Particles changing angle: Unexpected orientation in capillaries
Surprising discovery important for technical spinning processes and for the understanding of vascular stenosis
2013-04-09
(Press-News.org) When small particles flow through thin capillaries, they display an unusual orientation behaviour. This has recently been discovered by a research team led by Prof. Stephan Förster and Prof. Walter Zimmermann (University of Bayreuth, Germany) at the X-ray sources DORIS III and PETRA III of the research centre DESY in Hamburg, Germany. The discovery is of major importance for spinning processes designed for the production of synthetic fibres, and for the understanding of vascular stenosis. The scientists of Bayreuth University, the Radboud University Nijmegen (Netherlands), the Max Planck Institute for Dynamics and Self-Organization in Göttingen (Germany), and DESY report their surprising findings in the scientific journal PNAS.
X-ray experiments make the flow behaviour visible
Rod- or plate-like particles flowing through thin capillaries, usually orientate themselves parallel in relation to the flow direction. Should a capillary display a constriction, this alignment does not change until the particles have reached the narrowest location. As soon as the capillary expands again however, the particles align themselves perpendicular to the flow direction, having changed angle. Not only have scientists discovered this surprising phenomenon, they have also found an explanation. In theoretical calculations they were able to show that within the dilating capillary segment, strong dilating forces appear perpendicular to the flow direction. Such dilating effects a realignment of the particles.
The theoretical calculations were confirmed using micro X-ray experiments at Deutsches Elektronen-Synchrotron DESY. Using the light source PETRA III, highly intensive X-rays were produced measuring merely ten micrometers in diameter. With the help of this narrowly focussed beam it was possible for the first time to observe the streaming behaviour in particularly thin capillaries. The scientists were able to precisely determine the alignment of particles flowing through a constricted capillary. The perpendicular orientation which is taken on after passing the narrowest point remains stable, not changing in the further course of the capillary.
New applications first in the production of high-performance fibres and second with regard to the onset of vascular diseases
The realignment of particles when flowing through narrow points of capillaries is crucial to the understanding of many biological and technical flow processes. One example is the process of spinning, whereby solutions of macromolecules and particles are pressed through fine spinning nozzles. In order to produce fibres characterised by high tear strength and other significant mechanical properties, it is vital that the macromolecules and particles orientate themselves parallel to the flow direction. As recently discovered however, they are aligned perpendicular to the flow direction when leaving the nozzle. This explains why, as has been known for a long time, spun fibres have to be stretched. This stretching ensures the macromolecules and particles (the fibres' building blocks) reassume the desired parallel alignment. The findings recently published in the PNAS make it possible to predict the flow orientation of such building blocks and control it precisely by means of an appropriate design of capillaries and nozzles.
A further area of application is in the field of medicine, insofar as cells and proteins flow through very fine blood vessels. When they realign themselves due to vascular stenosis, agglomeration may occur, resulting in thrombosis or vascular occlusion. The international team of researchers have possibly discovered an important sub-process which contributes significantly to the onset of vascular disease.
International research co-operation
Among the authors of this report published in the PNAS are Prof. Stephan Förster and his team from the Physical Chemistry I department as well as Prof. Walter Zimmermann of the Theoretical Physics I department of the University of Bayreuth, Dr. Julian Thiele (Radboud University Nijmegen), Dr. Dagmar Steinhauser (Max Planck Institute for Dynamics and Self-Organization, Göttingen, and German Institute of Rubber Technology, Hannover) and Dr. Jan Perlich, Dr. Adeline Buffet and Dr. Stephan V. Roth (DESY, Hamburg). The project has been realised with the support of an ERC Advanced Grant from the European Union, which Prof. Stephan Förster received in 2012, and with funding from the German Ministry of Science and Education (Bundesministerium für Bildung und Forschung, BMBF).
INFORMATION: END
ELSE PRESS RELEASES FROM THIS DATE:
2013-04-09
Scientists at Washington University School of Medicine in St. Louis have shown they can coax cells to move toward a beam of light. The feat is a first step toward manipulating cells to control insulin secretion or heart rate using light.
Their research is published April 8 in the Proceedings of the National Academy of Sciences Online Early Edition.
"We have succeeded in using light as a kind of on-off switch to control cells' behavior," says principal investigator N. Gautam, PhD, a professor of anesthesiology. "Much of the way cells behave is due to their ability to ...
2013-04-09
The Gulf of Mexico may have a much greater natural ability to self-clean oil spills than previously believed, according to Terry Hazen, University of Tennessee-Oak Ridge National Laboratory Governor's Chair for Environmental Biotechnology.
The bioremediation expert presented his Deepwater Horizon disaster research findings at the 245th National Meeting and Exposition of the American Chemical Society (ACS), the world's largest scientific society.
Hazen conducted research following the 2010 Deepwater Horizon disaster, which is estimated to have spilled 210 million gallons ...
2013-04-09
April 8, 2013, New York, NY and San Diego Calif. – Proteins that control cell growth are often mutated in cancer, and their aberrant signaling drives the wild proliferation of cells that gives rise to tumors. One such protein, the epidermal growth factor receptor (EGFR), fuels a wide variety of cancers—including a highly malignant brain cancer known as glioblastoma. Yet drugs devised to block its signaling tend to work only for a short while, until the cancer cells adapt to evade the therapy. So far, much of the research examining such drug resistance has focused on how ...
2013-04-09
WASHINGTON, D.C. – April 8, 2013— A team of researchers, led by Marc Freeman, PhD, an early career scientist with the Howard Hughes Medical Institute and associate professor of neurobiology at the University of Massachusetts Medical School have discovered a gene in the fruit fly Drosophila melanogaster that, when mutant, blocks the self-destruction of damaged axons, which could hold clues to treating motor neuron diseases, such as amyotrophic lateral sclerosis (ALS).
A neuron has a very distinctive form – a bush of dendrites that receive signals, an incredibly long axon, ...
2013-04-09
COLUMBIA, Mo. – Although no exact formula for marital bliss exists, a University of Missouri researcher has found that husbands and wives are happier when they share household and child-rearing responsibilities. However, sharing responsibilities doesn't necessarily mean couples divide chores equally, said Adam Galovan, a doctoral student in the MU Department of Human Development and Family Studies.
"Sharing can mean something different to every couple," Galovan said. "It could be taking turns changing diapers or one parent watching the children while the other prepares ...
2013-04-09
Several studies have examined the impact of stress on a pregnancy – both chronic stress, such as workload, and acute stress associated with traumatic events like the 9/11 terrorist attacks. They conclude that stress can lead to adverse birth outcomes, including miscarriage and premature birth.
Few studies, however, assess the impact of continuous military or political stress throughout a pregnancy, says Prof. Liat Lerner-Geva of Tel Aviv University's Sackler Faculty of Medicine and the Women and Children's Health Research Unit at The Gertner Institute for Epidemiology ...
2013-04-09
ROCHESTER, Minn. -- A multidisciplinary team of researchers at Mayo Clinic has developed a new software tool to noninvasively characterize pulmonary adenocarcinoma, a common type of cancerous nodule in the lungs. Results from a pilot study of the computer-aided nodule assessment and risk yield (CANARY) are published in the Journal of Thoracic Oncology.
"Pulmonary adenocarcinoma is the most common type of lung cancer and early detection using traditional computed tomography (CT) scans can lead to a better prognosis," says Tobias Peikert, M.D., a Mayo Clinic pulmonologist ...
2013-04-09
PROVIDENCE, R.I. – A new study by a Rhode Island Hospital researcher has found that traumatic brain injury (TBI) can significantly increase the odds of having major depression, personality impulsivity and post-traumatic stress disorder (PTSD) in patients with psychogenic nonepileptic seizures (PNES). The paper, by W. Curt LaFrance Jr., M.D., M.P.H., director of neuropsychiatry and behavioral neurology, is published online in advance of print in the journal Epilepsia.
"Some patients who sustain a TBI develop seizures," LaFrance said. "Very often, these seizures are believed ...
2013-04-09
WHITE PLAINS, N.Y., APRIL 8, 2013 – A study published today in Obstetrics & Gynecology shows that multistate, hospital-based quality improvement programs can be remarkably effective at reducing early elective deliveries of babies.
The rate of elective early term deliveries (i.e., inductions of labor and Cesarean sections without a medical reason) in a group of 25 participating hospitals fell significantly from 27.8 percent to 4.8 percent during the one-year project period, an 83 percent decline.
The March of Dimes, which partly funded the study, calls the findings ...
2013-04-09
Computer scientists at the University of California, San Diego, have developed an immersive, first-person player video game designed to teach students in elementary to high school how to program in Java, one of the most common programming languages in use today.
The researchers tested the game on a group of 40 girls, ages 10 to 12, who had never been exposed to programming before. They detailed their findings in a paper they presented at the SIGCSE conference in March in Denver. Computer scientists found that within just one hour of play, the girls had mastered some of ...
LAST 30 PRESS RELEASES:
[Press-News.org] Particles changing angle: Unexpected orientation in capillaries
Surprising discovery important for technical spinning processes and for the understanding of vascular stenosis