(Press-News.org) MINNEAPOLIS – Research shows that use of popular antidepressants is linked to an increased risk of some strokes caused by bleeding in the brain, but that the risk is low, according to a multi-study analysis published in the October 17, 2012, online issue of Neurology®, the medical journal of the American Academy of Neurology.
For the research, scientists analyzed all of the studies that have looked at antidepressant use and stroke, which included 16 studies with more than 500,000 total participants. They found that people taking selective serotonin reuptake inhibitors (SSRIs), which are the most commonly used antidepressants, were 50 percent more likely to have an intracranial hemorrhage than those not taking the antidepressants and about 40 percent more likely to have an intracerebral hemorrhage.
But study author Daniel G. Hackam, MD, PhD, FRCPC, of Western University in London, Ontario, said the findings should be viewed with caution. "Because these types of strokes are very rare, the actual increased risk for the average person is very low," he said.
An estimated 24.6 of these strokes occur per 100,000 people per year. According to the research, the use of SSRIs would increase the risk by one additional stroke per 10,000 people per year.
"Overall, these results should not deter anyone from taking an SSRI when it is needed," Hackam said. "In general these drugs are safe, and obviously there are risks to having depression go untreated. But doctors might consider other types of antidepressants for people who already have risk factors for these types of strokes, such as those taking blood thinners, people who have had similar strokes already or those with severe alcohol abuse."
###To learn more about stroke, visit http://www.aan.com/patients.
The American Academy of Neurology, an association of more than 25,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer's disease, stroke, migraine, multiple sclerosis, brain injury, Parkinson's disease and epilepsy.
For more information about the American Academy of Neurology, visit http://www.aan.com or find us on Facebook, Twitter, Google+ and YouTube.
Media Contacts:
Rachel Seroka, rseroka@aan.com, (612) 928-6129
Angela Babb, APR, ababb@aan.com, (612) 928-6102
Antidepressants linked to increased risk of stroke, but risk is low
2012-10-18
ELSE PRESS RELEASES FROM THIS DATE:
Depression and shortened telomeres increased bladder cancer mortality
2012-10-18
ANAHEIM, Calif. — The combination of shortened telomeres, a biological marker of aging associated with cancer development, and elevated depression significantly impacted bladder cancer mortality, according to data presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held here Oct. 16-19, 2012.
"We found that patients with bladder cancer with shorter telomeres and high levels of depression symptoms have a threefold increased risk for mortality," said Meng Chen, Ph.D., an epidemiologist at The University of Texas MD Anderson ...
Race, socioeconomics had impact on emergency colorectal cancer diagnosis
2012-10-18
ANAHEIM, Calif. — Twenty-nine percent of patients with colorectal cancer in a nationally representative sample were diagnosed after an emergency, such as an obstruction or perforation of the bowel, according to data presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held here Oct. 16-19, 2012. In addition, African-Americans and those living in high-poverty areas were more likely to present with an emergency diagnosis.
"Overall, there are high rates of emergency presentation of colorectal cancer in the United States," ...
2 components of red meat combined with alteration in DNA repair increase risk for bladder cancer
2012-10-18
ANAHEIM, Calif. — Two components of red meat — dietary protein and dietary iron — may combine to form powerful carcinogens, N-nitroso compounds, which increase risk for bladder cancer. Moreover, individuals with reduced ability to reverse the effects of N-nitroso compounds because of a genetic variation in their RAD52 gene could be at particularly high risk.
Chelsea Catsburg, a doctoral student at the Keck School of Medicine of the University of Southern California, Los Angeles, presented these data at the 11th Annual AACR International Conference on Frontiers in Cancer ...
Routine screening for cervical cancer low among lesbian community
2012-10-18
ANAHEIM, Calif. — Screening for cervical cancer was low among women who self-identified as lesbian — a finding that places them at a potentially elevated risk for the disease, according to data presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held here Oct. 16-19, 2012.
"Despite our knowledge of the value of Pap testing for early detection of treatable cervical abnormalities, lesbians are one subset of women who are not getting screened at recommended rates. In fact, nearly 38 percent of lesbians in our study had not ...
Adhering to lifestyle guidelines reduced mortality in elderly female cancer survivors
2012-10-18
ANAHEIM, Calif. — Achieving and maintaining a healthy body weight, staying physically active and maintaining a healthy diet improved survival after cancer diagnosis in an elderly female cancer survivor population, according to data presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held here Oct. 16-19, 2012.
Researchers examined cancer survivors' adherence to the 2007 World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) guidelines for body weight, physical activity and diet.
"Elderly female ...
Bloodstream infections cut by 44 percent in sickest hospital patients, study concludes
2012-10-18
San Diego, CA (October 17, 2012) – A sweeping study on the issue of antibiotic-resistant bacteria in hospitals shows that using antimicrobial soap and ointment on all intensive-care patients significantly decreases bloodstream infection. The results, which are being presented for the first time at IDWeek 2012TM, may suggest a major change in health care practice that could help save lives.
The study involved nearly 75,000 patients in 43 mostly community hospitals in 16 states and involved each hospital's own quality improvement team. Working with these teams enabled ...
Leading bone marrow transplant expert recommends significant change to current practice
2012-10-18
SEATTLE – One of the world's leading bone marrow transplant experts is recommending a significant change to current transplant practice for patients who need marrow or adult stem cells from an unrelated donor to treat hematologic malignancies. Fred Appelbaum, M.D., director of the Clinical Research Division at Fred Hutchinson Cancer Research Center, asserts that bone marrow – not circulating, peripheral blood, which is the current norm – should be the source for unrelated donor adult stem cells for most patients who require a transplant. The reason: because there is less ...
Study finds potential new drug therapy for Crohn's disease
2012-10-18
Ustekinumab, an antibody proven to treat the skin condition psoriasis, has now shown positive results in decreasing the debilitating effects of Crohn's Disease, according to researchers at the University of California San Diego, School of Medicine. The study will appear in the October 18, 2012 issue of the New England Journal of Medicine (NEJM).
Results from the clinical trial showed ustekinumab (Stelara) increased clinical response and remission in patients suffering from moderate-to-severe Crohn's Disease - a form of inflammatory bowel disease (IBD) that can lead ...
Bus service for qubits
2012-10-18
Qubit-based computing exploiting spooky quantum effects like entanglement and superposition will speed up factoring and searching calculations far above what can be done with mere zero-or-one bits. To domesticate quantum weirdness, however, to make it a fit companion for mass-market electronic technology, many tricky bi-lateral and multi-lateral arrangements---among photons, electrons, circuits, cavities, etc.---need to be negotiated.
A new milestone in this forward march: a Princeton-Joint Quantum Institute (JQI) collaboration announces the successful excitation ...
Study: Nearly 4 out of 10 lesbians not routinely screened for cervical cancer
2012-10-18
ANAHEIM, Calif. – Oct.17, 2012. Nearly 38 percent of lesbians polled in a national survey were not routinely screened for cervical cancer, putting them at risk of developing a highly preventable cancer, according to a University of Maryland School of Medicine study being presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research. Cervical cancer is caused by a sexually transmitted virus, the human papillomavirus (HPV), and can be detected through regular Pap smears.
The percentage of lesbians not being screened as recommended ...