PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Age, not underlying diagnosis, key factor in weight gain in children after tonsillectomy

2012-09-12
(Press-News.org) Potentially worrisome weight gains following tonsillectomy occur mostly in children under the age of 6, not in older children, a study by Johns Hopkins experts in otolaryngology- head and neck surgery shows.

Sudden increases in body mass index, or BMI, have been routinely observed for months after some of the more than half-million surgeries performed annually in the United States to remove the sore and swollen tissues at the back of the throat.

The Johns Hopkins study, in 115 children in the Baltimore region, is believed to be the first to dispel long-held beliefs that such weight gains occurred mostly in children whose tonsils were removed as primary treatment for diagnosed sleep apnea, when the swollen, paired tissues partially obstruct breathing and disrupt sleep. It is also believed to be the largest study to analyze weight gain specific to every child's age group, from 1 through 17.

Although researchers have yet to pinpoint the underlying cause of the weight-gain phenomena, they did find that it happened at the same rate in the 85 children who had the surgery for obstructive sleep apnea as in the 30 who had it due to recurrent episodes of tonsil inflammation.

Senior study investigator, otolaryngologist and sleep medicine expert Stacey Ishman, M.D., M.P.H., says her team's study findings, scheduled to be presented Sept. 12 at the annual meeting of the American Academy of Otolaryngology—Head and Neck Surgeons in Washington, D.C., should help alleviate rising concerns among many parents whose adolescent children are already overweight that tonsillectomy may aggravate the problem; or start one in normal weight kids. Recent surveys have shown that record numbers of American children, as many as one-third, are overweight or obese.

"Our study results show that parents' current concerns about weight gain are serious, but only underweight or normal weight children between the ages of 2 and 6 are most likely to gain even more weight, not older children," says Ishman, an assistant professor at the Johns Hopkins University School of Medicine.

"Parents with overweight adolescent children need not fear tonsillectomy, and those with younger, normal weight and overweight children just really need to closely watch their child's diet following surgery, and make caloric adjustments," says Ishman, who has performed hundreds of the roughly 30-minute procedures that typically require a general anesthetic.

In the study, researchers analyzed the medical records of children between the ages of 6 months and 18 years who had had their tonsils removed at the Johns Hopkins Outpatient Center between 2008 and 2011. Researchers looked only at those medical records for children who had been routinely examined for at least six months after their procedure, with detailed measurements of any possible weight gain, which were averaged and compared based on a formula involving age, gender and height. All also had a history of recurrent tonsillitis or obstructive sleep apnea, as strictly determined by an individual sleep study analysis.

Results showed an averaged post-surgical weight gain of 2 to 5 pounds – or a 1.0- to 1.2-point increase in averaged BMI scores—but the gains were not dependent on whether the underlying condition was inflammation or sleep apnea. Only age mattered, researchers say, after discounting gender and height.

Ishman says that while such weight gains might appear small, in these children's small bodies, whose initial weight was between 22 and 60 pounds (or between 10 to 30 kilos), "a 10 percent weight gain can be quite worrisome."

Results showed a normal weight, 5-year-old boy, weighing 40 pounds (or 18 kilos) and measuring 42 inches tall, who gained 3 pounds after tonsillectomy, would move from the 68th percentile to the 89th percentile in their age-weight group, and become overweight. For an underweight 5-year-old boy of similar height, originally weighing 34 pounds (15 kilos), the same 3-pound weight gain would shift them from the 24th percentile group to the 28th percentile, moving them closer to a normal weight.

However, she says, in an overweight 10-year-old boy, already weighing 90 pounds (41 kilos) and 55 inches tall, there was no weight gain post tonsillectomy, and he remained in the 92nd percentile group, meaning his poor condition did not worsen.

Ishman says her team's next steps are to gain a better understanding of why and how children's age affects weight gain post-tonsillectomy. She already has plans to monitor children immediately after surgery to find out what factors or interventions may help underweight children gain pounds, while helping those who are overweight to not get any bigger.

Since 2002 tonsillectomy has been recommended by the American Academy of Pediatrics as the primary treatment for obstructive sleep apnea, as sleeping aids and drug therapies are not as effective. Studies have shown that if left untreated, sleep apnea can lead to long-term health problems, including increased heart and lung diseases, even death.

###

Funding support for this study was provided by The Johns Hopkins Hospital.

In addition to Ishman, other Johns Hopkins researchers involved in this study were David Smith, M.D., Ph.D., and Emily Boss, M.D., M.P.H. Other study co-investigators included Ami Vikani, B.S., at the George Washington University School of Medicine, in Washington, D.C.; and Fernando Aguirre-Amezquita, M.D., at Escuela de Medicina Ignacio A. Santos de Monterrey, in Mexico.

For more information, go to:
http://www.hopkinsmedicine.org/otolaryngology/our_team/faculty/ishman.html
http://www.entannualmeeting.org/12/

END



ELSE PRESS RELEASES FROM THIS DATE:

A celestial witch's broom?

A celestial witchs broom?
2012-09-12
The Pencil Nebula is pictured in a new image from ESO's La Silla Observatory in Chile. This peculiar cloud of glowing gas is part of a huge ring of wreckage left over after a supernova explosion that took place about 11 000 years ago. This detailed view was produced by the Wide Field Imager on the MPG/ESO 2.2-metre telescope. Despite the tranquil and apparently unchanging beauty of a starry night, the Universe is far from being a quiet place. Stars are being born and dying in an endless cycle, and sometimes the death of a star can create a vista of unequalled beauty as ...

Studies shed light on how to reduce the amount of toxins in plant-derived foods

2012-09-12
A number of environmental toxins pose considerable health threats to humans, and the heavy metal cadmium (Cd) ranks high on the list. Most of us are exposed to it through plant-derived foods such as grains and vegetables. Now, new research offers ways in which investigators can reduce the amount of Cd found in the food we eat, according to a review published online September 12th in the Cell Press journal Trends in Plant Science. "Cadmium is virtually everywhere in the environment, and it is taken up into the human body and bioaccumulates for decades in the kidney," ...

Gut bacteria increase fat absorption

2012-09-12
Baltimore, MD —You may think you have dinner all to yourself, but you're actually sharing it with a vast community of microbes waiting within your digestive tract. A new study from a team including Carnegie's Steve Farber and Juliana Carten reveals that some gut microbes increase the absorption of dietary fats, allowing the host organism to extract more calories from the same amount of food. Previous studies showed gut microbes aid in the breakdown of complex carbohydrates, but their role in dietary fat metabolism remained a mystery, until now. The research is published ...

Sandia, OurEnergyPolicy.org release 'Goals of Energy Policy' poll results

Sandia, OurEnergyPolicy.org release Goals of Energy Policy poll results
2012-09-12
LIVERMORE, Calif.— U.S. energy policy should simultaneously pursue security of its energy supply, economic stability and reduced environmental impacts, says a national poll of energy professionals jointly prepared by Sandia National Laboratories and OurEnergyPolicy.org. The findings of the national poll, "The Goals of Energy Policy," show that the vast majority — more than 85 percent — of the 884 energy professionals surveyed prefer policymaking that pursues all three goals at once. The poll asked the experts to allocate 100 points, representing a 100 percent policymaking ...

New paper addresses causes of shattering glass cookware; Margin of safety described as 'borderline'

2012-09-12
A new paper appearing in the September 2012 edition of the Bulletin of The American Ceramic Society for the first time provides a scientific explanation of why some glass cookware sold in the United States is more susceptible than others to "explosive" shattering and the possibility of exposing consumers to injury from flying glass shards. Clear glass baking dishes and pots are a staple in many households around the world and have been since they were first introduced in 1915 to consumers by the Corning Glass Works, which created the Pyrex brand name. The original Pyrex ...

Old deeds, witness trees offer glimpse of pre-settlement forest in West Virginia

2012-09-12
PARSONS, W. Va., September 12, 2012 – Using old deeds and witness trees, a U.S. Forest Service scientist has created a glimpse of the composition of the forests that covered today's Monongahela National Forest before settlement and logging changed the landscape. "European Settlement-Era Vegetation of the Monongahela National Forest, West Virginia" describes how a Forest Service scientist and her West Virginia University colleague answered questions about the composition of early forests using a unique dataset. The dataset was built with original deeds, metes and bounds ...

Predicting a die throw

2012-09-12
Vegas, Monte Carlo, and Atlantic City draw people from around the world who are willing to throw the dice and take their chances. Researchers from the Technical University of Lodz, Poland, have spotted something predictable in the seemingly random throw of the dice. By applying chaos theory and some high school level mechanics, they determined that by knowing the initial conditions – such as the viscosity of the air, the acceleration of gravity, and the friction of the table – it should be possible to predict the outcome when rolling the dice. The researchers created ...

A carefully scheduled high-fat diet resets metabolism and prevents obesity

A carefully scheduled high-fat diet resets metabolism and prevents obesity
2012-09-12
New research from the Hebrew University of Jerusalem shows that a carefully scheduled high-fat diet can lead to a reduction in body weight and a unique metabolism in which ingested fats are not stored, but rather used for energy at times when no food is available. The research was conducted by Prof. Oren Froy along with Prof. Zecharia Madar, research student Yoni Genzer and research fellow Dr. Hadas Sherman at the Institute of Biochemistry, Food Science and Nutrition, at the Hebrew University's Robert H. Smith Faculty of Agriculture, Food and Environment. The results ...

Epigenetics emerges powerfully as a clinical tool

Epigenetics emerges powerfully as a clinical tool
2012-09-12
The research team led by Manel Esteller, director of the Cancer Epigenetics and Biology Program at the Bellvitge Biomedical Research Institute (IDIBELL), professor of genetics at the University of Barcelona and ICREA researcher, has updated the latest findings in applied epigenetics in a review paper published in Nature Reviews Genetics. There is a growing need for better biomarkers that allow early detection of human diseases, especially cancer. The markers can improve primary prevention, diagnosis and prognosis of disease. Furthermore, it is possible to predict which ...

First pediatric study to look at the role of vitamin D in critical illness

2012-09-12
OTTAWA, Canada, September 12, 2012—Vitamin D is increasingly being recognized as important for good health. Vitamin D is a hormone made in the skin following sun exposure or acquired from diet and supplement intake. Previous medical research has shown that low body levels of vitamin D make people more susceptible to problems such as bone fractures, poor mental health and infections like the common cold. Until recently, there had been little consideration given to the role of vitamin D in more severe diseases, which is why Dr. Dayre McNally's recent publication in the esteemed ...

LAST 30 PRESS RELEASES:

CMD-OPT model enables the discovery of a potent and selective RIPK2 inhibitor as preclinical candidate for the treatment of acute liver injury

Melatonin receptor 1a alleviates sleep fragmentation-aggravated testicular injury in T2DM by suppression of TAB1/TAK1 complex through FGFR1

Single-cell RNA sequencing reveals Shen-Bai-Jie-Du decoction retards colorectal tumorigenesis by regulating the TMEM131–TNF signaling pathway-mediated differentiation of immunosuppressive dendritic ce

Acta Pharmaceutica Sinica B Volume 15, Issue 7 Publishes

New research expands laser technology

Targeted radiation offers promise in patients with metastasized small cell lung cancer to the brain

A high clinically translatable strategy to anti-aging using hyaluronic acid and silk fibroin co-crosslinked hydrogels as dermal regenerative fillers

Mount Sinai researchers uncover differences in how males and females change their mind when reflecting on past mistakes

CTE and normal aging are difficult to distinguish, new study finds

Molecular arms race: How the genome defends itself against internal enemies

Tiny chip speeds up antibody mapping for faster vaccine design

KTU experts reveal why cultural heritage is important for community unity

More misfolded proteins than previously known may contribute to Alzheimer’s and dementia

“Too much going on”: Autistic adults overwhelmed by non-verbal social cues

What’s driving America’s deep freezes in a warming world?

A key role of brain protein in learning and memory is deciphered by scientists

Heart attacks don’t follow a Hollywood script

Erin M. Schuman wins 2026 Nakasone Award for discovery on neural synapse function and change during formation of memories

Global ocean analysis could replace costly in-situ sound speed profiles in seafloor positioning, study finds

Power in numbers: Small group professional coaching reduces rates of physician burnout by nearly 30%

Carbon capture, utilization, and storage: A comprehensive review of CCUS-EOR

New high-temperature stable dispersed particle gel for enhanced profile control in CCUS applications

State gun laws and firearm-related homicides and suicides

Use of tobacco and cannabis following state-level cannabis legalization

Long-term obesity and biological aging in young adults

Eindhoven University of Technology and JMIR Publications announce unlimited open access publishing agreement

Orphan nuclear receptors in metabolic dysfunction-associated steatotic liver disease development

A technological breakthrough for ultra-fast and greener AI

Pusan National University researchers identify key barriers hindering data-driven smart manufacturing adoption

Inking heterometallic nanosheets: A scalable breakthrough for coating, electronics, and electrocatalyst applications

[Press-News.org] Age, not underlying diagnosis, key factor in weight gain in children after tonsillectomy