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'Synthetic lethality' strategy improves molecularly targeted cancer therapy

2010-09-22
PHILADELPHIA (September 21, 2010)—Molecularly targeted therapies can reduce tumors rapidly. However, not all tumors respond to the drugs, and even those that do often develop resistance over time. Looking for a way to combat the problem of resistance, researchers at Fox Chase Cancer Center hypothesized that hitting already weakened cancer cells with a second targeted agent could kill them—but only if it was the right second agent. One well-validated molecular target for anti-cancer drugs is the epidermal growth factor receptor, or EGFR. Using a novel screening approach, ...

Results of the placement of multiple endoscopic stents for postoperative biliary strictures remains excellent after long-term follow-up

2010-09-22
OAK BROOK, Ill. – September 21, 2010 – Researchers from Italy have reported results from more than 10 years of follow-up showing that the placement of multiple endoscopic stents for the treatment of postoperative biliary strictures remains excellent with a low rate of stricture recurrence after this lengthy period of time. When strictures do recur, they can be safely and successfully retreated endoscopically. The study appears in the September issue of GIE: Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal ...

Queen's University researchers locate impulse control center in brain

2010-09-22
Impulsive behaviour can be improved with training and the improvement is marked by specific brain changes, according to a new Queen's University study. A research team led by neuroscience PhD student Scott Hayton has pinpointed the area of the brain that controls impulsive behavior and the mechanisms that affect how impulsive behavior is learned. The findings could have a significant impact on the diagnosis and treatment of several disorders and addictions, including ADHD and alcoholism. "In the classroom, kids often blurt out answers before they raise their hand. ...

GOES-11 catches quick birth of Tropical Storm Georgette already moving into Baja California

GOES-11 catches quick birth of Tropical Storm Georgette already moving into Baja California
2010-09-22
Tropical Storm Georgette formed pretty quickly and the GOES-11 satellite captured her clouds extending over extreme southern Baja California and western Mexico today. Georgette formed just south of Cabo San Lucas this morning and is headed for a Baja landfall. The Geostationary Operational Environmental Satellite or GOES-11 is stationary in its position in space, watching over the weather in the western U.S. GOES-11 captured an infrared image of Tropical Storm Georgette's rounded cloud cover stretching north into Baja California, Mexico at 13:15 UTC 9:15 a.m. EDT today, ...

NASA infrared imagery sees tropical depression 14 becomes 12th tropical storm: Lisa

NASA infrared imagery sees tropical depression 14 becomes 12th tropical storm: Lisa
2010-09-22
This Atlantic hurricane season has now spawned 14 tropical depressions and 12 of them have strengthened into tropical storms. The latest is now called Tropical Storm Lisa and is in the Eastern Atlantic Ocean. NASA's Aqua satellite flew over Lisa when she was still a low pressure area, but showed a center of circulation and banding of thunderstorms circling it, indicating the storm was getting organized. The Atmospheric Infrared Sounder (AIRS) instrument that flies aboard NASA's Aqua satellite captured "Lisa" when she was still a low pressure area yesterday, Sept. 20 at ...

Hurricane watches up in Canada as the GOES-13 Satellite sees Hurricane Igor still expanding

Hurricane watches up in Canada as the GOES-13 Satellite sees Hurricane Igor still expanding
2010-09-22
Hurricane Igor may be changing into an extra tropical storm and losing his warm core of energy, but he hasn't lost his punch as hurricane watches are up today in eastern Canada. The GOES-13 satellite captured a look at Hurricane Igor this morning, and noticed the storm continues to grow larger and part of that expansion is likely a result of absorbing Julia's remnants. The Geostationary Operational Environmental Satellite or GOES-13 is stationary in its position in space, watching over the weather in the eastern U.S. GOES-13 captured a visible satellite image of Hurricane ...

High-dose aspirin reduces pain for severe headache and migraine

2010-09-22
An inexpensive, hundred-year-old therapy for pain – aspirin – is effective in high doses for the treatment of severe headache and migraine caused by drug withdrawal, according to a new study by researchers with the UCSF Headache Center. Study participants were administered aspirin through an IV and 25 percent of the time they reported a significant reduction in pain – three points on the 10-point pain scale. (A difference of three points downgrades a headache from severe to moderate, moderate to mild, or from mild to pain-free). Participants reported a more modest pain ...

Research shows child rearing practices of distant ancestors foster morality, compassion in kids

2010-09-22
Ever meet a kindergartener who seemed naturally compassionate and cared about others' feelings? Who was cooperative and didn't demand his own way? Chances are, his parents held, carried and cuddled him a lot; he most likely was breastfed; he probably routinely slept with his parents; and he likely was encouraged to play outdoors with other children, according to new research findings from the University of Notre Dame. Three new studies led by Notre Dame Psychology Professor Darcia Narvaez show a relationship between child rearing practices common in foraging hunter-gatherer ...

Scientists using lasers to cool and control molecules

2010-09-22
New Haven, Conn.—Ever since audiences heard Goldfinger utter the famous line, "No, Mr. Bond; I expect you to die," as a laser beam inched its way toward James Bond and threatened to cut him in half, lasers have been thought of as white-hot beams of intensely focused energy capable of burning through anything in their path. Now a team of Yale physicists has used lasers for a completely different purpose, employing them to cool molecules down to temperatures near what's known as absolute zero, about -460 degrees Fahrenheit. Their new method for laser cooling, described ...

Doctor's health habits affect patient counseling

2010-09-22
ANN ARBOR, Mich. -- Physician's confidence in their abilities to counsel patients on a healthy diet and exercise may be related to their own personal habits, according to a study by the University of Michigan Cardiovascular Center. Confidence in counseling depended on a doctor's own exercise time, being overweight, and if the doctor had adequate training in talking to patients about diet and exercise. The study, published online ahead of print Oct. 1 in Preventive Cardiology, shows doctors' own health habits matter when it comes to patient counseling. "Living a healthy ...

Neanderthals more advanced than previously thought

2010-09-22
Denver (September 21, 2010) – For decades scientists believed Neanderthals developed `modern' tools and ornaments solely through contact with Homo sapiens, but new research from the University of Colorado Denver now shows these sturdy ancients could adapt, innovate and evolve technology on their own. The findings by anthropologist Julien Riel-Salvatore challenge a half-century of conventional wisdom maintaining that Neanderthals were thick-skulled, primitive `cavemen' overrun and outcompeted by more advanced modern humans arriving in Europe from Africa. "Basically, ...

Study offers first explanation of how cells rapidly repair and maintain structure

2010-09-22
SALT LAKE CITY—Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have discovered that a protein, zyxin, is necessary for the maintenance and repair of the cell's cytoskeleton, or internal framework, which serves as the muscle and bone of the cell. The research has implications for cancer, as well as other diseases, since alterations in the cytoskeleton are often associated with disease. The research was published in the Sep. 14, 2010, issue of the journal Developmental Cell. "Just like people, the cells in our bodies are exposed to all kinds of ...

Freshman weight gain: Women with heavy roommates gain less

2010-09-22
ANN ARBOR, Mich.---A new University of Michigan study finds that college women with roommates who weigh more than average gain less weight during their freshman year than women with slimmer roommates: half a pound versus 2.5 pounds. That compares to the typical freshman weight gain of 2.5-to-6 pounds---much less than the mythical "Freshman 15." "This finding seems counterintuitive, but there are some good explanations for why it may be happening," said Kandice Kapinos, an assistant research scientist at the U-M Institute for Social Research. According to Kapinos, ...

BookWhirl.com Features Dr. Sarah M. Levy and Al Andalus - A Trail of Discoveries by Michael Misfud

2010-09-22
BookWhirl.com's featured book and author for the month of September is about spiritual reflections and cultural discoveries. The featured book is Al Andalus - A Trail of Discoveries by Michael Misfud, and the featured author is Episcopal priest, Dr. Sandra M. Levy. Al Andalus - A Trail of Discoveries is a book about the last anarchists of Europe. It's a book where readers can follow through and learn the significance of a people who have been misunderstood because of their intransigence and passion. Al Andalus - A Trail of Discoveries includes interesting facts and information ...

NewsWorthy?!STL Cyber Cafe & Copy Center Opens in the Fox Park Neighborhood

2010-09-22
Having a nice relaxing atmosphere to work or study in is hard to come by, but at NewsWorthy?!STL that is exactly what you will find. This Cyber Cafe sits right in the heart of the Fox Park Neighborhood in South St. Louis and offers services such as Wi-Fi, and desktop internet access. The cafe also provided the neighborhood with a full service business center to make copies and other services such as sending and receiving faxes, and cd duplication. The cafe also features beverages, snacks and printing services such as flyers, posters, and custom t-shirt designing. Newsworthy?!STL ...

Professional Fire Protection Engineer Creates Alarm Arm No Ladder Smoke Alarm That Increases Fire Protection and Makes Smoke Alarm Installation and Replacing Batteries Safe.

2010-09-22
The Alarm Arm provides many advantages over ladders. The design allows for a quick and easy installation of smoke alarms while standing on the floor and can even be used while sitting in a wheelchair. No more dangerous falls off ladders, no more cumbersome ladders to drag around the house, and no mess to clean up. With the Alarm Arm, installing smoke alarms takes minutes, and changing batteries takes seconds. "I installed a smoke alarm using the Alarm Arm in five minutes while standing," says John Williams. Williams has a neuromuscular disorder and has difficulty using ...

The Parents Handbook To Give Away 4 American Airlines Tickets To Vail, Colorado

2010-09-22
The Parents Handbook is giving its readers and viewers the opportunity to register for a chance to win 4 free tickets on American Airlines. The round trip tickets will be valid for travel to/from the Vail - Eagle County Regional Airport (EGE) from/to any domestic US 48 American Airlines destination. Vail and the Vail Valley are in the heart of the Colorado Rockies and offer a wealth of indoor and outdoor activities for the entire family. Winter destinations include world class skiing and snowboarding at Vail Mountain and Beaver Creek. Both are around 30 minutes from ...

Gartner VP, Jeffrey Mann, Joins Open-Xchange Partner Summit Lineup

2010-09-22
Open-Xchange, a provider of business-class open source collaboration software, today announced its second Open-Xchange Partner Summit will take place on November 4 in Cologne, Germany at KölnSky. The Summit provides the partner community with a forum to learn how to advance their business with e-mail and collaboration services. "Mega-trends in Cloud Computing, Software-as-a-Service (SaaS) and Mobility" will top the agenda at the Partner conference. Together with Summit sponsors, eleven, eZuce, IPBrick, LuxCloud, LWsystems, MESH, MicroDoc, Parallels, Sachsen DV, Scality, ...

AFFORDABLESEOFL.COM provides SEO and Web Marketing services for Tampa Bay businesses

2010-09-22
Does your Tampa firm / practice need a marketing push? With so much competition out there, it's no wonder why Tampa small, medium size businesses and large enterprises have increased their marketing efforts, and gone online to get the biggest return for their dollar! The Tampa SEO company, AffordableSEOFL.com has built a cutting-edge technology for various businesses in Tampa bay area to increase their online visibility with the proven search engine optimization (SEO) techniques customized to their individual requirements. Utilizing superior internet marketing tools ...

Leading Tarp And Canopy Supplier Announces Launch of a New Online Store.

2010-09-22
Bullseye Specialty Shops Inc, a leading supplier and distributor of canopy tents and poly tarp products, has announced the purchase and launch of their re-designed website titled Tents-Canopy.com. Although the website has been servicing the public since 2004, executives state that this newly re-designed website will offer more products and 24 hour customer support. Bullseye Specialty Shops is no stranger to the outdoor shelter industry and has had much success with another tarp related website titled CanopiesAndTarps.com. Specializing in a range of outdoor shelter products ...

Axceler Ships Davinci Migrator for SharePoint 2010

2010-09-22
- Axceler, the leader in administration and migration software for Microsoft SharePoint, today announced the immediate availability of Davinci Migrator for SharePoint 2010, the first new product to be introduced as a result of its acquisition of echoTechnology. Davinci Migrator for SharePoint 2010 offers comprehensive, risk-based control when moving to the latest SharePoint platform. Davinci Migrator for SharePoint 2010 is available now from Axceler on Axceler.com. Davinci Migrator reduces the risks, lowers the overall cost and shortens the time it takes to complete ...

The Preiss Company's Donna Preiss Keynotes Triangle Ladies Power Lunch

2010-09-22
Donna Preiss, Founder and CEO of The Preiss Company, recently served as the keynote speaker for the Triangle Ladies Power Lunch. The two-hour event, held on August 18th at the Sheraton Imperial in Raleigh, provided Preiss the opportunity to share her personal story with luncheon attendees. The Triangle Power Lunch is dedicated to showcasing successful women in the triangle. Each month, the event's keynote speaker is a woman from the Triangle area who has blazed her own trail and found great success along the way. To add to this unique event, there is also an hour of ...

Trig Web Design moves to Raleigh NC

2010-09-22
Trig Web Design has moved to Raleigh, North Carolina, which has considerably less overhead to support their continued growth, and will help keep their web design and Internet marketing prices competitive for their clients. "We are very excited to bring our outstanding web services to the businesses of Raleigh, while still being able to service our existing clients nationwide" said Charlie Trig, CEO and chief web developer at Trig Web Design, Inc. "We realized that the Tampa bay area simply did not give us the same opportunities Raleigh does, both economically and socially." Originally ...

aViewFromtheEdge.net Launches Contest to Find the Next Activist Photographer

2010-09-22
Nicole Longstreath of aViewFromTheEdge.net has announced the start of a new contest -"Think You Can Shoot?" - to find the newest activist photographer in the world. The winner will receive a featured gallery on the newly redesigned aViewFromTheEdge.net website, including commission on their sales. The featured photographer will have the opportunity to share their views on current, socially relevant topics with the AViewFromTheEdge.net audience. In addition to this exciting contest, AViewFromTheEdge.net will be hosting a gala event on September 25, 2010. "Fabric of Freedom" ...

Platinum Law Group: Benefits of Bankruptcy Featuring Platinum Law Group

2010-09-22
Platinum Law Group: Benefits of Bankruptcy Featuring Platinum Law Group According to Platinum Law Group, bankruptcy is basically a state of a person or a firm unable to pay off the debts. In legal terms, bankruptcy refers to the settlement of liabilities of a person/organization, fully or in parts, who are in a state of not able to meet the incurred financial obligations. The purpose of such a settlement is to uniformly distribute the bankrupt's assets equitably among the creditors, and, to relieve the debtor from further liability, in most cases. Platinum Law Group ...
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