Todd Doors are perhaps one of the most renowned door suppliers in the United Kingdom. They pride themselves on providing customers with an enviable range of interior and exterior doors and door furniture. But it's their attention to detail and their useful advice, which sets them above and beyond the rest. Their vast experience, spanning across a sixty-year period, has ensured they've become a trusted source for the very latest door styles and fashions: successfully mixing the traditional with the contemporary and unique. From sliding doors to white internal doors to ...

New Look is to launch a competition in the build-up to Christmas and it's another chance for bloggers to show how stylish they really are. The competition, Shape Up for Christmas, will celebrate five beautiful shapes identified by the modern woman. The five shapes: Pear-Shape, Straight Up & Down, Apple, Plus Size and Hour Glass give opportunity for a rich diversity of figures to show themselves in the best shimmering light. For style inspiration, entrants are offered the New Look Celebrity Shape Up Style Guide, with a much-loved and much-admired celebrity showcasing ...

In a recent study released by the Surdna Foundation, most North Americans are aware of the global climate changes brought on by extreme weather now happening across North America. The sad news is that the weather is getting worse according to the study. The proof proof is all around us - the recent tsunami, and Hurricane Sandy - the storm of the century, to name a few. And these changes are occurring more frequently! These effects of climate change have produced erratic weather behavior, which not only affects the environment but a person's skin, making it dry. And rain ...

Sarasota attorney Dennis Plews and his clients, a Bradenton woman and an Osprey man, are facing hundreds of thousands of dollars in sanctions and costs from the former Chief Circuit Judge in Sarasota. Judge Lee Haworth ruled that a lawsuit Plews filed against Jeffrey Luhrsen in 2009 was "grasping at air," and ordered Plews to personally pay Luhrsen's attorney's fees, which court papers indicate are about $300,000.00. Plews' clients, Jeanester Bryant and Jack LaRoe, must pay Luhrsen tens of thousands in costs, but they have even bigger problems. Both are facing ...

ControlCam announced today that in response to the recent FCC notice we have developed a new product geared towards Universities and Colleges to provide affordable CLI Flyover packages. ControlCam has been providing CLI Flyovers and Reports for over 20 years and serves most of the largest cable companies in the United States. In August of this year the FCC released a public notice to all Multichannel Video Programming Distributors (MVPD), both cable and non-cable, that they must monitor for and repair signal leakage if they are using the aeronautical band. These requirements ...

EE Technologies recently installed its 10th new surface mount technology line in its Empalme, Sonora manufacturing plant. The company manufactures in Mexico under The Offshore Group's Mexico Shelter Plan. This, along with installation of a Power Distribution Center (PDC) line, supports the manufacture of automotive products used globally. Many of EE Technologies' OEM and other customers are making decisions to bring products previously sent far offshore to North America, and increasingly to Mexico. The benefits of reshoring are significant for these customers. EE Technologies ...

Respiratory conditions that restrict breathing such as asthma and chronic obstructive pulmonary disease (COPD) are common killers worldwide. But no effective treatments exist to address the major cause of death in these conditions – excess mucus production. "There is good evidence that what kills people with severe COPD or asthma is mucus obstructing the airway," says Michael J. Holtzman, MD, the Selma and Herman Seldin Professor of Medicine at Washington University School of Medicine in St. Louis. "It's a huge unmet medical problem and is only increasing in this country ...

The number of prescription drugs that can have serious adverse effects from interactions with grapefruit are markedly increasing, yet many physicians may be unaware of these effects, states an article published in CMAJ (Canadian Medical Association Journal). The article, a review by the researchers who discovered the interactions more than 20 years ago, summarizes evidence to help clinicians better understand the serious effects this common food can have when consumed with certain prescription drugs. "Many of the drugs that interact with grapefruit are highly prescribed ...

Rates of hemorrhage for older patients on warfarin therapy are much higher than rates reported in clinical trials, found a study published in CMAJ (Canadian Medical Association Journal). "The rate of hemorrhage in our study is considerably higher than those reported in randomized controlled trials of warfarin therapy, which have ranged between 1% and 3% per person-year," writes lead author Tara Gomes, Institute for Clinical Evaluative Sciences (ICES), Toronto, with coauthors. Warfarin, a commonly used blood thinner, is used to treat patients with atrial fibrillation ...

In a commentary to be published in the Dec. 12 issue of The Journal of the American Medical Association, two Johns Hopkins faculty members predict an ever-diminishing role for government and drug company funding of basic biomedical research and suggest scientists look to "innovative" kinds of private investment for future resources. Current negotiations in Washington over sequestration and the so-called "fiscal cliff" provide an opportunity to fundamentally rethink the funding of biomedical research, they say. Pointing to a decade of flat government funding for biomedical ...

Antifibrinolytic drugs are frequently used to prevent blood loss during surgery, but sometimes cause convulsive seizures. In this issue of the Journal of Clinical Investigation, researchers led by Beverly Orser at the University of Toronto investigated the molecular mechanisms that underlie this side effect. By studying antifibrinolytics in mice, Orser and colleagues found that the drugs inhibited the activity of glycine receptors in the brain, leading to seizures. Seizures could be prevented by co-treatment with the general anesthetic isoflurane. This study explains the ...

Obesity is associated with insulin resistance and type 2 diabetes, both of which can be significantly improved by weight loss. Gastric bypass and adjustable gastric banding are two bariatric surgery techniques that are frequently used to effect weight loss in obese patients, but it is unclear if the two procedures produce different outcomes. In this issue of the Journal of Clinical Investigation, researchers led by Samuel Klein at the University of Washington School of Medicine in St. Louis compared the effects of 20% weight loss induced by either gastric bypass or adjustable ...

Bariatric surgery procedures have similar therapeutic benefits in obese adults Obesity is associated with insulin resistance and type 2 diabetes, both of which can be significantly improved by weight loss. Gastric bypass and adjustable gastric banding are two bariatric surgery techniques that are frequently used to effect weight loss in obese patients, but it is unclear if the two procedures produce different outcomes. In this issue of the Journal of Clinical Investigation, researchers led by Samuel Klein at the University of Washington School of Medicine in St. Louis ...

ANN ARBOR—It's a sad but familiar scene near the grounds of many medical campuses: hospital-gowned patients, some toting rolling IV poles, huddled in clumps under bus shelters or warming areas, smoking cigarettes. Smoking causes 30 percent of all cancer deaths and 87 percent of all lung cancer deaths. Yet, roughly 50 percent to 83 percent of cancer patients keep smoking after a cancer diagnosis, through treatment and beyond, says Sonia Duffy, University of Michigan School of Nursing researcher. For patients who quit on their own, relapse rates (as in the general population) ...

When faced with scandal or wrongdoing, corporations should stick to the facts in their post-crisis messaging, according to a new study from researchers at Rice University, the University of Georgia and the University of Maryland – College Park. The study, "Managing the message: The effects of firm actions and industry spillovers on media coverage following wrongdoing," examined quarterly media coverage of 45 U.S. public toy companies a 10-year period and over 5,500 press releases generated by the companies during that time. Almost half of the companies surveyed conducted ...

Some people live their lives by the motto "no risk - no fun!" and avoid hardly any risks. Others are clearly more cautious and focus primarily on safety when investing and for other business activities. Scientists from the University of Bonn in cooperation with colleagues from the University of Zurich studied the attitudes towards risk in a group of 56 subjects. They found that in people who preferred safety, certain regions of the brain show a higher level of activation when they are confronted with quite unforeseeable situations. In addition, they do not distinguish as ...

AUGUSTA, Ga. – The first evidence of blood vessel dysfunction has been found in a small cohort of generally healthy young people with cystic fibrosis, researchers report. "Even though the lung function in these kids is fine at this point, there is evidence of vascular dysfunction and exercise intolerance," said Dr. Ryan A. Harris, clinical exercise physiologist at the Medical College of Georgia and Institute of Public and Preventive Health at Georgia Health Sciences University. "We think this blood vessel dysfunction could be contributing to their exercise intolerance, ...

It all started with a crab apple tree. Two years ago, a 71-year-old Indiana man impaled his hand on a branch after cutting down a dead tree. The wound caused an infection that led scientists to discover a new bacterium and solve a mystery about how bacteria came to live inside insects. On Oct. 15, 2010, Thomas Fritz, a retired inventor, engineer and volunteer firefighter, cut down a dead, 10-foot-tall crab apple tree outside his home near Evansville, Ind. As he dragged away the debris, he got tangled in it and fell. A small branch impaled his right hand in the fleshy ...

Visualize a dusty place where stream beds are sand and lakes are flats of dried mud. Are we on Mars? In fact, we're on arid parts of Earth, a planet where water covers some 70 percent of the surface. How long will water be readily available to nourish life here? Scientists funded by the National Science Foundation's (NSF) Dynamics of Coupled Natural and Human Systems (CNH) program are finding new answers. NSF-supported CNH researchers will address water resources management and policy in a changing world at the fall meeting of the American Geophysical Union (AGU), ...

MANHATTAN, Kan. -- The key to motivation in physical activity may be feeling inadequate. One Kansas State University researcher found that those who exercised with a teammate whom they perceived to be better increased their workout time and intensity by as much as 200 percent. Brandon Irwin, assistant professor of kinesiology, was the principle investigator in a study that tested whether individuals engage in more intense physical activity when alone, with a virtual partner or competing against a teammate. "People like to exercise with others and make it a social activity," ...

CAMBRIDGE, Mass. — The quest to harness a broader spectrum of sunlight's energy to produce electricity has taken a radically new turn, with the proposal of a "solar energy funnel" that takes advantage of materials under elastic strain. "We're trying to use elastic strains to produce unprecedented properties," says Ju Li, an MIT professor and corresponding author of a paper describing the new solar-funnel concept that was published this week in the journal Nature Photonics. In this case, the "funnel" is a metaphor: Electrons and their counterparts, holes — which are ...

An insect growth regulator is one of the latest technologies U.S. Department of Agriculture (USDA) scientists are adding to their arsenal to help fight house flies that spread bacteria to food. Agricultural Research Service (ARS) scientists at the agency's Center for Medical, Agricultural, and Veterinary Entomology in Gainesville, Fla., are using an insect growth regulator called pyriproxyfen to kill house flies that spread bacteria that can cause diarrhea and other illnesses. When pyriproxyfen is applied to larval breeding sites such as manure, it mimics a hormone in ...

New combinations of medical imaging technologies hold promise for improved early disease screening, cancer staging, therapeutic assessment, and other aspects of personalized medicine, according to Ge Wang, director of Virginia Tech's Center for Biomedical Imaging, in a recent paper that appeared in the refereed journal PLOS ONE. The integration of multiple major tomographic scanners into a single framework "is a new way of thinking in the biomedical imaging world" and is evolving into a "grand fusion" of many imaging modalities known as "omni-tomography," explained Wang, ...

Durham, NC – The question of how life began on a molecular level has been a longstanding problem in science. However, recent mathematical research sheds light on a possible mechanism by which life may have gotten a foothold in the chemical soup that existed on the early Earth. Researchers have proposed several competing theories for how life on Earth could have gotten its start, even before the first genes or living cells came to be. Despite differences between various proposed scenarios, one theme they all have in common is a network of molecules that have the ability ...

Like a homeowner prepping for a hurricane, the bacterium Bacillus subtilis uses a long checklist to prepare for survival in hard times. In a new study, scientists at Rice University and the University of Houston uncovered an elaborate mechanism that allows B. subtilis to begin preparing for survival, even as it delays the ultimate decision of whether to "hunker down" and withdraw into a hardened spore. The new study by computational biologists at Rice and experimental biologists at the University of Houston is available online in the Proceedings of the National Academy ...