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Pharmaceutical advances offer new options for health outcomes

2013-05-20
Orlando, FL (May 20, 2013) — Research presented at Digestive Disease Week® (DDW) explores pharmaceutical advances for treating irritable bowel syndrome with diarrhea (IBS-D) and hepatitis C. An international study holds promising results for patients suffering from IBS-D. In the phase II study, researchers found that the drug ibodutant significantly improved symptoms in more than 50 percent of the individuals treated. "While there's been a lot of progress in medicines for IBS with constipation, we haven't seen the same in IBS with diarrhea," said Jan Tack, MD, professor ...

Mayo Clinic: Inflammatory bowel disease raises risk of melanoma

2013-05-20
ROCHESTER, Minn. — Patients with inflammatory bowel disease (IBD) are at higher risk of melanoma, a form of skin cancer, report researchers at Mayo Clinic. Researchers found that IBD is associated with a 37 percent greater risk for the disease. The findings were presented at the Digestive Disease Week 2013 conference in Orlando, Fla. More than 1.5 million Americans have Crohn's disease or ulcerative colitis (UC), the most common forms of inflammatory bowel disease. Both conditions inflame the lining of the intestine, leading to bouts of watery diarrhea, rectal bleeding, ...

Team finds mechanism linking key inflammatory marker to cancer

2013-05-20
CHAMPAIGN, Ill. — In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth. Scientists call this Jekyll-and-Hyde molecule NF-kappa B. In healthy cells, it is a powerful "first responder," a vital part of the body's immune and inflammatory responses. It spends most of its life in the cell's cytoplasm, quietly awaiting orders. But when extracellular signals – of a viral or bacterial invasion, for example – set off chemical alarms, ...

New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More

2013-05-20
Boulder, Colo., USA – New Geology articles posted online ahead of print 9 and 16 May 2013 cover a wide swath of geoscience subdisciplines, including minerals exploration, archaeology, planetary geology, tectonics, oceanography, geophysics, and paleobotany. Locations studied include Siberia; the Sumatran subduction margin; the Monte Arsiccio mine at Alpi Apuane, Italy; Ukraine; Mars; and the Southeastern U.S. Atlantic Margin. Brief highlights follow: 1. Rubies, jadeite, and plate tectonics; 2. The clear fingerprint of ice ages left on coral reefs around the world; 3. ...

New GEOSPHERE science online covers Himalaya, Colorado River, McMurdo Sound, and more

2013-05-20
Boulder, Colo., USA – New Geosphere postings online on 7 and 16 May include additions to two special issues: CRevolution 2: Origin and Evolution of the Colorado River System II and The ANDRILL McMurdo Ice Shelf (MIS) and Southern McMurdo Sound (SMS) Drilling Projects. Other articles cover India-Asia collision; a Late Triassic snapshot in the U.S. Southwest; the Alabama and western Georgia Blue Ridge; and the Jemez Mountains volcanic field. Abstracts for these and other Geosphere papers are available at http://geosphere.gsapubs.org/. Representatives of the media may obtain ...

New study suggests candy consumption frequency not linked to obesity or heart disease

2013-05-20
WASHINGTON, D.C., May 20, 2013 – At a time when the spotlight is focused on obesity more than ever, new research suggests that frequency of candy consumption is not associated with weight or certain adverse health risks. According to a recent data analysis published in the April 30th issue of Nutrition Journal, adults who consume candy at least every other day are no more likely to be overweight nor have greater risk factors for cardiovascular disease (CVD) than moderate consumers (about once a week) or even less frequent candy eaters (less than 3 times per month).1 Almost ...

Disney researchers develop fast, economical method for high-definition video compositing

2013-05-20
ZURICH - Video compositing to create special effects, replace backgrounds or combine multiple takes of an actor's performance is an integral, but highly labor-intensive, part of modern film making. Researchers at Disney Research, Zürich, however, have found an innovative way to create these composite videos that is simple, fast, and easy to use. Rather than perform a painstaking segmentation of elements that are to be added or subtracted from a video, the Disney system, called DuctTake, uses computer algorithms to find a spatiotemporal "seam" through the video frame that ...

Robots learn to take a proper handoff by following digitized human examples

2013-05-20
A humanoid robot can receive an object handed to it by a person with something approaching natural, human-like motion thanks to a new method developed by scientists at Disney Research, Pittsburgh in a project partially funded by the International Center for Advanced Communication Technologies (interACT) at Carnegie Mellon University and Karlsruhe Institute of Technology (KIT). Recognizing that a person is handing something and predicting where the human plans to make the handoff is difficult for a robot, but the researchers from Disney and KIT solved the problem by using ...

Genetic screening could reveal hidden high risk for coronary heart disease

2013-05-20
The study comprised over 24,000 Finnish subjects and was led by Professor Samuli Ripatti. The results revealed that a panel of 28 genetic markers improved detection of individuals with high risk for coronary heart disease (CHD) (10-year risk ≥20%) over traditional risk factors. Identification of high-risk individuals is an important preventive strategy for CHD, because the current guidelines recommend statin treatment for the high-risk group. "The results indicate that genetic markers could be useful in CHD prevention, when used in addition to traditional risk factor ...

Study of young Israelis emphasizes need for avoidance of sun exposure

2013-05-20
Jerusalem, May 20, 2013 –A new study conducted using extensive medical records of over one million Israeli adolescents before military service shows clearly how exposure to the Israeli sun of young, light-skinned children increases substantially the risk of cutaneous melanoma (a serious form of skin cancer). The incidence of cutaneous melanoma is on the rise in all parts of the world where light-skinned people live. Rates have tripled over the last decades in the United States, and the rise was even steeper in Europe. What about in Israel? What segments of the population ...

Predicting infectious influenza

2013-05-20
A new computer model could help scientists predict when a particular strain of avian influenza might become infectious from bird to human, according to a report to be published in the International Journal Data Mining and Bioinformatics. Chuang Ma of the University of Arizona, Tucson, and colleagues at the Huazhong University of Science and Technology, Wuhan and the Wuhan Institute of Virology, explain that since 1997 several strains of avian influenza A virus (AIV), commonly known as "bird flu" have infected people directly from their natural bird hosts leading to numerous ...

Fossil brain teaser

2013-05-20
A new study conducted at the University of Bristol and published online today in the Journal of Evolutionary Biology sheds light on how the brain and inner ear developed in dinosaurs. Stephan Lautenschlager from Bristol's School of Earth Sciences, together with Tom Hübner from the Niedersächsische Landesmuseum in Hannover, Germany, picked the brains of 150 million year old dinosaurs. The two palaeontologists studied different fossils of the Jurassic dinosaur Dysalotosaurus lettowvorbecki: a very young (juvenile) individual of approximately three years of age and ...

Anabolic steroids may affect future mental health

2013-05-20
There is a link between use of anabolic-androgenic steroids and reduced mental health later in life. This is the main conclusion of a new study on elite male strength athletes that researchers from the University of Gothenburg recently published in the British Journal of Sports Medicine. Twenty per cent of the subjects in the study admitted steroid use. The study is published by CERA, which is the University of Gothenburg's centre for education and research on addiction. Together with colleagues from Sahlgrenska University Hospital, they found a connection between abuse ...

Germ-fighting vaccine system makes great strides in delivery

2013-05-20
SAN DIEGO (May 20, 2013) - A novel vaccine study from South Dakota State University (SDSU) will headline the groundbreaking research that will be unveiled at the American Association of Pharmaceutical Scientists' (AAPS) National Biotechnology Conference (NBC). The meeting takes place Monday, May 20 - Wednesday, May 22 at the Sheraton San Diego Hotel and Marina. "The main goal of a vaccine is to stimulate the immune system to fight against a pathogen that causes the disease", explained Dr. Hemachand Tummala, assistant professor of Pharmaceutical Sciences at SDSU. "We ...

Atherosclerotic disease heredity mapped in nationwide study

2013-05-20
Researchers at Lund University in Sweden have mapped the significance of heredity for common forms of atherosclerotic disease. No studies have previously examined whether different forms of the disease share heredity. The study looked at coronary heart disease, ischemic stroke, peripheral arterial disease and atherosclerosis of the aorta in individuals whose siblings and parents have suffered different types of cardiovascular disease. The results showed that heredity is highest for atherosclerosis of the aorta followed by peripheral arterial disease, coronary heart disease ...

Slow earthquakes: It's all in the rock mechanics

2013-05-20
Earthquakes that last minutes rather than seconds are a relatively recent discovery, according to an international team of seismologists. Researchers have been aware of these slow earthquakes, only for the past five to 10 years because of new tools and new observations, but these tools may explain the triggering of some normal earthquakes and could help in earthquake prediction. "New technology has shown us that faults do not just fail in a sudden earthquake or by stable creep," said Demian M. Saffer, professor of geoscience, Penn State. "We now know that earthquakes ...

First long-term study reveals link between childhood ADHD and obesity

2013-05-20
A new study conducted by researchers at the Child Study Center at NYU Langone Medical Center found men diagnosed as children with attention-deficit/hyperactivity disorder (ADHD) were twice as likely to be obese in a 33-year follow-up study compared to men who were not diagnosed with the condition. The study appears in the May 20 online edition of Pediatrics. "Few studies have focused on long-term outcomes for patients diagnosed with ADHD in childhood. In this study, we wanted to assess the health outcomes of children diagnosed with ADHD, focusing on obesity rates and ...

CosmosID unveils new tool for faster, specific and accurate testing of probiotics products

2013-05-20
Washington, D.C., May 20, 2013 –CosmosID®, a leading data mining solutions company for health and wellness, has reported as part of a collaboration results on analysis of labeling claims for the composition of probiotic products comparing speed, specificity, and accuracy. The Food and Drug Administration (FDA) and CosmosID® conducted side-by-side analysis of a number of commercially available probiotics, four of which have been reported at the American Society for Microbiology. The purpose of the tests was to compare the identity of species and strains present in the ...

Which women should be screened for high cholesterol?

2013-05-20
New Rochelle, NY, May 20, 2013—National guidelines recommend that at-risk women be screened for elevated cholesterol levels to reduce their chances of developing cardiovascular disease. But who is 'at risk?' The results of a study by investigators at the Centers for Disease Control and Prevention (CDC) to estimate the proportion of women young and old who have cholesterol levels that meet the definition of being at-risk are reported in an article in Journal of Women's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers. The article is available free ...

USF researchers find far-reaching, microvascular damage in uninjured side of brain after stroke

2013-05-20
Tampa, FL (May 20, 2013) -- While the effects of acute stroke have been widely studied, brain damage during the subacute phase of stroke has been a neglected area of research. Now, a new study by the University of South Florida reports that within a week of a stroke caused by a blood clot in one side of the brain, the opposite side of the brain shows signs of microvascular injury. Stroke is a leading cause of death and disability in the United States, and increases the risk for dementia. "Approximately 80 percent of strokes are ischemic strokes, in which the blood ...

Breakup of physician, drug company relationship could improve health care, cut cost

2013-05-20
PORTLAND, Ore. – A new report suggests that improved health care and significant reductions in drug costs might be attained by breaking up the age-old relationship between physicians and drug company representatives who promote the newest, more costly and often unnecessary prescription drugs. This system, which has been in place for decades, at one time benefitted doctors by keeping them up to date on new medications, and always provided generous amounts of "free" samples to get patients started on the newest drugs, as well as other supplies and gifts. But it's actually ...

New study finds blind people have the potential to use their 'inner bat' to locate objects

2013-05-20
New research from the University of Southampton has shown that blind and visually impaired people have the potential to use echolocation, similar to that used by bats and dolphins, to determine the location of an object. The study, which is published in the journal Hearing Research, examined how hearing, and particularly the hearing of echoes, could help blind people with spatial awareness and navigation. The study also examined the possible effects of hearing impairment and how to optimise echolocation ability in order to help improve the independence and quality of ...

Study supports 'aggressive' treatment for posterior fossa hematoma in newborns

2013-05-20
Philadelphia, Pa. (May 20, 2013) – Posterior fossa subdural hematoma (PFSDH) is a serious and rare condition in newborns, generally occurring after difficult deliveries. But with appropriate treatment, there's an excellent chance of good long-term outcomes even in severe cases of PFSDH, reports a study in the May issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. The results support an "aggressive" approach to evaluation and treatment—including surgery, ...

Penn research makes advance in nanotech gene sequencing technique

2013-05-20
The allure of personalized medicine has made new, more efficient ways of sequencing genes a top research priority. One promising technique involves reading DNA bases using changes in electrical current as they are threaded through a nanoscopic hole. Now, a team led by University of Pennsylvania physicists has used solid-state nanopores to differentiate single-stranded DNA molecules containing sequences of a single repeating base. The study was led by Marija Drndić, an associate professor in the Department of Physics and Astronomy in the School of Arts and Sciences, ...

Hospital emergency departments gaining in importance, study finds

2013-05-20
Hospital emergency departments play a growing role in the U.S. health care system, accounting for a rising proportion of hospital admissions and serving increasingly as an advanced diagnostic center for primary care physicians, according to a new RAND Corporation study. While often targeted as the most expensive place to get medical care, emergency rooms remain an important safety net for Americans who cannot get care elsewhere and may play a role in slowing the growth of health care costs, according to the study. Emergency departments are now responsible for about ...
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