PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Research harnesses solar-powered proteins to filter harmful antibiotics from water

2013-04-19
(Press-News.org) New research, just published, details how University of Cincinnati researchers have developed and tested a solar-powered nano filter that is able to remove harmful carcinogens and antibiotics from water sources – lakes and rivers – at a significantly higher rate than the currently used filtering technology made of activated carbon.

In the journal "Nano Letters," Vikram Kapoor, environmental engineering doctoral student, and David Wendell, assistant professor of environmental engineering, report on their development and testing of the new filter made of two bacterial proteins that was able to absorb 64 percent of antibiotics in surface waters vs. about 40 percent absorbed by the currently used filtering technology made of activated carbon. One of the more exciting aspects of their filter is the ability to reuse the antibiotics that are captured.

Kapoor and Wendell began development of their new nano filter in 2010 and testing in 2012, with the results reported in a paper titled "Engineering Bacterial Efflux Pumps for Solar-Powered Bioremediation of Surface Waters."

The presence of antibiotics in surface waters is harmful in that it breeds resistant bacteria and kills helpful microorganisms, which can degrade aquatic environments and food chains. In other words, infectious agents like viruses and illness-causing bacteria become more numerous while the health of streams and lakes degrades.

So, according to Wendell, the newly developed nano filters, each much smaller in diameter than a human hair, could potentially have a big impact on both human health and on the health of the aquatic environment (since the presence of antibiotics in surface waters can also affect the endocrine systems of fish, birds and other wildlife).

Surprisingly, this filter employs one of the very elements that enable drug-resistant bacteria to be so harmful, a protein pump called AcrB. Wendell explained, "These pumps are an amazing product of evolution. They are essentially selective garbage disposals for the bacteria. Our innovation was turning the disposal system around. So, instead of pumping out, we pump the compounds into the proteovesicles." (The new filtering technology is called a proteovesicle system.)

One other important innovation was the power source, a light-driven bacterial protein called Delta-rhodopsin which supplies AcrB with the pumping power to move the antibiotics.

The bacterial protein system has a number of advantages over present filtration technology:



The operation of the new filtering technology is powered by direct sunlight vs. the energy-intensive needs for the operation of the standard activated carbon filter.

The filtering technology also allows for antibiotic recycling. After these new nano filters have absorbed antibiotics from surface waters, the filters could be extracted from the water and processed to release the drugs, allowing them to be reused. On the other hand, carbon filters are regenerated by heating to several hundred degrees, which burns off the antibiotics.

The new protein filters are highly selective. Currently used activated carbon filters serve as "catch alls," filtering a wide variety of contaminants. That means that they become clogged more quickly with natural organic matter found in rivers and lakes.

Said Wendell, "So far, our innovation promises to be an environmentally friendly means for extracting antibiotics from the surface waters that we all rely on. It also has potential to provide for cost-effective antibiotic recovery and reuse. Next, we want to test our system for selectively filtering out hormones and heavy metals from surface waters."

In relation to the work published in this paper, Wendell and Kapoor tested their solar-powered nano filter against activated carbon, the present treatment technology standard outside the lab. They tested their innovation in water collected from the Little Miami River.

Using only sunlight as the power source, they were able to selectively remove the antibiotics ampicillin and vancomycin, commonly used human and veterinary antibiotics, and the nucleic acid stain, ethidium bromide, which is a potent carcinogen to humans and aquatic animals.



INFORMATION:



ELSE PRESS RELEASES FROM THIS DATE:

Alternative medicine use by MS patients now mapped

2013-04-19
A major Nordic research project involving researchers from the University of Copenhagen has, for the first time ever, mapped the use of alternative treatment among multiple sclerosis patients - knowledge which is important for patients with chronic disease and the way in which society meets them. People with multiple sclerosis (MS) often use alternative treatments such as dietary supplements, acupuncture and herbal medicine to facilitate their lives with this chronic disease. This is the result of a new study of how MS patients use both conventional and alternative treatments ...

Stress is good thing for parents, babies in squirrel world

2013-04-19
AUDIO: This is a North American red squirrel emitting a territorial vocalization called a "rattle ". Click here for more information. Stressed-out mothers raise stronger, heartier offspring – at least among squirrels. In a new study, international researchers – including University of Guelph biologists – say squirrels tailor their parenting to meet the varied conditions facing their young. For pups born during crowded, stressful times, mama squirrels kick ...

A fresh take on the Horsehead Nebula

2013-04-19
This year marks the 23rd year of observing for the Hubble Space Telescope. Alongside cutting-edge science, the orbiting observatory has produced countless stunning astronomical images. Some of the most striking and beautiful subjects of Hubble's images have been nebulae -- vast interstellar clouds of gas and dust. This new Hubble image, captured and released to celebrate this milestone, shows part of the sky in the constellation of Orion (The Hunter). Rising like a giant seahorse from turbulent waves of dust and gas is the Horsehead Nebula, otherwise known as Barnard ...

From blank round to a potently active substance?

2013-04-19
A long-forgotten candidate for antiviral therapy is undergoing a renaissance: Since the 1970s, the small molecule CMA has been considered a potent agent against viral infections, yet it was never approved for clinical use. Scientists at the Bonn University Hospital have now deciphered how the molecule can actually stimulate the immune system to combat viruses. The results are now being presented in the journal "EMBO" of the European Molecular Biology Organization. Finding an active substance to stimulate the immune system and thus better combat dangerous viruses has been ...

NASA's Hubble sees a Horsehead of a different color

2013-04-19
Astronomers have used NASA's Hubble Space Telescope to photograph the iconic Horsehead Nebula in a new, infrared light to mark the 23rd anniversary of the famous observatory's launch aboard the space shuttle Discovery on April 24, 1990. Looking like an apparition rising from whitecaps of interstellar foam, the iconic Horsehead Nebula has graced astronomy books ever since its discovery more than a century ago. The nebula is a favorite target for amateur and professional astronomers. It is shadowy in optical light. It appears transparent and ethereal when seen at infrared ...

Water-pipe smoking may not be a safe alternative to cigarette smoking

2013-04-19
PHILADELPHIA — Smoking tobacco in a water pipe resulted in a different pattern of exposure to toxic substances and may result in a cancer risk profile that is different from that of cigarette smoking, according to data published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research. "Water-pipe smoking at 'hookah bars' has become popular with young people in the United States, and some believe that it is less harmful than cigarette smoking," said Peyton Jacob III, Ph.D., a University of California, San Francisco research ...

Teen moms at greater risk for later obesity, U-M study finds

2013-04-19
ANN ARBOR, Mich. — A new study debunks the myth that younger moms are more likely to "bounce back" after having a baby – teenage pregnancy actually makes women more likely to become obese. Women who give birth as teens are significantly more likely to be overweight or obese later in life than women who were not teen moms, University of Michigan Health System researchers found. The nationally representative study, which is the first believed to identify teen pregnancy as a predictor of obesity, appears in the American Journal of Obstetrics & Gynecology. "When taking ...

Revolutionary new device joins world of smart electronics

2013-04-19
Smart electronics are taking the world by storm. From techno-textiles to transparent electronic displays, the world of intelligent technology is growing fast and a revolutionary new device has just been added to its ranks. Researchers at the University of Exeter have developed a new photoelectric device that is both flexible and transparent. The device, described in a paper in the journal ACS Nano, converts light into electrical signals by exploiting the unique properties of the recently discovered materials graphene and graphExeter. GraphExeter is the best known room temperature ...

Something's fishy in the tree of life

2013-04-19
NORMAN – Fishes account for over half of vertebrate species, but while groups such as mammals, birds and reptiles have been fairly well understood by scientists for decades, knowledge about relationships among many types of fishes was essentially unknown – until now. A team of scientists led by Richard Broughton, associate professor of biology in the College of Arts and Sciences at the University of Oklahoma, published two studies that dramatically increase understanding of fish evolution and their relationships. They integrated extensive genetic and physical information ...

Feinstein Institute Researcher provides insight into osteoarthritis

2013-04-19
MANHASSET, NY – A researcher at The Feinstein Institute for Medical Research has discovered additional mechanical properties of articular cartilage, a protective cartilage on the ends of bones that wears down over time, resulting in the development of osteoarthritis. The findings are published in the April issue of PLOS ONE. To better understand the onset and progression of osteoarthritis, Nadeen Chahine, PhD, and collaborators at other institutions looked at cells from articular cartilage using atomic force microscopy (AFM). They used this technology to measure the mechanical ...

LAST 30 PRESS RELEASES:

Recycling a pollutant to make ammonia production greener

Common institutional ownership linked to less aggressive business strategies in Chinese firms

Energy and regional factors drive carbon price volatility in China’s emissions trading markets

Researchers from NUS Medicine and the Institute of Mental Health detect early brain changes linked to future psychosis development

Cryopreserved vs liquid-stored platelets for the treatment of surgical bleeding

Cost-effectiveness of cryopreserved vs liquid-stored platelets for managing surgical bleeding

Adaptive Kalman filter boosts BDS-3 navigation accuracy in challenging environments

Home-based monitoring could transform care for patients receiving T-cell redirecting therapies

Listening to the 'whispers' of electrons and crystals: A quantum discovery

Report on academic exchange (colloquium) with Mapua University

Sport in middle childhood can breed respect for authority in adolescence

From novel therapies to first-in-human trials, City of Hope advances blood cancer care at the American Society of Hematology (ASH) annual conference

Research aims to strengthen the security of in-person voting machines

New study exposes hidden Alzheimer’s 'hot spots' in rural Maryland and what they reveal about America’s growing healthcare divide

ASH 2025: Study connects Agent Orange exposure to earlier and more severe cases of myelodysplastic syndrome

ASH 2025: New data highlights promise of pivekimab sunirine in two aggressive blood cancers ​

IADR elects George Belibasakis as vice-president

Expanding the search for quantum-ready 2D materials

White paper on leadership opportunities for AI to increase employee value released by University of Phoenix College of Doctoral Studies

ASH 2025: New combination approach aims to make CAR T more durable in lymphoma

‘Ready-made’ T-cell gene therapy tackles ‘incurable’ T-cell leukemia

How brain activity changes throughout the day

Australian scientists reveal new genetic risk for severe macular degeneration

GLP-1 receptor agonists likely have little or no effect on obesity-related cancer risk

Precision immunotherapy to improve sepsis outcomes

Insilico Medicine unveils winter edition of Pharma.AI, accelerating the path to pharmaceutical superintelligence

Study finds most people trust doctors more than AI but see its potential for cancer diagnosis

School reopening during COVID-19 pandemic associated with improvement in children’s mental health

Research alert: Old molecules show promise for fighting resistant strains of COVID-19 virus

Journal of Nuclear Medicine Technology supplement highlights advances in theranostics and opportunities for growth

[Press-News.org] Research harnesses solar-powered proteins to filter harmful antibiotics from water