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Study examines prevalence, characteristics of traumatic brain injuries among adolescents

2013-06-26
"Traumatic brain injury (TBI) among adolescents has been identified as an important health priority. However, studies of TBI among adolescents in large representative samples are lacking. This information is important to the planning and evaluation of injury prevention efforts, particularly because even minor TBI may have important adverse consequences," write Gabriela Ilie, Ph.D., of St. Michael's Hospital, Toronto, Canada, and colleagues, who examined the prevalence of TBI, mechanisms of injury, and adverse correlates in a large representative sample of adolescents living ...

Researchers strike gold with nanotech vaccine

2013-06-26
Scientists in the US have developed a novel vaccination method that uses tiny gold particles to mimic a virus and carry specific proteins to the body's specialist immune cells. The technique differs from the traditional approach of using dead or inactive viruses as a vaccine and was demonstrated in the lab using a specific protein that sits on the surface of the respiratory syncytial virus (RSV). The results have been published today, 26 June, in IOP Publishing's journal Nanotechnology by a team of researchers from Vanderbilt University. RSV is the leading viral cause ...

Death rates from heart disease continue to decline in most of the EU

2013-06-26
Death rates from heart disease in the European Union have more than halved in many countries since the early 1980s, according to new research published online today (Wednesday) in the European Heart Journal [1]. In the majority of countries, there have been ongoing steady reductions in heart disease death rates in both sexes and most age groups, including among younger people, despite increases in obesity and diabetes during this time. However, heart disease remains a leading cause of death in Europe. The authors of the study say their analysis shows little evidence ...

Study ranks social contacts by job and social group in bid to fight infectious diseases

2013-06-26
In the light of Novel Corona Virus, concerns over H7N9 Influenza in S.E. Asia, and more familiar infections such as measles and seasonal influenza, it is as important as ever to be able to predict and understand how infections transmit through the UK population. Researchers at the University of Warwick and University of Liverpool have mapped the daily contact networks of thousands of individuals to shed light on which groups may be at highest risk of contracting and spreading respiratory diseases. These scientists used an anonymous web and postal survey of 5,027 UK residents ...

Overweight causes heart failure -- large study with new method clarifies the association

2013-06-26
An international research team led by Swedish scientists has used a new method to investigate obesity and overweight as a cause of cardiovascular disease. Strong association have been found previously, but it has not been clear whether it was overweight as such that was the cause, or if the overweight was just a marker of another underlying cause, as clinical trials with long-term follow-ups are difficult to implement. A total of nearly 200,000 subjects were included in the researchers' study of the causality between obesity/overweight and diseases related to cardiovascular ...

Cutlery: Do size, weight, shape and color matter?

2013-06-26
The appearance of cutlery can affect perception of a food's taste, reports BioMed Central's open access journal Flavour. Food tastes saltier when eaten from a knife, and denser and more expensive from a light plastic spoon. Taste was also affected by the color of the cutlery. The crockery we use has been shown to alter our perception of food and drink. Beverages in cold colored glasses were rated more refreshing and the weight and color of a plate can alter how dense, salty or sweet food tastes. In this study, researchers from the University of Oxford demonstrated that ...

Study shows heart failure survivors at greater risk for cancer

2013-06-26
WASHINGTON (June 25, 2013) — Heart failure patients are surviving more often with the heart condition but they are increasingly more likely to be diagnosed with cancer, a trend that could be attributed to increased surveillance, side effects of treatments, or other causes, according to a study published online today in the Journal of the American College of Cardiology. "Heart failure patients are not only at an increased risk for developing cancer, but the occurrence of cancer increases mortality in these patients," explained Dr. Veronique Roger, MD, director of the Mayo ...

A deep brain disorder

2013-06-26
A group of investigators from San Diego State University's Brain Development Imaging Laboratory are shedding a new light on the effects of autism on the brain. The team has identified that connectivity between the thalamus, a deep brain structure crucial for sensory and motor functions, and the cerebral cortex, the brain's outer layer, is impaired in children with autism spectrum disorders (ASD). Led by Aarti Nair, a student in the SDSU/UCSD Joint Doctoral Program in Clinical Psychology, the study is the first of its kind, combining functional and anatomical magnetic ...

Symptoms of Prader-Willi syndrome associated with interference in circadian, metabolic genes

2013-06-26
(SACRAMENTO, Calif.) — Researchers with the UC Davis MIND Institute and Agilent Laboratories have found that Prader-Willi syndrome — a genetic disorder best known for causing an insatiable appetite that can lead to morbid obesity — is associated with the loss of non-coding RNAs, resulting in the dysregulation of circadian and metabolic genes, accelerated energy expenditure and metabolic differences during sleep. The research was led by Janine LaSalle, a professor in the UC Davis Department of Medical Microbiology and Immunology who is affiliated with the MIND Institute. ...

Laser guided codes advance single pixel terahertz imaging

2013-06-26
VIDEO: A new method for single pixel terahertz (THz) imaging developed by Boston College researchers uses a set of instructions delivered by a laser beam to tune THz waves in order... Click here for more information. CHESTNUT HILL, MA (June 25, 2013) – The universe is awash in terahertz (THz) waves, as harmless as they are abundant. But unlike other regions of the electromagnetic spectrum, THz has proven to be extremely difficult to manipulate in order to capture novel images ...

Blind(fold)ed by science: Study shows the strategy humans use to chase objects

2013-06-26
COLUMBUS, Ohio—A new study has found that chasing down a moving object is not only a matter of sight or of sound, but of mind. The study found that people who are blindfolded employ the same strategy to intercept a running ball carrier as people who can see, which suggests that multiple areas of the brain cooperate to accomplish the task. Regardless of whether they could see or not, the study participants seemed to aim ahead of the ball carrier's trajectory and then run to the spot where they expected him or her to be in the near future. Researchers call this a "constant ...

Immunohistochemistry effectively detects ALK rearrangement

2013-06-26
DENVER – ALK rearrangement has been demonstrated to be a potent oncogenic driver and a promising therapeutic target in non-small cell lung cancer (NSCLC). It defines a distinct molecular subset of NSCLC, in particular adenocarcinoma that can benefit by the treatment of ALK-inhibitors. Development of robust and reliable laboratory tests for predictive biomarkers is essential to select appropriate patients for targeted therapy. Researchers from the Chinese University of Hong King evaluated the practical usefulness of immunohistochemistry to detect ALK expression as a reliable ...

Continued research needed on treatment for women with lung cancer who are never smokers

2013-06-26
DENVER – The incidence of lung cancer in women affects an estimated 516,000 women worldwide, of which 100,000 are in the United States and 70,000 in Europe. Until now, lung cancers occurring in women have been treated similarly to lung cancers in men. However, numerous studies have highlighted different characteristics of lung cancer in women. Researchers at the University of Toulouse III in France aim to compare clinical, pathological and biological characteristics of lung cancer in cohorts of women smokers and women never-smokers. They looked at a total of 140 women, ...

PET-CT improves care of limited-stage small-cell lung cancer patients

2013-06-26
DENVER – Each year, 13 percent of all newly diagnosed lung cancer patients are diagnosed with small-cell lung cancer (SCLC). Approximately 39 percent of patients with SCLC are diagnosed with limited-stage disease, meaning the cancer is only present in one lung, but may have spread to lymph nodes or tissue between the lungs. These patients are often treated with chemotherapy and definitive radiation therapy. Staging information is essential because of the high propensity for metastatic disease in SCLC, and the identification of metastases can spare patients from the toxicity ...

Study details cancer-promoting mechanisms of overlooked components in secondhand smoke

2013-06-26
Tobacco smoke, diesel exhaust and oil combustion carry polycyclic aromatic hydrocarbons – PAHs that are known to cause cancer. But of these PAHs, the obviously dangerous high-molecular-weight PAHs like benzo[a]pyrene (BaP) have received the vast majority of research attention. Their low-molecular-weight cousins have been largely overlooked, in part because studies have shown that these compounds alone aren't very successful at mutating genes in cancer-causing ways. A University of Colorado Cancer Center study published in the journal PLoS One explores two of these low-molecular-weight ...

Vietnam vets with PTSD more than twice as likely to have heart disease

2013-06-26
Male twin Vietnam veterans with post-traumatic stress disorder (PTSD) were more than twice as likely as those without PTSD to develop heart disease during a 13-year period, according to a study supported by the National Institutes of Health. This is the first long-term study to measure the association between PTSD and heart disease using objective clinical diagnoses combined with cardiac imaging techniques. "This study provides further evidence that PTSD may affect physical health," said Gary H. Gibbons, M.D., director of the NIH's National Heart, Lung, and Blood ...

'Active surveillance' may miss aggressive prostate cancers in black men

2013-06-26
A Johns Hopkins study of more than 1,800 men ages 52 to 62 suggests that African-Americans diagnosed with very-low-risk prostate cancers are much more likely than white men to actually have aggressive disease that goes unrecognized with current diagnostic approaches. Although prior studies have found it safe to delay treatment and monitor some presumably slow-growing or low-risk prostate cancers, such "active surveillance" (AS) does not appear to be a good idea for black men, the study concludes. "This study offers the most conclusive evidence to date that broad application ...

Hiding in plain sight: New species of bird discovered in capital city

2013-06-26
A team of scientists with the Wildlife Conservation Society, BirdLife International, and other groups have discovered a new species of bird with distinct plumage and a loud call living not in some remote jungle, but in a capital city of 1.5 million people. Called the Cambodian tailorbird (Orthotomus chaktomuk), the previously undescribed species was found in Cambodia's urbanized capitol Phnom Penh and several other locations just outside of the city including a construction site. It is one of only two bird species found solely in Cambodia. The other, the Cambodian laughingthrush, ...

USC research IDs potential treatment for deadly, HIV-related blood cancer

2013-06-26
LOS ANGELES — Researchers at the USC Norris Comprehensive Cancer Center have discovered a promising new way to treat a rare and aggressive blood cancer most commonly found in people infected with HIV. The USC team shows that a class of drugs called BET bromodomain inhibitors effectively targets primary effusion lymphoma (PEL), a type of cancer for which those drugs were not expected to be effective. "It's a reversal of the paradigm," said Preet Chaudhary, MD, PhD, chief of the Nohl Division of Hematology and Blood Diseases at the Keck School of Medicine of USC and ...

Telecoupling pulls pieces of sustainability puzzle together

2013-06-26
Global sustainability is like a high-stakes jigsaw puzzle – and an international group of scientists have created a new framework to assemble the big picture without losing pieces. Scientists led by Jianguo "Jack" Liu, Michigan State University's Rachel Carson Chair in Sustainability, have built an integrated way to study a world that has become more connected – with faster and more socioeconomic and environmental interactions over distances. They say "telecoupling" describes how distance is shrinking and connections are strengthening between nature and humans. In Ecology ...

Human and canine lymphomas share molecular similarities, first large-scale comparison shows

2013-06-26
CHAPEL HILL, N.C. - Humans and their pet dogs are close, so close that they both develop a type of cancer called diffuse large B-cell lymphoma. In humans it's the most common lymphoma subtype while in dogs, it's one of the most common cancers in veterinary oncology. A team of scientists from the University of North Carolina School of Medicine, North Carolina State University's College of Veterinary Medicine and Duke University have conducted one of the first studies to directly compare canine and human B-cell lymphoma by examining molecular similarities and differences ...

New research finds flu shot effective regardless of circulating flu strain

2013-06-26
New research out of St. Michael's Hospital has found that despite popular belief, the flu shot is effective in preventing the flu, even if the virus going around does not match the vaccine. "It's quite common for people to say they are not going to get the flu shot this year because they've heard it does not match the strain of flu going around," said Dr. Andrea Tricco, the lead author of the paper and a scientist at the Li Ka Shing Knowledge Institute of St. Michael's Hospital. "However, we've found that individuals will be protected regardless of whether the flu strain ...

Delivering the best care to the right patient at the right time

2013-06-26
There are two popular models when it comes to delivering the best healthcare – using evidence-based guidelines or applying personalized medicine. Each method has its own merits and drawbacks, but according to one Northwestern Medicine® cardiologist, when the two theories are integrated the result is an optimal healthcare delivery model that is both less expensive and better for the patient. "It should not be one or the other but instead a combination of both," said Jeffrey Goldberger, MD, an attending cardiologist and cardiac electrophysiologist at Northwestern Memorial ...

Memory improves for older adults using computerized brain-fitness program

2013-06-26
FINDINGS: UCLA researchers have found that older adults who regularly used a brain-fitness program on a computer demonstrated significantly improved memory and language skills. The UCLA team studied 69 dementia-free participants, with an average age of 82, who were recruited from retirement communities in Southern California. The participants played a computerized brain-fitness program called Dakim BrainFitness, which trains individuals through more than 400 exercises in the areas of short- and long-term memory, language, visual-spatial processing, reasoning and ...

Hypertension-driven disease rapidly rising in sub-Saharan Africa

2013-06-26
NEW YORK (June 25, 2013) -- Based on the experience of a large hospital in Tanzania, Weill Cornell Medical College researchers have discovered a "startlingly" high burden of hypertension in this sub-Saharan African country. In the Journal of Hypertension, the researchers say non-communicable disease -- driven primarily by hypertension, resulting in stroke and other cardiovascular diseases -- accounted for nearly half of the deaths and admissions during a three-year period at Weill Bugando Medical Center, one of Tanzania's preeminent teaching hospitals. Previous research ...
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