PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Post-ER care for chest pain reduces risk of heart attack, death

2013-04-02
(Press-News.org) Seeing a doctor within a month of an emergency room visit for chest pain significantly reduced the risk of heart attack or death among high risk patients, according to research published the American Heart Association journal Circulation.

Chest pain is the most common reason people go to the emergency room in developed countries and accounts for more than 5 million ER visits each year in the United States.

The study is the first to demonstrate the importance of follow-up care for chest pain patients after leaving the ER, researchers said. High risk patients in this study were those with previously diagnosed heart disease or diabetes.

"Being discharged from the emergency department is reassuring for patients, but it is critical that they follow up with their doctor to reduce their risks of future heart attacks or premature death," said Dennis T. Ko, M.D., M.Sc., senior author and scientist at the Institute for Clinical Evaluative Sciences, Cardiologist at Sunnybrook Health Sciences Centre in Toronto, Ontario, Canada. "Patients need to advocate for themselves and physicians need to be more diligent about arranging follow-up care."

Researchers analyzed data on 56,767 adults (average age 66, 53 percent men) in Ontario, Canada, who were diagnosed with chest pain in an emergency room between April 2004 and March 2010; had been previously diagnosed with heart disease or diabetes; and didn't require additional hospitalization or die within a month. They tracked data for a median 3.7 years and accounted for differences in key patient characteristics such as age, gender, health status and location.

Among the findings: Only 17 percent of high risk chest pain patients seen in the emergency room were evaluated by cardiologists within a month; 58 percent saw a primary care physicians alone, and 25 percent had no physician follow-up within a month. Patients who followed up with a cardiologist within 30 days were 21 percent less likely to have a heart attack or die within one year, compared with patients who failed to seek additional care within that time. Patients seen by a primary care physician were 7 percent less likely to have a heart attack or die compared to those patients who sought no follow up care. Patients treated by cardiologists received more testing, procedures and medication within 100 days of their ER discharge and had the best health outcomes. Patients seen by their cardiologist were 15 percent less likely to have a heart attack or die within the first year, compared to patients who received follow up care from their primary care physician.

Patients who didn't seek follow-up care within a month received the lowest rate of care and had the worst health outcomes — demonstrating the need to improve follow-up with high risk chest pain patients after they're discharged from the emergency room, Ko said.

The study notes that there are several reasons patients did not receive additional physician follow-up including: patients believing they didn't need additional care and the lack of a coordinated referral system from the emergency department to physicians who can provide follow-up care.

While there is no cost for seeing a physician at follow-up in the Canadian health care system, the barriers for follow up care could include expense in other countries.

"As physicians, we are often so focused on knowing which drug to prescribe or which test to order that we overlook the fact that many patients fail to get follow-up care to begin with," Ko said. "We need systems of care that better identify these patients who are at increased risk because getting that follow-up can significantly reduce their risks of heart attack or premature death."

Because the study focused on high risk patients, the results may not apply to all who have chest pain. Researchers recommend further study that will also investigate economic factors. INFORMATION:

Co-authors are: Andrew Czarnecki, M.D.; Alice Chong, B.Sc.; Douglas S. Lee, M.D., Ph.D.; Michael J. Schull, M.D., M.Sc.; Jack V. Tu, M.D., Ph.D.; Ching Lau, M.D.; and Michael E. Farkouh, M.D., M.Sc.. Author disclosures and sources of funding are on the manuscript. Learn how to Understand Your Risk of Heart Attack For the latest heart and stroke news, follow us on Twitter: @HeartNews.

Statements and conclusions of study authors published in American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect the association's policy or position. The association makes no representation or guarantee as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations are available at http://www.heart.org/corporatefunding.



ELSE PRESS RELEASES FROM THIS DATE:

Understanding statin discontinuation

2013-04-02
Boston, MA-- Despite their well-documented benefits, statins, drugs used to lower cholesterol, are commonly discontinued in routine care. Statin discontinuation has been linked to increased risk for cardiovascular events and death in patients with coronary artery disease; nevertheless, the reasons for discontinuation are only starting to be explored. In a new study from Brigham and Women's Hospital (BWH), researchers examined the role adverse reactions play in statin discontinuation and found that more than 90 percent of the patients who stopped taking a statin due to an ...

Extreme algal blooms: The new normal?

2013-04-02
Washington, D.C.—A research team, led by Carnegie's Anna Michalak, has determined that the 2011 record-breaking algal bloom in Lake Erie was triggered by long-term agricultural practices coupled with extreme precipitation, followed by weak lake circulation and warm temperatures. The team also predicts that, unless agricultural policies change, the lake will continue to experience extreme blooms. The research is published in the online early edition of the Proceedings of the National Academy of Sciences the week of April 1, 2013. "The perfect storm of weather events ...

Record-breaking 2011 Lake Erie algae bloom may be sign of things to come

2013-04-02
ANN ARBOR—The largest harmful algae bloom in Lake Erie's recorded history was likely caused by the confluence of changing farming practices and weather conditions that are expected to become more common in the future due to climate change. Rather than an isolated, one-time occurrence, Lake Erie's monumental 2011 algae bloom was more likely a harbinger of things to come, according to University of Michigan researchers and colleagues from eight other institutions. The interdisciplinary team explored factors that may have contributed to the event and analyzed the likelihood ...

Body Mass Index and coronary heart disease

2013-04-02
Coronary heart disease (CHD) increases with BMI, as well as with age, finds an article published in BioMed Central's open access journal BMC Medicine. The research from the Million Women Study indicates that increased weight increases risk of CHD equivalent to that caused by getting older. Researchers from the University of Oxford followed the health of 1.2 million women from England and Scotland for (on average) almost a decade. Analysis of the data showed that the occurrence of CHD increases with BMI so that every 5 unit increase in BMI, calculated as weight/height2, ...

Tests to predict heart problems may be more useful predictor of memory loss than dementia tests

2013-04-02
MINNEAPOLIS – Risk prediction tools that estimate future risk of heart disease and stroke may be more useful predictors of future decline in cognitive abilities, or memory and thinking, than a dementia risk score, according to a new study published in the April 2, 2013, print issue of Neurology®, the medical journal of the American Academy of Neurology. "This is the first study that compares these risk scores with a dementia risk score to study decline in cognitive abilities 10 years later," said Sara Kaffashian, PhD, with the French National Institute of Health and Medical ...

Eating fish associated with lower risk of dying among older adults

2013-04-02
Boston, MA – Older adults who have higher levels of blood omega-3 levels—fatty acids found almost exclusively in fatty fish and seafood—may be able to lower their overall mortality risk by as much as 27% and their mortality risk from heart disease by about 35%, according to a new study from Harvard School of Public Health (HSPH) and the University of Washington. Researchers found that older adults who had the highest blood levels of the fatty acids found in fish lived, on average, 2.2 years longer than those with lower levels. "Although eating fish has long been considered ...

The metabolic weathervane of cancer

2013-04-02
Highly expressed in various cancers and known for its cytoprotective properties, TRAP1 protein has been identified as a potential target for antitumor treatments. As a result of the research conducted by Len Neckers, from the National Cancer Institute in Bethesda, USA, and Didier Picard, from the University of Geneva (UNIGE), Switzerland, this outlook is now being called into question. The researchers' findings, published in PNAS, describe how TRAP1 disrupts the metabolism of malignant cells, and shows that the quantity of this protein decreases as they progress to a more ...

Loss of tumor suppressor SPOP releases cancer potential of SRC-3

2013-04-02
HOUSTON - (April 1, 2013) – Mutations in a protein called SPOP (speckle-type POZ protein) disarm it, allowing another protein called steroid receptor coactivator-3 (SRC-3) to encourage the proliferation and spread of prostate cancer cells, said researchers led by those at Baylor College of Medicine in a report that appears online in Proceedings of the National Academy of Sciences. Normally SPOP acts as a tumor suppressor gene by marking SRC-3 for destruction, said Dr. Nicholas Mitsiades, assistant professor of medicine – hematology/oncology and molecular and cellular ...

Princess Margaret breast cancer research finds new drug target companion prognostic test for hormone therapy resistance

2013-04-02
(TORONTO, Canada – April 1, 2013) – A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive breast cancer cells that are resistant to hormone therapies such as tamoxifen, aromatase inhibitors or fulvestrant. Resistance to hormone therapy is reported in almost half of ER-positive breast cancer patients and no cure is currently available. The fact that the pathway, called Notch, is a drug target ...

Study examines change in cognitive function following physical, mental activity in older adults

2013-04-02
A randomized controlled trial finds that 12 weeks of physical plus mental activity in inactive older adults with cognitive complaints was associated with significant improvement in cognitive function but there was no difference between intervention and control groups, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication. An epidemic of dementia worldwide is anticipated during the next 40 years because of longer life expectancies and demographic changes. Behavioral interventions are a potential strategy to prevent or delay ...

LAST 30 PRESS RELEASES:

Synchronization in neural nets: Mathematical insight into neuron readout drives significant improvements in prediction accuracy

TLE6 identified as a protein associated with infertility in male mice

Thin lenses have a bright future

Volcanic eruption caused Neolithic people to sacrifice unique "sun stones"

Drug in clinical trials for breast cancer could also treat some blood cancers

Study identifies mechanism underlying increased osteoarthritis risk in postmenopausal females

The material revolution: How USA’s commodity appetite evolved from 1900 to present

Asteroid impact sulfur release less lethal in dinosaur extinction

Study shows seed impact mills clobber waterhemp seed viability

Study links rising suicidality among teen girls to increase in identifying as LGBQ

Mind’s eye: Pineal gland photoreceptor’s 2 genes help fish detect color

Nipah virus: epidemiology, pathogenesis, treatment, and prevention

FDA ban on Red Dye 3 and more are highlighted in Sylvester Cancer's January tip sheet

Mapping gene regulation

Exposure to air pollution before pregnancy linked to higher child body mass index, study finds

Neural partially linear additive model

Dung data: manure can help to improve global maps of herbivore distribution

Concerns over maternity provision for pregnant women in UK prisons

UK needs a national strategy to tackle harms of alcohol, argue experts

Aerobic exercise: a powerful ally in the fight against Alzheimer’s

Cambridge leads first phase of governmental project to understand impact of smartphones and social media on young people

AASM Foundation partners with Howard University Medical Alumni Association to provide scholarships

Protective actions need regulatory support to fully defend homeowners and coastal communities, study finds

On-chip light control of semiconductor optoelectronic devices using integrated metasurfaces

America’s political house can become less divided

A common antihistamine shows promise in treating liver complications of a rare disease complication

Trastuzumab emtansine improves long-term survival in HER2 breast cancer

Is eating more red meat bad for your brain?

How does Tourette syndrome differ by sex?

Red meat consumption increases risk of dementia and cognitive decline

[Press-News.org] Post-ER care for chest pain reduces risk of heart attack, death