoS ONE suggests that when this route is impaired there's another exit route just for copper: A molecule sequesters only that mineral and routes it from the body through urine. The researchers, led by Svetlana Lutsenko, Ph.D., a professor of physiology at the Johns Hopkins University School of Medicine, found this additional ...

Annals of Internal Medicine tip sheet for July 17, 2012 issue

2012-07-17
1. Trans Fat Restrictions Result in Healthier Fast Food Meals for NYC Residents Reduction in Trans Fat Consumption Can Reduce Cardiovascular Disease Risk (Sound bites and b-roll footage available. See bottom of page for feed dates, times, and coordinates) Trans fat, such as partially hydrogenated oil, is a mostly processed form of fat that significantly increases risk for coronary heart disease. Just 40 calories of trans fat a day can increase risk for heart disease by up to 23 percent. In 2006 New York City issued unprecedented restrictions on the use of trans fats ...

Amnestic mild cognitive impairment doubles risk of death

2012-07-17
July 16, 2012 – (BRONX, NY) – Researchers at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center have found that people with a form of mild cognitive impairment (MCI), a risk factor for developing Alzheimer's disease, have twice the risk of dying compared with cognitively normal people. Those with dementia have three times the risk. The findings are being presented at the Alzheimer's Association International Conference in Vancouver this week. Amnestic MCI is a condition in which people have memory problems more severe than normal for ...

New research shows that coastal populations are healthier than those inland

2012-07-17
A new study from the European Centre for Environment & Human Health, Peninsula College of Medicine and Dentistry, University of Exeter, has revealed that people living near the coast tend to have better health than those living inland. Researchers from the Centre used data from the UK's census to examine how health varied across the country, finding that people were more likely to have good health the closer they live to the sea. The analysis also showed that the link between living near the coast and good health was strongest in the most economically deprived communities. The ...

Have thieving rodents saved tropical trees?

2012-07-17
VIDEO: This video shows relative movement paths of 224 radio-tagged palm seeds handled by rodents on Barro Colorado Island, Panama. Colored dots mark locations of 129 seeds that were found eaten... Click here for more information. Big seeds produced by many tropical trees were probably once ingested and then defecated whole by huge mammals called gomphotheres that dispersed the seeds over large distances. But gomphotheres were probably hunted to extinction more than 10,000 ...

JCI early table of contents for July 16, 2012

2012-07-17
ONCOLOGY A new target in acute myeloid leukemia | Back to top Acute myeloid leukemia, a common leukemia in adults, is characterized by aberrant proliferation of cancerous bone marrow cells. Activating mutations in a protein receptor known as FLT3 receptor are among the most prevalent mutations observed in acute myeloid leukemias. FLT3 mutants are thought to activate several signaling pathways that contribute to cancer development. Dr. Daniel Tenen and colleagues from Harvard University in Boston discovered a new pathway activated by FLT3 mutation. Their results show ...

A new target in acute myeloid leukemia

2012-07-17
Acute myeloid leukemia, a common leukemia in adults, is characterized by aberrant proliferation of cancerous bone marrow cells. Activating mutations in a protein receptor known as FLT3 receptor are among the most prevalent mutations observed in acute myeloid leukemias. FLT3 mutants are thought to activate several signaling pathways that contribute to cancer development. Dr. Daniel Tenen and colleagues from Harvard University in Boston discovered a new pathway activated by FLT3 mutation. Their results show that cyclin dependent kinase 1 (CDK1), a critical regulator of cell ...

Updated AHA/ACCF guidelines for unstable angina include newest blood-thinning drug

2012-07-17
Ticagrelor, a blood-thinning drug approved by the FDA in 2011, should be considered along with older blood thinners clopidogrel and prasugrel for treating patients who are experiencing chest pain or some heart attacks, according to joint updated guidelines issued by the American Heart Association (AHA) Task Force on Practice Guidelines and the American College of Cardiology (ACCF) Foundation. The "focused update" on unstable angina (chest pain) or a specific kind of heart attack known as non-ST-elevation myocardial infarction (NSTEMI) is published in Circulation: Journal ...

Frail, older adults with high blood pressure may have lower risk of mortality

2012-07-17
CORVALLIS, Ore. – A new study suggests that higher blood pressure is associated with lower mortality in extremely frail, elderly adults. The study, published today in the Journal of the American Medical Association's (JAMA) Archives of Internal Medicine, looked at a nationally representative group of 2,340 adults ages 65 and older. The researchers found that lower blood pressure protected healthier, robust older adults but the same may not be true for their more frail counterparts. Lead author Michelle Odden, a public health epidemiologist at Oregon State University, ...

LAST 30 PRESS RELEASES:

Ideal nitrogen fertilizer rates in Corn Belt have been climbing for decades, Iowa State study shows

Survey suggests people with disabilities may feel disrespected by health care providers

U-Michigan, UC Riverside launch alliance to promote hydrogen-fueled internal combustion engines

New insights into network power response: Unveiling multi-timescale characteristics

Simple algorithm helps improve treatment, reduce disparities in MS

Despite high employment rates, Black immigrants in the United States more likely to be uninsured, USC study shows

Research supports move toward better tailoring stroke rehabilitation

Imagining future events changes brain to improve healthy decision-making, new study indicates

Turning plastic waste into valuable resources: A new photocatalytic approach

Sea otters help kelp forests recover — but how fast depends on where they are

Study links intense energy bursts to ventilator-induced lung injury

Uncovering the protein complex critical to male fertility

Scientists discover how a naturally occurring mechanism hampers fertility

Integrated framework for ecological security: A case study of the Daqing river basin

New design paradigm boosts reconfigurable intelligent surface efficiency

Long-term cocaine use may increase impulsivity

How London’s Ultra Low Emission Zone is changing the school run

Breakthrough CRISPR-based test offers faster, more accurate diagnosis for fungal pneumonia

3D-printed knee implants improves quality and reliability

UC San Diego innovators to spotlight transformative science at SXSW 2025

Burning question: How to save an old-growth forest in Tahoe

SwRI, U-Michigan engineers create more effective burner to reduce methane emissions

Dental implants still functional after forty years

A hot droplet can bounce across a cool pan, too

Synthetic microbiome therapy suppresses bacterial infection without antibiotics

New mouse study: How to trick the body's metabolism

Rates of population-level child sexual abuse after a community-wide preventive intervention

Rural-urban disparities in cervical cancer incidence and mortality among US women

Tele-buprenorphine initiations for opioid use disorder without in-person relationships

Researchers reveal key mechanism behind bacterial cancer therapy

[Press-News.org] Researchers develop new method for identifying lung nodules
Identification system for community settings