PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Should you stop blood thinners before surgery? AAN guideline provides direction

2013-05-28
(Press-News.org) MINNEAPOLIS – A new guideline from the American Academy of Neurology will help people who take blood thinners decide whether or not to take them during surgery or other medical procedures. The guideline is published in the May 28, 2013, print issue of Neurology®, the medical journal of the American Academy of Neurology.

People who have had a stroke often take blood thinners such as aspirin or warfarin to prevent another stroke. Blood thinners, or anticlotting drugs, are also used to prevent a first stroke in people with atrial fibrillation, an irregular or fast heartbeat. Blood thinners can prevent blood clots from forming that can cause strokes. However, these drugs also can increase the risk of bleeding. Increased bleeding is especially a concern when someone is having a procedure or operation.

"There may be millions of Americans taking anticlotting drugs to prevent a stroke," said guideline author Melissa J. Armstrong, MD, an assistant professor of neurology with the University of Maryland School of Medicine in Baltimore. "For every dental procedure, minor medical procedure or surgery these people plan to have, they should work with their doctors to decide if these drugs should be continued to maintain stroke prevention efforts or temporarily stopped to lower the risk of bleeding with the procedure."

The risk of bleeding varies depending on the procedure, according to the guideline, which was developed by reviewing all available evidence to date. For many minor procedures, including dental procedures, the bleeding risk from continuing blood thinners is fairly small.

For some other procedures, the risk of bleeding may be higher when blood thinners are continued. Examples are certain hip and colon procedures.

"This guideline helps patients and doctors know what the evidence tells us about these different risks," Armstrong said. "A person's health history and preferred course of action are also important to discuss when making this decision."

Most of the studies on bleeding risks from blood thinners during procedures focus on aspirin and warfarin. Armstrong said more studies are needed to understand the bleeding risks of other blood thinners, such as clopidogrel and aspirin plus dipyridamole, as well as new anticoagulants such as dabigatran, rivaroxaban or apixaban, during or before procedures.

Some people take blood thinners for heart problems. The guideline did not review evidence for people with heart problems other than atrial fibrillation.

May is National Stroke Awareness Month.

### To learn more about stroke, visit http://www.aan.com/patients.

The American Academy of Neurology, an association of more than 26,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer's disease, stroke, migraine, multiple sclerosis, brain injury, Parkinson's disease and epilepsy. For more information about the American Academy of Neurology, visit http://www.aan.com or find us on Facebook, Twitter, Google+ and YouTube. Media Contacts: Rachel Seroka Michelle Uher, muher@aan.com, 612-928-6120


ELSE PRESS RELEASES FROM THIS DATE:

Stem cell injections improve spinal injuries in rats

2013-05-28
An international team led by researchers at the University of California, San Diego School of Medicine reports that a single injection of human neural stem cells produced neuronal regeneration and improvement of function and mobility in rats impaired by an acute spinal cord injury (SCI). The findings are published in the May 28, 2013 online issue of Stem Cell Research & Therapy. Martin Marsala, MD, professor in the Department of Anesthesiology, with colleagues at UC San Diego and in Slovakia, the Czech Republic and The Netherlands, said grafting neural stem cells derived ...

Down syndrome neurons grown from stem cells show signature problems

2013-05-28
Madison, Wis. – Down syndrome, the most common genetic form of intellectual disability, results from an extra copy of one chromosome. Although people with Down syndrome experience intellectual difficulties and other problems, scientists have had trouble identifying why that extra chromosome causes such widespread effects. In new research published this week, Anita Bhattacharyya, a neuroscientist at the Waisman Center at the University of Wisconsin-Madison, reports on brain cells that were grown from skin cells of individuals with Down syndrome. "Even though Down ...

Communication between physicians and patients important for expectations

2013-05-28
Seriously ill patients undergoing hemodialysis are more optimistic about their prognosis and prospects for transplants than their nephrologists, according to a study published online by JAMA Internal Medicine. The study also found that nephrologists rarely had discussed estimates of life-expectancy with their patients. Melissa W. Wachterman, M.D., M.P.H., from Veterans Affairs Boston Health Care System and colleagues compared patients' and physicians' expectations about one- and five-year survival rates and transplant candidacy among 207 patients undergoing hemodialysis ...

Patient participation in decision making associated with increased costs, services

2013-05-28
A survey of almost 22,000 admitted patients at the University of Chicago Medical Center found patient preference to participate in decision making concerning their care was associated with a longer length of stay and higher total hospitalization costs, according to a report published online by JAMA Internal Medicine. Hyo Jung Tak, Ph.D., and colleagues examined the relationship between patient preferences for participation in medical decision making and health care utilization among patients hospitalized between July 1, 2003 and August 31, 2011 by asking patients to ...

How patient centered are medical decisions?

2013-05-28
A national survey sample of adults who had discussions with their physicians in the preceding two years about common medical tests, medications and procedures often did not reflect a high level of shared decision making, according to an article published online by JAMA Internal Medicine. Floyd J. Fowler, Jr., Ph.D., from the Informed Medical Decisions Foundation and the University of Massachusetts, Boston, conducted a 2011 survey of a cross section of U.S. adults 40 years or older and asked them to indicate whether they reported making one of 10 medical decisions and ...

Decision making preferences among patients with heart attacks

2013-05-28
In a research letter, Harlan M. Krumholz, M.D., S.M., from Yale University School of Medicine and colleagues, "sought to investigate preferences for participation in the decision-making process among individuals hospitalized with an acute myocardial infarction ([AMI] or heart attack)." The researchers combined data from two similar AMI registries (TRIUMPH and PREMIER) which resulted in 6,636 patients in the study sample who were asked about who should make decisions on treatment options. "More than two-thirds of patients with AMI indicated a preference to play an active ...

Increase in unintentional marijuana ingestion among children following new drug laws in Colorado

2013-05-28
Following modification of drug enforcement laws for possession of marijuana in Colorado, there was an apparent increase in unintentional marijuana ingestions by young children, according to a report and accompanying editorials published Online First by JAMA Pediatrics, a JAMA Network publication. Several states and Washington, D.C. have enacted laws to decriminalize medical marijuana and two states, Colorado and Washington, have passed amendments to legalize the recreational use of marijuana. In late 2009, the Justice Department issued a policy instructing federal prosecutors ...

Salmonella uses protective switch during infection

2013-05-28
RICHLAND, Wash. -- For the first time, researchers have found a particular kind of molecular switch in the food poisoning bacteria Salmonella Typhimurium under infection-like conditions. This switch, using a process called S-thiolation, appears to be used by the bacteria to respond to changes in the environment during infection and might protect it from harm, researchers report this week online in the Proceedings of the National Academy of Sciences Early Edition. S-thiolation protects proteins from irreversible chemical changes when a cell is stressed. The newly discovered ...

Study examines placement of tobacco and alcohol brands in movies rated for youth audiences

2013-05-28
An analysis of top box-office movies released in the United States indicated tobacco brand producer placements in movies have declined since implementation of the Master Settlement Agreement (MSA), but alcohol placements, which are subject only to industry self-regulation, have increased in movies rated acceptable for youth audiences, according to a study published Online First by JAMA Pediatrics, a JAMA Network publication. There is growing evidence that movies influence substance use behaviors during adolescence. Children's exposure to movie imagery of tobacco and alcohol ...

Snail shell coiling programmed by protein patterning

2013-05-28
Snail shells coil in response to an lopsided protein gradient across their shell mantles, finds research in BioMed Central's open access journal EvoDevo. In contrast the shell mantle of limpets, whose shells do not coil, have a symmetrical pattern of the protein Decapentaplegic (Dpp). There are many hundreds of different kinds of gastropods (slugs snail and limpets) - second only in number of species to insects. They have adapted to live on land as well as in fresh water and marine environments, and have altered their physiology to survive in different habitats and to ...

LAST 30 PRESS RELEASES:

Intra-arterial tenecteplase for acute stroke after successful endovascular therapy

Study reveals beneficial microbes that can sustain yields in unfertilized fields

Robotic probe quickly measures key properties of new materials

Climate change cuts milk production, even when farmers cool their cows

Frozen, but not sealed: Arctic Ocean remained open to life during ice ages

Some like it cold: Cryorhodopsins

Demystifying gut bacteria with AI

Human wellbeing on a finite planet towards 2100: new study shows humanity at a crossroads

Unlocking the hidden biodiversity of Europe’s villages

Planned hydrogen refuelling stations may lead to millions of euros in yearly losses

Planned C-sections increase the risk of certain childhood cancers

Adults who have survived childhood cancer are at increased risk of severe COVID-19

Drones reveal extreme coral mortality after bleaching

New genetic finding uncovers hidden cause of arsenic resistance in acute promyelocytic leukemia

Native habitats hold the key to the much-loved smashed avocado’s future

Using lightning to make ammonia out of thin air

Machine learning potential-driven insights into pH-dependent CO₂ reduction

Physician associates provide safe care for diagnosed patients when directly supervised by a doctor

How game-play with robots can bring out their human side

Asthma: patient expectations influence the course of the disease

UNM physician tests drug that causes nerve tissue to emit light, enabling faster, safer surgery

New study identifies EMP1 as a key driver of pancreatic cancer progression and poor prognosis

XPR1 identified as a key regulator of ovarian cancer growth through autophagy and immune evasion

Flexible, eco-friendly electronic plastic for wearable tech, sensors

Can the Large Hadron Collider snap string theory?

Stuckeman professor’s new book explores ‘socially sustainable’ architecture

Synthetic DNA nanoparticles for gene therapy

New model to find treatments for an aggressive blood cancer

Special issue of Journal of Intensive Medicine analyzes non-invasive respiratory support

T cells take aim at Chikungunya virus

[Press-News.org] Should you stop blood thinners before surgery? AAN guideline provides direction