PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Heart separation device improves 3 year outcomes in heart failure patients

2012-08-27
(Press-News.org) Munich, Germany – A novel non-invasive device which separates healthy and damaged heart muscle and restores ventricle function improves 3 year outcomes in patients with ischemic heart failure, according to research presented at the ESC Congress 2012. The findings were presented by Professor William T. Abraham at an ESC press conference on 25 August and by Dr Marco Costa at an ESC Congress scientific session on 27 August.

Heart failure is a common, debilitating, and potentially deadly condition in which the heart is unable to supply sufficient blood flow to meet the needs of the body. Symptoms of heart failure negatively impact quality of life and include shortness of breath, persistent coughing or wheezing, buildup of excess fluid in body tissues (edema), fatigue, lack of appetite or nausea, impaired thinking, and increased heart rate. More than 20 million people around the world are affected.

Many heart attack survivors experience enlargement of the heart, causing a decrease in cardiac output that results in heart failure symptoms such as fatigue and shortness of breath. The healthy portion of the heart not affected by the heart attack has to compensate for the loss in output and becomes overloaded over time. Current treatment options for patients whose hearts have enlarged are limited.

The Parachute Ventricular Partitioning Device is the first minimally invasive treatment for patients with heart failure caused by damage to the heart muscle following a heart attack. The Parachute device is implanted in the left ventricle through a small catheter inserted in the femoral artery.

"The device creates a barrier between the non-functioning, damaged segment of heart muscle and the healthy, functional segment of heart muscle," said Dr Costa. "This decreases the overall volume of the left ventricle chamber and restores its optimal geometry and function. The procedure is performed in the catheterization laboratory under conscious sedation."

Two-year clinical data presented at the EuroPCR conference earlier this year demonstrated improved overall cardiac function and quality of life for patients treated with the Parachute device.

The current study included 31patients treated in the US and Europe with the Parachute system. The New York Heart Association (NYHA) Functional Classification of 1 (mildest) to 4 (most severe) was used to define the severity of heart failure at 1, 2 and 3 years after treatment.

The average NYHA class at baseline was 2.6. This improved to 1.6 (p END


ELSE PRESS RELEASES FROM THIS DATE:

Promising new drug target discovered for treatment and prevention of heart failure

2012-08-27
Munich, Germany – A promising new drug target for the treatment and prevention of heart failure has been discovered by researchers at Mount Sinai School of Medicine in New York, NY, US. The study was presented at the ESC Congress 2012 by principal investigator Professor Roger J. Hajjar, MD. According to the US Centers for Disease Control and Prevention, about 5.8 million Americans suffer from heart failure and 670,000 new cases are diagnosed each year. One in five people with heart failure die within one year of diagnosis. Heart failure is most often treated with aggressive ...

Novel anti-platelet therapy reduces risk of cardiac events in patients with history of heart attack

2012-08-27
According to new research from Brigham and Women's Hospital (BWH), adding vorapaxar, an investigational platelet blocker, to standard antiplatelet therapy significantly reduces the long-term risk of recurrent cardiovascular events beyond one year in patients with a history of a prior heart attack. Researchers also identify a low-bleeding risk group among whom the clinical benefit of vorapaxar was particularly favorable. This research is presented at the European Society of Cardiology Congress 2012 and published simultaneously in the Lancet. For more than a million Americans ...

The PURE study

2012-08-27
Munich, Germany – Healthy foods such as fruits and vegetables, proteins and non-saturated fats are consumed more often by the wealthy while poorer people consume more carbohydrates, concludes a new study involving people from 17 countries. Results from the Prospective Urban Rural Epidemiology (PURE) study were reported here today by Professor Salim Yusuf of the Population Health Research Institute, McMaster University and Hamilton Health Sciences, in Hamilton, Canada and principal investigator of the study. The study, involving 154,000 individuals from 628 communities, ...

The DeFACTO study

2012-08-27
Munich, Germany – Data presented today from the prospective Determination of Fractional Flow Reserve by Anatomic Computed Tomographic Angiography (DeFACTO) study show that, when compared to standard coronary angiography (CT), the non-invasive assessment of fractional flow reserve by computed tomography (FFRct) provides a more accurate determination of which lesions require invasive evaluation.(1) The results of the study were presented by Dr James K. Min, director of Cardiac Imaging Research and co-director of Cardiac Imaging at the Department of Medicine, Imaging and ...

Median follow-up results from the ALTITUDE study, stopped prematurely in December 2011

2012-08-27
Munich, Germany – Preliminary results from the Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Endpoints (ALTITUDE) do not support administration of aliskiren on top of standard therapy with renin-angiotensin-aldosterone system (RAAS) blockade in type 2 diabetics at high risk of cardiovascular and renal events, according to Professor Hans-Henrik Parving from Rigshospitalet, University of Copenhagen, Denmark. Presenting results from the study today, he said the treatment "may even be harmful". The ALTITUDE trial was stopped prematurely in December 2011 on recommendation ...

The TRILOGY ACS study

2012-08-27
Munich, Germany – The first trial to study the effect of platelet inhibition in patients with acute coronary syndromes managed medically without revascularisation has found no significant difference between prasugrel and clopidogrel in the prevention of death, myocardial infarction or stroke. The findings, from the phase III Targeted Platelet Inhibition to Clarify the Optimal Strategy to Medically Manage Acute Coronary Syndromes (TRILOGY ACS) study, were presented today at a Hot Line session of ESC Congress 2012 in Munich. TRILOGY ACS was double-blind, randomised trial ...

The PARAMOUNT study

2012-08-27
Munich, Germany – The novel angiotensin receptor neprilysin inhibitor, LCZ696, demonstrated beneficial effects in heart failure patients with preserved ejection fraction (HFpEF), according to results of the PARAMOUNT (Prospective compArison of ARNI with ARB on Management Of heart failUre with preserved ejectioN fracTion) trial. Approximately half of all heart failure patients have normal or nearly normal ejection fraction, a measure of their strength of cardiac contraction. However, while many studies have shown a benefit of pharmacological therapies in heart failure ...

The Aldo-DHF study

2012-08-27
Munich, Germany – Mineralocorticoid receptor antagonists should be considered as a treatment option in hypertensive patients with diastolic heart failure, said Professor Burkert Pieske presenting results today of the Aldosterone Receptor Blockade in Diastolic Heart Failure (Aldo-DHF) study at ESC Congress 2012. Behind his conclusion lay results showing that mineralocorticoid receptor blockade with spironolactone improves cardiac function and structure, reduces neuroendocrine activation, and effectively reduces blood pressure in a patient population with symptomatic predominantly ...

Obesity triggers AF in fertile women

2012-08-27
Munich, Germany – Obesity triggers atrial fibrillation in fertile women, according to research presented today at the ESC Congress 2012 by Dr Deniz Karasoy from Denmark. Atrial fibrillation and obesity are among the largest public health related challenges in the western world today. Atrial fibrillation is the commonest heart rhythm disorder and is associated with increased mortality and morbidity. Previous studies have demonstrated that obesity increases the risk of new-onset atrial fibrillation in individuals with known risk factors for developing atrial fibrillation ...

Female gender increases stroke risk in AF patients aged over 75 years by 20%

2012-08-27
Munich, Germany – Female gender increases the risk of stroke in patients with atrial fibrillation (AF) aged >75 years by 20%, according to a study presented today at the ESC Congress 2012. The findings were presented by Anders Mikkelsen, from Denmark. The results suggest that female gender should not be included as an independent stroke/thromboembolism (TE) risk factor in guidelines or risk stratification schemes used in treatment of patients with atrial fibrillation. The increased risk of stroke and TE in patients with atrial fibrillation depends on additional risk ...

LAST 30 PRESS RELEASES:

Robotic space rovers keep getting stuck. UW engineers have figured out why

New research shows how immigration status can become a death sentence during public health crisis

University of Toronto Engineering researchers develop safer alternative non-stick coating

Good vibrations: Scientists use imaging technology to visualize heat

More ecological diversity means better nutritional resources in Fiji’s agroforests

New global study shows freshwater is disappearing at alarming rates

Scientists create an artificial cell capable of navigating its environment using chemistry alone

A little salt is good for battery health

Deep-sea fish confirmed as a significant source of ocean carbonate

How to keep kids with eating disorders home after hospital stay? Therapy

Sex differences affect efficacy of opioid overdose treatment

Aligning AI with Human Values and Well-Being

Engineering the next generation of experimental physics

The scuba diving industry is funding marine ecosystem conservation and employing locals

BATMAN brings TCR therapy out of the shadows

Surrogates more likely to be diagnosed with mental illness, study finds

Columbia Engineering researchers turn dairy byproduct into tissue repair gel

Global estimates of lives and life-years saved by COVID-19 vaccination during 2020-2024

Potential trade-offs of proposed cuts to the NIH

New research simulates cancer cell behavior

COVID, over 2.5 million deaths prevented worldwide thanks to vaccines. One life saved for every 5,400 doses administered

Scuba diving generates up to $20 billion annually

Scientists advance efforts to create ‘virtual cell lab’ as testing ground for future research with live cells

How DNA packaging controls the “genome’s guardian”

Simplified models, deeper insights: Coarse-grained models unlock new potential for ionic liquid simulations

Gorillas’ personal circumstances shape their aggression towards groupmates

Which signalling pathways in the cell lead to possible therapies for Parkinson's disease

Identifying landslide threats using hydrological predictors

First graders who use more educational media spend more time reading

Exploring the meaning in life through phenomenology and philosophy

[Press-News.org] Heart separation device improves 3 year outcomes in heart failure patients