(Press-News.org) Androgen deprivation therapy is a common and effective treatment for advanced prostate cancer. However, among other side-effects, it can cause significant bone thinning in men on long-term treatment. A new study¹ by Vahakn Shahinian and Yong-Fang Kuo from the Universities of Michigan and Texas respectively, finds that although bone mineral density testing is carried out on some men receiving this therapy, it is not routine. They did note, however, that men were significantly more likely to be tested when they were being cared for by both a urologist and a primary care physician. Their paper² appears in the Journal of General Internal Medicine, published by Springer.
Androgen deprivation therapy cuts off the production of testosterone by the male testes. This prolongs the life of men with advanced prostate cancer, often by years. However, the therapy can cause osteoporosis which carries an increased risk of fracture. There are treatments available which can help reduce the extent of osteoporosis suffered. Despite recommendations for bone mineral density testing being incorporated into practice guidelines in 2002, it still does not seem to be carried out frequently enough.
In order to ascertain current levels of testing, the researchers looked at the medical records of over 80,000 men with prostate cancer in a Medicare claims database between 1996 and 2008. Although they noted that the levels of bone mineral density testing had increased over those years, only just over 11 percent of men received a test for osteoporosis in the last year studied.
According to the authors, "The absolute rates of bone mineral density testing remain low, but are higher in men who have a primary care physician involved in their care." Levels of testing were lowest in men being cared for by just a urologist alone.
The authors emphasize that bone care is not within the usual remit of most urologists and, as such, may be outside their comfort zone for diagnosis and management. Urologists are not alone in this, though, as breast and colorectal cancer patients also tend to fare better with the involvement of a primary care physician in addition to their oncologist.
It would therefore appear important to derive a system whereby primary care physicians remain involved in the care of men with prostate cancer. In addition, urologists need to be made more aware of the risk to bones and men starting androgen deprivation therapy need to know to ask about the test.
###
References
1. Shahinian VB and Kuo YF (2013). Patterns of bone mineral density testing in men receiving androgen deprivation for prostate cancer. Journal of General Internal Medicine DOI: 10.1007/s11606-013-2477-2
2. This work was supported by grants from the National Cancer Institute and the American Cancer Society.
The full-text article is available to journalists on request.
Primary care physicians vital to complete care of prostate cancer patients
Men receiving androgen deprivation therapy need to be aware of effects it can have on their bones
2013-05-14
ELSE PRESS RELEASES FROM THIS DATE:
Scientists find extensive glacial retreat in Mount Everest region
2013-05-14
Cancún, Mexico -- Researchers taking a new look at the snow
and ice covering Mount Everest and the national park that
surrounds it are finding abundant evidence that the world's tallest
peak is shedding its frozen cloak. The scientists have also been
studying temperature and precipitation trends in the area and
found that the Everest region has been warming while snowfall
has been declining since the early 1990s.
Members of the team conducting these studies will present their
findings on May 14 at the Meeting of the Americas in Cancun,
Mexico - a scientific ...
New program successful in reducing service and substance use among frequent health care users
2013-05-14
TORONTO, May 14, 2013—A program co-led by St. Michael's Hospital could be the next widely used model to treat patients who are frequent users of the health care system and have severe addictions, often complicated by homelessness and mental health problems.
The Toronto Community Addiction Team (TCAT) was developed to improve health and social outcomes for people with addictions who are frequent users of health services by providing one-on-one intensive case management from a harm reduction approach. The team works with clients to provide services such as individual therapy, ...
First precise MEMS output measurement technique unveiled
2013-05-14
Tuesday 14th May, Washington DC - The commercial application of MEMS, or micro-electro-mechanical systems, will receive a major boost today following the presentation of a brand new way to accurately measure the power requirements and outputs of all existing and future devices. The cheap and easy to apply technique will be presented for the first time today at the TechConnect World Conference 2013 by a research team from Laboratoire national de métrologie et d'essais (LNE) in France. The researchers believe it will help manufacturers improve product performance, develop ...
Wayne State researcher's technique helps robotic vehicles find their way
2013-05-14
DETROIT — A Wayne State University researcher understands that the three most important things about real estate also apply to small ground robotic vehicles: location, location, location.
In a paper recently published in the journal IEEE Transactions on Parallel and Distributed Systems, Weisong Shi, Ph.D., associate professor of computer science in the College of Engineering, describes his development of a technique called LOBOT that provides accurate, real-time, 3-D positions in both indoor and outdoor environments. The project was supported in part by the Wayne State ...
Alzheimer's markers predict start of mental decline
2013-05-14
Scientists at Washington University School of Medicine in St. Louis have helped identify many of the biomarkers for Alzheimer's disease that could potentially predict which patients will develop the disorder later in life. Now, studying spinal fluid samples and health data from 201 research participants at the Charles F. and Joanne Knight Alzheimer's Disease Research Center, the researchers have shown the markers are accurate predictors of Alzheimer's years before symptoms develop.
"We wanted to see if one marker was better than the other in predicting which of our participants ...
Engineered biomaterial could improve success of medical implants
2013-05-14
It's a familiar scenario – a patient receives a medical implant and days later, the body attacks the artificial valve or device, causing complications to an already compromised system.
Expensive, state-of-the-art medical devices and surgeries often are thwarted by the body's natural response to attack something in the tissue that appears foreign. Now, University of Washington engineers have demonstrated in mice a way to prevent this sort of response. Their findings were published online this week in the journal Nature Biotechnology.
The UW researchers created a synthetic ...
Pitt chemists demonstrate nanoscale alloys so bright they could have potential medical applications
2013-05-14
PITTSBURGH—Alloys like bronze and steel have been transformational for centuries, yielding top-of-the-line machines necessary for industry. As scientists move toward nanotechnology, however, the focus has shifted toward creating alloys at the nanometer scale—producing materials with properties unlike their predecessors.
Now, research at the University of Pittsburgh demonstrates that nanometer-scale alloys possess the ability to emit light so bright they could have potential applications in medicine. The findings have been published in the Journal of the American Chemical ...
Human disease leptospirosis identified in new species, the banded mongoose, in Africa
2013-05-14
The newest public health threat in Africa, scientists have found, is coming from a previously unknown source: the banded mongoose.
Leptospirosis, the disease is called. And the banded mongoose carries it.
Leptospirosis is the world's most common illness transmitted to humans by animals. It's a two-phase disease that begins with flu-like symptoms. If untreated, it can cause meningitis, liver damage, pulmonary hemorrhage, renal failure and death.
"The problem in Botswana and much of Africa is that leptospirosis may remain unidentified in animal populations but contribute ...
Mining the botulinum genome
2013-05-14
The toxin that causes botulism is the most potent that we know of. Eating an amount of toxin just 1000th the weight of a grain of salt can be fatal, which is why so much effort has been put into keeping Clostridium botulinum, which produces the toxin, out of our food.
The Institute of Food Research on the Norwich Research Park has been part of that effort through studying the bacteria and the way they survive, multiply and cause such harm. In new research, IFR scientists have been mining the genome of C. botulinum to uncover new information about the toxin genes.
There ...
Studies support population-based efforts to lower excessive dietary sodium intakes
2013-05-14
WASHINGTON -- Recent studies that examine links between sodium consumption and health outcomes support recommendations to lower sodium intake from the very high levels some Americans consume now, but evidence from these studies does not support reduction in sodium intake to below 2,300 mg per day, says a new report from the Institute of Medicine.
Despite efforts over the past several decades to reduce dietary intake of sodium, a main component of table salt, the average American adult still consumes 3,400 mg or more of sodium a day – equivalent to about 1 ½ teaspoons ...
LAST 30 PRESS RELEASES:
Much-needed new drug approved for deadliest blood cancer
American College of Lifestyle Medicine publishes official position on lifestyle medicine as a framework for delivery of high-value, whole-person care
Hospital infections associated with higher risk of dementia
Thyroid dysfunction during pregnancy may increase autism risk in children
Cross-national willingness to share
Seeing rich people increases support for wealth redistribution
How personalized algorithms lead to a distorted view of reality
Most older drivers aren’t thinking about the road ahead, poll suggests
Earthquakes shake up Yellowstone’s subterranean ecosystems
Pusan National University study reveals a shared responsibility of both humans and AI in AI-caused harm
Nagoya Institute of Technology researchers propose novel BaTiO3-based catalyst for oxidative coupling of methane
AI detects first imaging biomarker of chronic stress
Shape of your behind may signal diabetes
Scientists identify five ages of the human brain over a lifetime
Scientists warn mountain climate change is accelerating faster than predicted, putting billions of people at risk
The ocean is undergoing unprecedented, deep-reaching compound change
Autistic adults have an increased risk of suicidal behaviours, irrespective of trauma
Hospital bug jumps from lungs to gut, raising sepsis risk
Novel discovery reveals how brain protein OTULIN controls tau expression and could transform Alzheimer's treatment
How social risk and “happiness inequality” shape well-being across nations
Uncovering hidden losses in solar cells: A new analysis method reveals the nature of defects
Unveiling an anomalous electronic state opens a pathway to room-temperature superconductivity
Urban natives: Plants evolve to live in cities
Folklore sheds light on ancient Indian savannas
AI quake tools forecast aftershock risk in seconds, study shows
Prevalence of dysfunctional breathing in the Japanese community and the involvement of tobacco use status: The JASTIS study 2024
Genetic study links impulsive decision making to a wide range of health and psychiatric risks
Clinical trial using focused ultrasound with chemotherapy finds potential survival benefit for brain cancer patients
World-first platform for transparent, fair and equitable use of AI in healthcare
New guideline standardizes outpatient care for adults recovering from traumatic brain injury
[Press-News.org] Primary care physicians vital to complete care of prostate cancer patientsMen receiving androgen deprivation therapy need to be aware of effects it can have on their bones