PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Even in normal range, high blood sugar linked to brain shrinkage

2012-09-04
(Press-News.org) MINNEAPOLIS – People whose blood sugar is on the high end of the normal range may be at greater risk of brain shrinkage that occurs with aging and diseases such as dementia, according to new research published in the September 4, 2012, print issue of Neurology®, the medical journal of the American Academy of Neurology.

"Numerous studies have shown a link between type 2 diabetes and brain shrinkage and dementia, but we haven't known much about whether people with blood sugar on the high end of normal experience these same effects," said study author Nicolas Cherbuin, PhD, with Australian National University in Canberra.

The study involved 249 people age 60 to 64 who had blood sugar in the normal range as defined by the World Health Organization. The participants had brain scans at the start of the study and again an average of four years later.

Those with higher fasting blood sugar levels within the normal range and below 6.1 mmol/l (or 110 mg/dL) were more likely to have a loss of brain volume in the areas of the hippocampus and the amygdala, areas that are involved in memory and cognitive skills, than those with lower blood sugar levels. A fasting blood sugar level of 10.0 mmol/l (180 mg/dL) or higher was defined as diabetes and a level of 6.1 mmol/l (110 mg/dL) was considered impaired, or prediabetes.

After controlling for age, high blood pressure, smoking, alcohol use and other factors, the researchers found that blood sugar on the high end of normal accounted for six to 10 percent of the brain shrinkage.

"These findings suggest that even for people who do not have diabetes, blood sugar levels could have an impact on brain health," Cherbuin said. "More research is needed, but these findings may lead us to re-evaluate the concept of normal blood sugar levels and the definition of diabetes."

### The study was supported by the National Health and Medical Research Council Australia and the Australian Rotary Health Research Fund.

To learn more about the aging brain, visit http://www.aan.com/patients.

The American Academy of Neurology, an association of more than 25,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer's disease, stroke, migraine, multiple sclerosis, brain injury, Parkinson's disease and epilepsy.

For more information about the American Academy of Neurology, visit http://www.aan.com or find us on Facebook, Twitter, Google+ and YouTube.


ELSE PRESS RELEASES FROM THIS DATE:

Little evidence of health benefits from organic foods, Stanford study finds

2012-09-04
STANFORD, Calif. — You're in the supermarket eyeing a basket of sweet, juicy plums. You reach for the conventionally grown stone fruit, then decide to spring the extra $1/pound for its organic cousin. You figure you've just made the healthier decision by choosing the organic product — but new findings from Stanford University cast some doubt on your thinking. "There isn't much difference between organic and conventional foods, if you're an adult and making a decision based solely on your health," said Dena Bravata, MD, MS, the senior author of a paper comparing the nutrition ...

Tigers take the night shift to coexist with people

Tigers take the night shift to coexist with people
2012-09-04
Tigers don't have a reputation for being accommodating, but a new study indicates that the feared and revered carnivores in and around a world-renowned park in Nepal are taking the night shift to better coexist with their human neighbors. The revelation that tigers and people are sharing exactly the same space – such as the same roads and trails – of Chitwan National Park flies in the face of long-held convictions in conservation circles. It also underscores how successful conservation efforts need sciences that takes into account both nature and humans. "As our planet ...

Reciprocity an important component of prosocial behavior

2012-09-04
While exchanging favors with others, humans tend to think in terms of tit-for-tat, an assumption easily extended to other animals. As a result, reciprocity is often viewed as a cognitive feat requiring memory, perhaps even calculation. But what if the process is simpler, not only in other animals but in humans as well? Researchers at the Yerkes National Primate Research Center, Emory University, have determined monkeys may gain the advantages of reciprocal exchange of favors without necessarily keeping precise track of past favors. Malini Suchak, a graduate student at ...

Mathematics or memory? Stanford study charts collision course in brain

2012-09-04
STANFORD, Calif. — You already know it's hard to balance your checkbook while simultaneously reflecting on your past. Now, investigators at the Stanford University School of Medicine — having done the equivalent of wire-tapping a hard-to-reach region of the brain — can tell us how this impasse arises. The researchers showed that groups of nerve cells in a structure called the posterior medial cortex, or PMC, are strongly activated during a recall task such as trying to remember whether you had coffee yesterday, but just as strongly suppressed when you're engaged in solving ...

Mass spec makes the clinical grade

2012-09-04
RICHLAND, Wash. -- Combining two well-established analytic techniques and adding a twist identifies proteins from blood with as much accuracy and sensitivity as the antibody-based tests used clinically, researchers report this week in Proceedings of the National Academy of Sciences Early Edition online. The technique should be able to speed up development of diagnostic tests and treatments based on proteins specific to certain diseases. The team of scientists at the Department of Energy's Pacific Northwest National Laboratory found that their technique, called PRISM, ...

High doses of Vitamin D help tuberculosis patients recover more quickly

2012-09-04
For decades before antibiotics became generally available, sunshine was used to treat tuberculosis, with patients often being sent to Swiss clinics to soak up the sun's healing rays. Now, for the first time scientists have shown how and why heliotherapy might, indeed, have made a difference. A study led by researchers at Queen Mary, University of London, conducted in collaboration with the Medical Research Council's National Institute for Medical Research, has shown that high doses of vitamin D, given in addition to antibiotic treatment, appear to help patients with tuberculosis ...

Prenatal maternal smoking associated with increased risk of adolescent obesity

2012-09-04
CHICAGO – Prenatal exposure to maternal cigarette smoking appears associated with an increased risk for adolescent obesity, and is possibly related to subtle structural variations in the brain that create a preference for eating fatty foods, according to a report published Online First by Archives of General Psychiatry, a JAMA Network publication. "Prenatal exposure to maternal cigarette smoking is a well-established risk factor for obesity, but the underlying mechanisms are not known," the authors write as background information. "Preference for fatty foods, regulated ...

Study details bullying involvement for adolescents with autism spectrum disorder

2012-09-04
CHICAGO – A study based on information collected from 920 parents suggests an estimated 46.3 percent of adolescents with an autism spectrum disorder were the victims of bullying, according to a report published Online First by Archives of Pediatrics & Adolescent Medicine, a JAMA Network publication. Bullying involves negative actions toward a peer and is characterized by a power imbalance – physical, social or cognitive – between the victim and the perpetrator. Relatively little research has examined bullying involvement among adolescents with an autism spectrum disorder ...

Study suggests possible association between cardiovascular disease, chemical exposure

2012-09-04
CHICAGO – Exposure to perfluorooctanoic acid (PFOA), a manmade chemical used in the manufacture of some common household products, appears to be associated with cardiovascular disease and peripheral arterial disease in a study of 1,216 individuals, according to a report published Online First by Archives of Internal Medicine, a JAMA Network publication. Surveys have suggested that PFOA (widely used in the manufacture of products such as lubricants, polishes, paper and textile coatings, and food packaging) is detectable in the blood of more than 98 percent of the U.S. ...

Study examines association between Parkinson disease, cancer

2012-09-04
CHICAGO – A study that used a Utah genealogic database and a statewide cancer registry to examine the relationship between Parkinson disease (PD) and cancer suggests an increased risk of prostate cancer and melanoma in patients with PD and their relatives, according to a report published Online First by Archives of Neurology, a JAMA Network publication. Neurodegenerative diseases, in particular PD, may share common pathogenic mechanisms with some cancers, according to the study background. "Identifying a genetic relationship between PD and cancer is critical to understanding ...

LAST 30 PRESS RELEASES:

AI can spot which patients need treatment to prevent vision loss in young adults

Half of people stop taking popular weight-loss drug within a year, national study finds

Links between diabetes and depression are similar across Europe, study of over-50s in 18 countries finds

Smoking increases the risk of type 2 diabetes, regardless of its characteristics

Scientists trace origins of now extinct plant population from volcanically active Nishinoshima

AI algorithm based on routine mammogram + age can predict women’s major cardiovascular disease risk

New hurdle seen to prostate screening: primary-care docs

MSU researchers explore how virtual sports aid mental health

Working together, cells extend their senses

Cheese fungi help unlock secrets of evolution

Researchers find brain region that fuels compulsive drinking

Mental health effects of exposure to firearm violence persist long after direct exposure

Research identifies immune response that controls Oropouche infection and prevents neurological damage

University of Cincinnati, Kent State University awarded $3M by NSF to share research resources

Ancient DNA reveals deeply complex Mastodon family and repeated migrations driven by climate change

Measuring the quantum W state

Researchers find a way to use antibodies to direct T cells to kill Cytomegalovirus-infected cells

Engineers create mini microscope for real-time brain imaging

Funding for training and research in biological complexity

The Journal of Nuclear Medicine Ahead-of-Print Tip Sheet: September 12, 2025

ISSCR statement on the scientific and therapeutic value of human fetal tissue research

Novel PET tracer detects synaptic changes in spinal cord and brain after spinal cord injury

Wiley advances Knowitall Solutions with new trendfinder application for user-friendly chemometric analysis and additional enhancements to analytical workflows

Benchmark study tracks trends in dog behavior

OpenAI, DeepSeek, and Google vary widely in identifying hate speech

Research spotlight: Study identifies a surprising new treatment target for chronic limb threatening ischemia

Childhood loneliness and cognitive decline and dementia risk in middle-aged and older adults

Parental diseases of despair and suicidal events in their children

Acupuncture for chronic low back pain in older adults

Acupuncture treatment improves disabling effects of chronic low back pain in older adults

[Press-News.org] Even in normal range, high blood sugar linked to brain shrinkage