PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Soy intake associated with lower recurrence of breast cancer in hormone-sensitive cancers

2010-10-19
(Press-News.org) Post-menopausal breast cancer patients with hormone-sensitive cancers who consumed high amounts of soy isoflavones had a lower risk of recurrence, found a research study published in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj091298.pdf.

Soy isoflavones are similar to estrogen in chemical structure and may stimulate or inhibit estrogen-like action in tissues. Consumption of soy isoflavones, found in soybeans and soy products, has increased in recent years and there are concerns about the effect of soy consumption on women with estrogen and progesterone receptor positive breast cancer as tumour growth is dependent on estrogen.

The study, by researchers at the Cancer Hospital of Harbin Medical University, Harbin, China, involved 524 women who had surgery for breast cancer and were followed afterwards for between five to six years. Since little is known about the effects of soy isoflavones on breast cancer patients receiving adjuvant endocrine therapy, the researchers sought to understand its impact in these patients.

"Compared with postmenopausal patients in the lowest quartile of soy isoflavone intake (less than 15.2 mg/day), those in the highest quartile (more than 42.3 mg/day) had a significantly lower risk of recurrence," writes Dr. Qingyan Zhang with coauthors.

"The recurrence rate of estrogen- and progesterone- positive breast cancer was 12.9% lower among patients in the highest quartile of soy isoflavone intake than among those in the lowest quartile and was 18.7% lower for patients receiving anastrozole therapy in the highest quartile," they state.

However, there was no effect on overall survival in postmenopausal women and no association between soy intake and survival in premenopausal women.

The authors conclude that while this finding is potentially important regarding soy intake, large multicentre clinical trials are needed to provide more data.

INFORMATION:

END



ELSE PRESS RELEASES FROM THIS DATE:

Analysis indicates a third H1N1 pandemic wave unlikely in 2010

2010-10-19
Analysis of H1N1 antibody levels (seroprotection rates) after the 2009 pandemic suggest that a third wave is unlikely in 2010, although adults over age 50, particularly those with chronic conditions, should be immunized for the fall flu season, states a research paper in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj100910.pdf. The study, by researchers from the BC Centre for Disease Control, University of British Columbia and BC Biomedical Laboratories, compared blood levels of antibodies against the H1N1 influenza ...

Lessons learned from the H1N1 pandemic

2010-10-19
The H1N1 pandemic influenza provided several important lessons that may help in preparing for future influenza outbreaks, write Drs. Donald Low and Allison McGeer in an analysis in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj100900.pdf. Although the death rate was lower than initially projected, the years of life lost was significant because "deaths from the 2009 pandemic were skewed toward younger ages than deaths from seasonal influenza," write the authors, both affiliated with Mount Sinai Hospital and the University ...

Tackling cognitive deficits in Alzheimer's disease: 1 'STEP' at a time

2010-10-19
Lowering levels of a key protein involved in regulating learning and memory—STtriatal-Enriched tyrosine Phosphatase (STEP)—reversed cognitive deficits in mice with Alzheimer's disease, Yale School of Medicine researchers report in the October 18 issue of Proceedings of the National Academy of Sciences. "This finding provides a rationale for drug discovery and for developing therapeutic agents that could inhibit STEP proteins and might improve the outlook for Alzheimer's disease patients," said senior author of the study Paul Lombroso, M.D., professor in the Yale Child ...

Beta carotene and retinitis pigmentosa

2010-10-19
CHICAGO—Today's Scientific Program of the 2010 American Academy of Ophthalmology (AAO) - Middle East-Africa Council of Ophthalmology (MEACO) Joint Meeting includes a report on beta carotene's ability to improve vision in people with certain incurable retinal diseases. The AAO-MEACO meeting–the world's largest, most comprehensive ophthalmic education conference–is in session October 16 through 19 at McCormick Place, Chicago. 9-cis Beta-Carotene Mat Boost Vision in Some Patients with Incurable Retinal Disease Retinitis pigmentosa (RP) is a cluster of hereditary disorders ...

New evidence of the power of open access

2010-10-19
New findings settle one of the arguments about Open Access (OA) research publications: Are they more likely to be cited because they were made OA, or were they made OA because they were more likely to be cited? The study, which will be published in PLoS ONE on the first day of Open Access Week (18 October), was carried out by a bi-national team of researchers from the University of Southampton's School of Electronics and Computer Science (ECS) in the UK and l'Université du Québec à Montréal in Canada. The results show that the OA citation impact advantage is just ...

Surgical complications drop at hospitals that share patient safety data

2010-10-19
ANN ARBOR, Mich. – Michigan hospitals reduced surgical complications by nearly 10 percent at a time when the rest of the nation saw no change in complication rates, according to a new study out next week in the Archives of Surgery. Complications dropped at hospitals participating in what's called the Michigan Surgical Quality Collaborative, a group of 16 hospitals led by the University of Michigan Health System that agreed to pool data and share information about what keeps patients safe. The fewer patients suffering ventilator associated pneumonias alone, among the ...

News and insights in gastroenterology presented at the ACG's 75th Annual Meeting

2010-10-19
Bethesda, Maryland (October 14, 2010) – Many of the world's preeminent gastroenterologists will gather for the American College of Gastroenterology's (ACG) 75th Annual Scientific Meeting at the Henry B. Gonzalez Convention Center in San Antonio, Texas starting Monday October 18, 2010, to review the latest scientific advances in gastrointestinal research, treatment of digestive diseases and clinical practice management. Innovative technologies for the diagnosis and treatment of digestive diseases; insights into digestive health conditions, their causes and how they impact ...

Allergy drug found to clear condition but not symptoms of throat disease

2010-10-19
ROCHESTER, Minn. -- A group of Mayo Clinic (http://www.mayoclinic.org/about/) researchers conducted the first controlled trial of swallowed fluticasone nasal spray (also known as Flonase) on people with the allergic esophageal condition called eosinophilic esophagitis (http://www.mayoclinic.org/eosinophilic-esophagitis/). Research showed that the aerosolized swallowed allergy drug helped treat the cause of the throat condition, but symptoms lingered. The researchers' findings were presented today at the Annual Scientific Meeting of the American College of Gastroenterology ...

The protein NOS2 isn't good for ER-negative breast cancer patients

2010-10-19
Breast cancers can be divided into different subtypes based on several criteria, including whether or not they express the protein to which the female hormone estrogen binds; that is, the estrogen receptor (ER). Patients with ER-negative breast tumors have a worse outlook than those with ER-positive breast tumors. However, even among ER-negative breast tumors, those characterized as basal-like are the most aggressive and difficult to treat. New therapeutic targets for this subtype of breast cancer are urgently needed. Now, a team of researchers, led by Stefan Ambs, at the ...

JCI online early table of contents: Oct. 18, 2010

2010-10-19
EDITOR'S PICK: The protein NOS2 isn't good for ER-negative breast cancer patients Breast cancers can be divided into different subtypes based on several criteria, including whether or not they express the protein to which the female hormone estrogen binds; that is, the estrogen receptor (ER). Patients with ER-negative breast tumors have a worse outlook than those with ER-positive breast tumors. However, even among ER-negative breast tumors, those characterized as basal-like are the most aggressive and difficult to treat. New therapeutic targets for this subtype of breast ...

LAST 30 PRESS RELEASES:

Scientists glimpse how enzymes “dance” while they work, and why that’s important

California partnership aided COVID-19 response and health equity, report finds

University of Oklahoma secures $19.9 million for revolutionary radar technology

Study finds restoring order to dividing cancer cells may prevent metastasis

High-accuracy tumor detection with label-free microscopy and neural networks

Wayne State research reveals fetuses exposed to Zika virus have long-term immune challenges

Researchers deconstruct chikungunya outbreaks to improve prediction and vaccine development

Study finds one-year change on CT scans linked to future outcomes in fibrotic lung disease

Discovery of a novel intracellular trafficking pathway in plant cells

New tool helps forecast volcano slope collapses and tsunamis

Molecular coating cleans up noisy quantum light

From Parkinson's to rare diseases, discovered a key switch for cellular health

Tiny sugars in the brain disrupt emotional circuits, fueling depression

Mini-organs reveal how the cervix defends itself

Africa, climate, and food: How to feed a continent without increasing its carbon footprint

Researchers demonstrates substrate design principles for scalable superconducting quantum materials

How better software choices could cut US health care costs

Concussion history in NCAA athletes yields mixed health outcomes

Counting plastic reveals hidden waste and sparks action

Warming oceans may pose a serious threat to American lobsters

Deaths from drug-induced unintentional injury rise across the US

In car crashes with pedestrians, age and zip code may predict extent of traumatic injuries

AI optimizes evacuation, diagnosis, and treatment of wounded soldiers in Ukraine

Mastectomy linked to worsened sexual health, body image after surgery

Drop in credit score after cancer diagnosis linked to increased mortality, study shows

Use of weight loss drugs before bariatric surgery has soared in recent years, study finds

EMS call times in rural areas take at least 20 minutes longer than national average

Rectal bleeding in young adults linked to 8.5 times higher risk of colorectal cancer

Hospital closures disproportionately affect socioeconomically disadvantaged communities

Global disparities in premature mortality

[Press-News.org] Soy intake associated with lower recurrence of breast cancer in hormone-sensitive cancers